| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | fd & c blue no. 2 40.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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83 genes differentially expressed following the CRCGN011_HEPG2_24H:G07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 7.83705 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 5.7513 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 5.1715 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 4.95375 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.70055 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 4.6263 |
| UBQLN2 | ubiquilin 2 | 4.5099 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 4.23425 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 4.02032 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 3.81417 |
| RXYLT1 | ribitol xylosyltransferase 1 | 3.51653 |
| CYCS | cytochrome c, somatic | 3.44875 |
| RAB11FIP2 | RAB11 family interacting protein 2 (class I) | 3.2651 |
| KLHL9 | kelch-like family member 9 | 3.1254 |
| KDM5A | lysine (K)-specific demethylase 5A | 3.11 |
| TEX10 | testis expressed 10 | 2.8984 |
| ACTL7A | actin-like 7A | 2.67685 |
| DIPK1A | divergent protein kinase domain 1A | 2.63925 |
| ACVR2B | activin A receptor, type IIB | 2.5223 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.51527 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 2.45843 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.4432 |
| GPATCH8 | G patch domain containing 8 | 2.324 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 | 2.295 |
| EPHB2 | EPH receptor B2 | 2.24365 |
| LAX1 | lymphocyte transmembrane adaptor 1 | 2.2254 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.16565 |
| TDRD7 | tudor domain containing 7 | 2.1601 |
| STBD1 | starch binding domain 1 | 2.1415 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 2.10072 |
| CDCA4 | cell division cycle associated 4 | 2.08835 |
| BIRC2 | baculoviral IAP repeat containing 2 | 2.08565 |
| DHX58 | DEXH (Asp-Glu-X-His) box polypeptide 58 | 2.079 |
| LCN2 | lipocalin 2 | 2.0761 |
| MPC2 | mitochondrial pyruvate carrier 2 | 2.0718 |
| GATA2 | GATA binding protein 2 | 2.06645 |
| SLC35A5 | solute carrier family 35, member A5 | 2.06425 |
| IFI6 | interferon, alpha-inducible protein 6 | 2.05015 |
| KIF17 | kinesin family member 17 | 2.04375 |
| PRDX4 | peroxiredoxin 4 | 2.02535 |
| TMEM74B | transmembrane protein 74B | 2.02375 |
| EXT2 | exostosin glycosyltransferase 2 | 2.02352 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 2.01505 |
| CHN1 | chimerin 1 | 2.00455 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -8.8605 |
| AARS1 | alanyl-tRNA synthetase 1 | -5.1548 |
| GDF15 | growth differentiation factor 15 | -5.1192 |
| CCDC86 | coiled-coil domain containing 86 | -4.9 |
| CDC20 | cell division cycle 20 | -4.66275 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -4.6149 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -4.5745 |
| PEG10 | paternally expressed 10 | -4.40105 |
| MAP7 | microtubule-associated protein 7 | -3.94125 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.82655 |
| YME1L1 | YME1-like 1 ATPase | -3.70738 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.49895 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.4278 |
| GNAS | GNAS complex locus | -3.41754 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -3.3745 |
| CCNB2 | cyclin B2 | -2.9204 |
| TLCD3A | TLC domain containing 3A | -2.9053 |
| HEATR1 | HEAT repeat containing 1 | -2.73612 |
| DSG2 | desmoglein 2 | -2.70425 |
| RNF167 | ring finger protein 167 | -2.5875 |
| TCERG1 | transcription elongation regulator 1 | -2.5714 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.48495 |
| WDR7 | WD repeat domain 7 | -2.42335 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.41597 |
| ZNF586 | zinc finger protein 586 | -2.3804 |
| PRPF4 | pre-mRNA processing factor 4 | -2.36247 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -2.29895 |
| HOXB5 | homeobox B5 | -2.28053 |
| MOCS2 | molybdenum cofactor synthesis 2 | -2.2212 |
| TYK2 | tyrosine kinase 2 | -2.2013 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -2.1899 |
| TWF2 | twinfilin actin binding protein 2 | -2.18525 |
| RAD51C | RAD51 paralog C | -2.18425 |
| HMG20B | high mobility group 20B | -2.10745 |
| KLK1 | kallikrein 1 | -2.07975 |
| RBM34 | RNA binding motif protein 34 | -2.03583 |
| NAV2 | neuron navigator 2 | -2.0017 |
| IFT140 | intraflagellar transport 140 | -2.0014 |
