CRCGN011_HEPG2_24H:G04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description triphenyl phosphate 4.97 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

49 genes differentially expressed following the CRCGN011_HEPG2_24H:G04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CYCS cytochrome c, somatic 5.8146
NMU neuromedin U 5.5752
MAMLD1 mastermind-like domain containing 1 5.1347
KLHL9 kelch-like family member 9 5.0938
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 5.09235
CSK c-src tyrosine kinase 5.0
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.9223
STK10 serine/threonine kinase 10 4.86933
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 4.8362
SOCS2 suppressor of cytokine signaling 2 4.1746
EPN2 epsin 2 3.5375
DYNLT3 dynein, light chain, Tctex-type 3 3.26225
CASP2 caspase 2, apoptosis-related cysteine peptidase 3.19394
NOSIP nitric oxide synthase interacting protein 3.08105
ADGRE5 adhesion G protein-coupled receptor E5 2.97325
RNF167 ring finger protein 167 2.8409
MCM3 minichromosome maintenance complex component 3 2.70255
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 2.5768
TIAM1 T-cell lymphoma invasion and metastasis 1 2.57337
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 2.4982
GPER1 G protein-coupled estrogen receptor 1 2.4452
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 2.4267
PMM2 phosphomannomutase 2 2.2916
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.2908
GPATCH8 G patch domain containing 8 2.2018
CEP57 centrosomal protein 57kDa 2.16678
CDC7 cell division cycle 7 2.06445

decreased expression

Symbol Name Standardized Value
KDM3A lysine (K)-specific demethylase 3A -4.83785
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.7725
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -4.50095
ADI1 acireductone dioxygenase 1 -4.22665
OXA1L oxidase (cytochrome c) assembly 1-like -3.51865
GNAS GNAS complex locus -3.28828
NR2F6 nuclear receptor subfamily 2, group F, member 6 -3.08915
PCNA proliferating cell nuclear antigen -3.01975
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -2.94944
RBM34 RNA binding motif protein 34 -2.71933
CCNB2 cyclin B2 -2.64875
ITGB1BP1 integrin beta 1 binding protein 1 -2.55527
SNCA synuclein, alpha (non A4 component of amyloid precursor) -2.36249
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -2.3613
EIF5 eukaryotic translation initiation factor 5 -2.35901
SEC14L5 SEC14-like 5 (S. cerevisiae) -2.26265
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) -2.245
LGALS14 lectin, galactoside-binding, soluble, 14 -2.1481
GLRA2 glycine receptor, alpha 2 -2.1424
GPR173 G protein-coupled receptor 173 -2.1272
FGD6 FYVE, RhoGEF and PH domain containing 6 -2.11765
AMBN ameloblastin (enamel matrix protein) -2.08225