| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | triphenyl phosphate 4.97 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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49 genes differentially expressed following the CRCGN011_HEPG2_24H:G04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYCS | cytochrome c, somatic | 5.8146 |
| NMU | neuromedin U | 5.5752 |
| MAMLD1 | mastermind-like domain containing 1 | 5.1347 |
| KLHL9 | kelch-like family member 9 | 5.0938 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.09235 |
| CSK | c-src tyrosine kinase | 5.0 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.9223 |
| STK10 | serine/threonine kinase 10 | 4.86933 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.8362 |
| SOCS2 | suppressor of cytokine signaling 2 | 4.1746 |
| EPN2 | epsin 2 | 3.5375 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 3.26225 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 3.19394 |
| NOSIP | nitric oxide synthase interacting protein | 3.08105 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 2.97325 |
| RNF167 | ring finger protein 167 | 2.8409 |
| MCM3 | minichromosome maintenance complex component 3 | 2.70255 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 2.5768 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.57337 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 2.4982 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.4452 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 | 2.4267 |
| PMM2 | phosphomannomutase 2 | 2.2916 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.2908 |
| GPATCH8 | G patch domain containing 8 | 2.2018 |
| CEP57 | centrosomal protein 57kDa | 2.16678 |
| CDC7 | cell division cycle 7 | 2.06445 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KDM3A | lysine (K)-specific demethylase 3A | -4.83785 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.7725 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.50095 |
| ADI1 | acireductone dioxygenase 1 | -4.22665 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.51865 |
| GNAS | GNAS complex locus | -3.28828 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -3.08915 |
| PCNA | proliferating cell nuclear antigen | -3.01975 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -2.94944 |
| RBM34 | RNA binding motif protein 34 | -2.71933 |
| CCNB2 | cyclin B2 | -2.64875 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.55527 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -2.36249 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.3613 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.35901 |
| SEC14L5 | SEC14-like 5 (S. cerevisiae) | -2.26265 |
| SNTB2 | syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) | -2.245 |
| LGALS14 | lectin, galactoside-binding, soluble, 14 | -2.1481 |
| GLRA2 | glycine receptor, alpha 2 | -2.1424 |
| GPR173 | G protein-coupled receptor 173 | -2.1272 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -2.11765 |
| AMBN | ameloblastin (enamel matrix protein) | -2.08225 |