| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | triphenyl phosphate 2.49 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
91 genes differentially expressed following the CRCGN011_HEPG2_24H:G05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYLK | myosin light chain kinase | 10.0 |
| CCL2 | chemokine (C-C motif) ligand 2 | 8.0626 |
| MAMLD1 | mastermind-like domain containing 1 | 5.6625 |
| KLHL21 | kelch-like family member 21 | 5.64605 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 5.5852 |
| AMDHD2 | amidohydrolase domain containing 2 | 5.2898 |
| CSK | c-src tyrosine kinase | 5.1477 |
| MSRA | methionine sulfoxide reductase A | 4.9045 |
| NFIL3 | nuclear factor, interleukin 3 regulated | 4.25025 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 4.19895 |
| MAP7 | microtubule-associated protein 7 | 3.90977 |
| MEST | mesoderm specific transcript | 3.907 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 3.61765 |
| CYCS | cytochrome c, somatic | 3.5682 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 3.43265 |
| COQ8A | coenzyme Q8A | 3.427 |
| PMM2 | phosphomannomutase 2 | 3.41985 |
| FZD1 | frizzled class receptor 1 | 3.3993 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 3.2827 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 3.26475 |
| KDM5A | lysine (K)-specific demethylase 5A | 3.22078 |
| UBE2A | ubiquitin-conjugating enzyme E2A | 3.20725 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.04745 |
| EDN1 | endothelin 1 | 2.98985 |
| VGLL4 | vestigial-like family member 4 | 2.84658 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.7957 |
| ZNF589 | zinc finger protein 589 | 2.77207 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 2.6342 |
| CSPG4 | chondroitin sulfate proteoglycan 4 | 2.63325 |
| PRR15L | proline rich 15-like | 2.632 |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 | 2.5543 |
| MMP2 | matrix metallopeptidase 2 | 2.4673 |
| RRP8 | ribosomal RNA processing 8, methyltransferase, homolog (yeast) | 2.45625 |
| MSL1 | male-specific lethal 1 homolog (Drosophila) | 2.27125 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.25948 |
| FADD | Fas (TNFRSF6)-associated via death domain | 2.2333 |
| PDZRN3 | PDZ domain containing ring finger 3 | 2.2208 |
| NAT10 | N-acetyltransferase 10 (GCN5-related) | 2.19965 |
| KCTD5 | potassium channel tetramerization domain containing 5 | 2.18385 |
| LAD1 | ladinin 1 | 2.15965 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa | 2.14875 |
| TPD52L2 | tumor protein D52-like 2 | 2.09905 |
| ARHGEF9 | Cdc42 guanine nucleotide exchange factor (GEF) 9 | 2.06335 |
| EEF1E1 | eukaryotic translation elongation factor 1 epsilon 1 | 2.0513 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | 2.03 |
| MORC4 | MORC family CW-type zinc finger 4 | 2.02765 |
| EED | embryonic ectoderm development | 2.0266 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal | 2.0067 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -8.33885 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -4.9233 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.7308 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -4.32075 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -4.16815 |
| CCNB2 | cyclin B2 | -4.11765 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -3.89325 |
| LAP3 | leucine aminopeptidase 3 | -3.8348 |
| YME1L1 | YME1-like 1 ATPase | -3.81363 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.5785 |
| SLC35F2 | solute carrier family 35, member F2 | -3.50235 |
| GNAS | GNAS complex locus | -3.45968 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -3.34832 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -3.22575 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -2.8206 |
| ADI1 | acireductone dioxygenase 1 | -2.7609 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -2.7374 |
| SNX11 | sorting nexin 11 | -2.73715 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.72722 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.7128 |
| IFT46 | intraflagellar transport 46 | -2.5221 |
| TRMT5 | tRNA methyltransferase 5 | -2.49485 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -2.4692 |
| STAMBP | STAM binding protein | -2.44875 |
| NCK2 | NCK adaptor protein 2 | -2.4487 |
| GET1 | guided entry of tail-anchored proteins factor 1 | -2.4172 |
| UBAC1 | UBA domain containing 1 | -2.3761 |
| PRPF4 | pre-mRNA processing factor 4 | -2.29953 |
| LINC02762 | long intergenic non-protein coding RNA 2762 | -2.27495 |
| CRLF1 | cytokine receptor-like factor 1 | -2.273 |
| SIX2 | SIX homeobox 2 | -2.25435 |
| KDM1A | lysine (K)-specific demethylase 1A | -2.17745 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -2.171 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 | -2.1192 |
| ZW10 | zw10 kinetochore protein | -2.11625 |
| CD82 | CD82 molecule | -2.0867 |
| CEP85 | centrosomal protein 85kDa | -2.07255 |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit | -2.06595 |
| ATXN2 | ataxin 2 | -2.0401 |
| LY86 | lymphocyte antigen 86 | -2.02725 |
| IFI44L | interferon-induced protein 44-like | -2.02135 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 | -2.01975 |
| TBXT | T-box transcription factor T | -2.0149 |
