| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | prednisolone 9.9 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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77 genes differentially expressed following the CRCGN011_HEPG2_24H:F21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPARG | peroxisome proliferator-activated receptor gamma | 5.38185 |
| UBQLN2 | ubiquilin 2 | 5.0584 |
| E2F2 | E2F transcription factor 2 | 4.7888 |
| ADRB2 | adrenoceptor beta 2, surface | 4.7605 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 4.47832 |
| MAMLD1 | mastermind-like domain containing 1 | 4.196 |
| STIMATE | STIM activating enhancer | 4.06575 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.9676 |
| LSR | lipolysis stimulated lipoprotein receptor | 3.87015 |
| MAP7 | microtubule-associated protein 7 | 3.85625 |
| ATP11B | ATPase, class VI, type 11B | 3.54425 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 3.28209 |
| IDE | insulin-degrading enzyme | 3.25572 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase | 3.01215 |
| GATA3 | GATA binding protein 3 | 2.92387 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 2.886 |
| GCH1 | GTP cyclohydrolase 1 | 2.87745 |
| DDIT4 | DNA-damage-inducible transcript 4 | 2.85 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.76722 |
| EXOSC4 | exosome component 4 | 2.68217 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.59115 |
| RNF167 | ring finger protein 167 | 2.58065 |
| KCNA3 | potassium channel, voltage gated shaker related subfamily A, member 3 | 2.5332 |
| LCN2 | lipocalin 2 | 2.48215 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.4615 |
| MTERF3 | mitochondrial transcription termination factor 3 | 2.43195 |
| CCNA1 | cyclin A1 | 2.4037 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) | 2.2696 |
| PEF1 | penta-EF-hand domain containing 1 | 2.22785 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | 2.16075 |
| TENT5C | terminal nucleotidyltransferase 5C | 2.15675 |
| CITED1 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 | 2.0988 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 2.0809 |
| CYCS | cytochrome c, somatic | 2.0525 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.05102 |
| STS | steroid sulfatase (microsomal), isozyme S | 2.04475 |
| GATA2 | GATA binding protein 2 | 2.02215 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIB3 | tribbles pseudokinase 3 | -10.0 |
| CCNB2 | cyclin B2 | -8.5573 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | -5.6671 |
| ADI1 | acireductone dioxygenase 1 | -5.28625 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -5.1043 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -5.0 |
| GDF15 | growth differentiation factor 15 | -5.0 |
| LDHD | lactate dehydrogenase D | -4.9573 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -4.71305 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -4.6686 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.64695 |
| MRPS2 | mitochondrial ribosomal protein S2 | -4.5935 |
| NGRN | neugrin, neurite outgrowth associated | -4.20895 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa | -3.56485 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.53915 |
| IPO13 | importin 13 | -3.47945 |
| TBCB | tubulin folding cofactor B | -3.3832 |
| GNAS | GNAS complex locus | -3.30569 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.12757 |
| PIK3R4 | phosphoinositide-3-kinase, regulatory subunit 4 | -2.95895 |
| SLC35F2 | solute carrier family 35, member F2 | -2.9141 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.83318 |
| COX6B1 | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) | -2.70445 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.64245 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.59725 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -2.4159 |
| CAPNS1 | calpain, small subunit 1 | -2.35745 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.298 |
| SELENOW | selenoprotein W | -2.276 |
| PENK | proenkephalin | -2.25775 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | -2.24075 |
| PFDN1 | prefoldin subunit 1 | -2.2208 |
| RBMX | RNA binding motif protein, X-linked | -2.2035 |
| ZNF32 | zinc finger protein 32 | -2.1584 |
| NDUFS4 | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | -2.14995 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 | -2.1312 |
| NMRK2 | nicotinamide riboside kinase 2 | -2.0966 |
| TRIM39-RPP21 | TRIM39-RPP21 readthrough | -2.02555 |
| POMZP3 | POM121 and ZP3 fusion | -2.02198 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | -2.00195 |
