CRCGN011_HEPG2_24H:G03 Gene Set
Genes
54 genes differentially expressed following the CRCGN011_HEPG2_24H:G03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
5.17285
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.08185
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
4.82337
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.80165
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.70795
|
|
MAP7
|
microtubule-associated protein 7
|
4.5868
|
|
UBQLN2
|
ubiquilin 2
|
4.44755
|
|
LAGE3
|
L antigen family, member 3
|
4.36875
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
4.24085
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
4.03897
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.02855
|
|
PRKCH
|
protein kinase C, eta
|
3.4828
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
3.2347
|
|
PLXNB2
|
plexin B2
|
2.79395
|
|
COL11A1
|
collagen, type XI, alpha 1
|
2.77558
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.41593
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
2.3079
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
2.28625
|
|
FASTKD5
|
FAST kinase domains 5
|
2.28105
|
|
CCNF
|
cyclin F
|
2.21162
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.1826
|
|
DNM1
|
dynamin 1
|
2.16625
|
|
ARAP2
|
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
|
2.1575
|
|
HDAC2
|
histone deacetylase 2
|
2.10385
|
|
CHN1
|
chimerin 1
|
2.10325
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
VAT1
|
vesicle amine transport 1
|
-10.0
|
|
GNAS
|
GNAS complex locus
|
-7.39948
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-5.09605
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-5.0253
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-4.8266
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.4392
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.4276
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-4.00012
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.94385
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.75495
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.66925
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.65788
|
|
RAI14
|
retinoic acid induced 14
|
-3.53015
|
|
CCNB2
|
cyclin B2
|
-3.5046
|
|
RGS2
|
regulator of G-protein signaling 2
|
-3.40625
|
|
YME1L1
|
YME1-like 1 ATPase
|
-3.15982
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-2.91247
|
|
CD320
|
CD320 molecule
|
-2.8526
|
|
COG7
|
component of oligomeric golgi complex 7
|
-2.5795
|
|
FAM110B
|
family with sequence similarity 110, member B
|
-2.4131
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.2914
|
|
REEP2
|
receptor accessory protein 2
|
-2.2119
|
|
AHCY
|
adenosylhomocysteinase
|
-2.1824
|
|
CDC42
|
cell division cycle 42
|
-2.11069
|
|
TPSG1
|
tryptase gamma 1
|
-2.0888
|
|
TRMT2B
|
tRNA methyltransferase 2 homolog B (S. cerevisiae)
|
-2.0863
|
|
BTBD2
|
BTB (POZ) domain containing 2
|
-2.05705
|
|
DAD1
|
defender against cell death 1
|
-2.00495
|
|
COLGALT2
|
collagen beta(1-O)galactosyltransferase 2
|
-2.0008
|
