| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | triphenyl phosphate 1.24 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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73 genes differentially expressed following the CRCGN011_HEPG2_24H:G06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UBQLN2 | ubiquilin 2 | 5.4638 |
| DENND2D | DENN/MADD domain containing 2D | 5.3965 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 5.24715 |
| CHMP6 | charged multivesicular body protein 6 | 5.2424 |
| CSK | c-src tyrosine kinase | 4.91515 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 4.90345 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | 4.5333 |
| STIMATE | STIM activating enhancer | 4.3109 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.20255 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.1893 |
| BIRC2 | baculoviral IAP repeat containing 2 | 3.91965 |
| PFKL | phosphofructokinase, liver | 3.7179 |
| MAP7 | microtubule-associated protein 7 | 3.6867 |
| VGLL4 | vestigial-like family member 4 | 3.38825 |
| SOCS2 | suppressor of cytokine signaling 2 | 3.32647 |
| KLHL9 | kelch-like family member 9 | 3.16195 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 3.08895 |
| COQ8A | coenzyme Q8A | 3.00115 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | 2.9795 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.9245 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.864 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.66135 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.62173 |
| MMP2 | matrix metallopeptidase 2 | 2.5291 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 2.48605 |
| NMU | neuromedin U | 2.41335 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 2.3686 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | 2.2691 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 2.2098 |
| SFTPD | surfactant protein D | 2.18005 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 2.15775 |
| PODXL2 | podocalyxin-like 2 | 2.13435 |
| TRMT61B | tRNA methyltransferase 61B | 2.0995 |
| INF2 | inverted formin, FH2 and WH2 domain containing | 2.09135 |
| HPCAL1 | hippocalcin-like 1 | 2.085 |
| RANGAP1 | Ran GTPase activating protein 1 | 2.07037 |
| GATD3 | glutamine amidotransferase class 1 domain containing 3 | 2.05872 |
| RASIP1 | Ras interacting protein 1 | 2.0312 |
| METRN | meteorin, glial cell differentiation regulator | 2.02815 |
| TGM3 | transglutaminase 3 | 2.01035 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SCAND1 | SCAN domain containing 1 | -5.67705 |
| UGDH | UDP-glucose 6-dehydrogenase | -5.48955 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -5.39595 |
| LDHD | lactate dehydrogenase D | -5.24985 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -5.08935 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.0 |
| COG2 | component of oligomeric golgi complex 2 | -4.92225 |
| PCNA | proliferating cell nuclear antigen | -4.7455 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.62155 |
| BLCAP | bladder cancer associated protein | -4.4846 |
| LYPLA1 | lysophospholipase I | -3.8563 |
| CD58 | CD58 molecule | -3.70832 |
| GDF15 | growth differentiation factor 15 | -3.69165 |
| GNAS | GNAS complex locus | -3.66016 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.3577 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -3.25685 |
| WASHC4 | WASH complex subunit 4 | -3.07007 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -3.00153 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -2.69865 |
| S100PBP | S100P binding protein | -2.53425 |
| AGBL2 | ATP/GTP binding protein-like 2 | -2.5079 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.49035 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -2.3982 |
| NGRN | neugrin, neurite outgrowth associated | -2.3743 |
| RAI14 | retinoic acid induced 14 | -2.3585 |
| PRPF4 | pre-mRNA processing factor 4 | -2.26853 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | -2.22085 |
| UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) | -2.14475 |
| RGS2 | regulator of G-protein signaling 2 | -2.08845 |
| FOXO4 | forkhead box O4 | -2.06305 |
| MINAR1 | membrane integral NOTCH2 associated receptor 1 | -2.05795 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -2.0307 |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 | -2.00305 |