CRCGN011_HEPG2_24H:G16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description withaferin-a 2.5 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

486 genes differentially expressed following the CRCGN011_HEPG2_24H:G16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABHD4 abhydrolase domain containing 4 10.0
PPARG peroxisome proliferator-activated receptor gamma 10.0
LCN2 lipocalin 2 9.49885
HMOX1 heme oxygenase 1 9.3687
HSPA1A heat shock 70kDa protein 1A 8.4491
TXNRD1 thioredoxin reductase 1 7.36645
MCOLN1 mucolipin 1 7.30725
KLHL21 kelch-like family member 21 6.7863
FOSL1 FOS-like antigen 1 6.07445
TIMP2 TIMP metallopeptidase inhibitor 2 5.91935
SQOR sulfide quinone oxidoreductase 5.83245
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 5.649
CIAO3 cytosolic iron-sulfur assembly component 3 5.6081
TATDN2 TatD DNase domain containing 2 5.5135
GPATCH8 G patch domain containing 8 5.38928
MVP major vault protein 5.35745
SQSTM1 sequestosome 1 5.34418
NOTCH1 notch 1 5.15575
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 4.88095
CCL2 chemokine (C-C motif) ligand 2 4.8729
ADRB2 adrenoceptor beta 2, surface 4.66275
EPHA3 EPH receptor A3 4.53753
CBR1 carbonyl reductase 1 4.31845
ALAS1 5'-aminolevulinate synthase 1 4.23785
TRAM2 translocation associated membrane protein 2 4.19163
H2BC12 H2B clustered histone 12 4.17957
MUC13 mucin 13, cell surface associated 4.14935
PPP1R13B protein phosphatase 1, regulatory subunit 13B 4.04715
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3.96805
KLHL9 kelch-like family member 9 3.92773
MYLK myosin light chain kinase 3.798
KEAP1 kelch-like ECH-associated protein 1 3.7943
DYNLT3 dynein, light chain, Tctex-type 3 3.7083
VAT1 vesicle amine transport 1 3.61615
ABHD6 abhydrolase domain containing 6 3.57158
TEX10 testis expressed 10 3.56845
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 3.5592
UGDH UDP-glucose 6-dehydrogenase 3.555
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 3.52055
BAX BCL2-associated X protein 3.51343
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 3.444
LRP10 low density lipoprotein receptor-related protein 10 3.37435
RBKS ribokinase 3.3728
KIF5C kinesin family member 5C 3.36977
MAP3K14 mitogen-activated protein kinase kinase kinase 14 3.33255
NQO1 NAD(P)H dehydrogenase, quinone 1 3.32147
ADGRE5 adhesion G protein-coupled receptor E5 3.2822
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 3.2687
PLS1 plastin 1 3.2259
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 3.1984
ARL14 ADP-ribosylation factor-like 14 3.1245
GPX2 glutathione peroxidase 2 3.1226
CNPY3 canopy FGF signaling regulator 3 3.09405
ANKRD12 ankyrin repeat domain 12 3.04395
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 3.0419
NPC1 Niemann-Pick disease, type C1 3.03653
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 3.03245
P3H2 prolyl 3-hydroxylase 2 3.0285
SKIC8 SKI8 subunit of superkiller complex 3.0267
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 3.0205
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 3.00685
EMC3 ER membrane protein complex subunit 3 2.9656
AKR1C3 aldo-keto reductase family 1, member C3 2.93105
AKR1C1 aldo-keto reductase family 1, member C1 2.92343
DNM2 dynamin 2 2.90245
MICALL1 MICAL-like 1 2.89885
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.8814
NKX2-5 NK2 homeobox 5 2.88115
AARS1 alanyl-tRNA synthetase 1 2.87925
TRIM16 tripartite motif containing 16 2.8656
ALG3 ALG3, alpha-1,3- mannosyltransferase 2.85765
DENND1B DENN/MADD domain containing 1B 2.8552
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 2.8344
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 2.831
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 2.8215
FZD7 frizzled class receptor 7 2.80285
SERTAD2 SERTA domain containing 2 2.80215
GSR glutathione reductase 2.79165
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1 2.79055
CARMIL1 capping protein regulator and myosin 1 linker 1 2.78585
IL2RB interleukin 2 receptor, beta 2.7821
LRRC41 leucine rich repeat containing 41 2.7745
SLC38A6 solute carrier family 38, member 6 2.75445
PFKL phosphofructokinase, liver 2.7461
PGRMC1 progesterone receptor membrane component 1 2.74013
KLRB1 killer cell lectin-like receptor subfamily B, member 1 2.73995
NME8 NME/NM23 family member 8 2.739
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 2.7356
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 2.7219
ZW10 zw10 kinetochore protein 2.68355
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) 2.67415
EPS8L3 EPS8-like 3 2.6739
TPRA1 transmembrane protein, adipocyte asscociated 1 2.6728
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 2.672
TMEM50A transmembrane protein 50A 2.66855
DUSP3 dual specificity phosphatase 3 2.65878
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 2.65395
KRT20 keratin 20, type I 2.6438
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 2.63685
CGRRF1 cell growth regulator with ring finger domain 1 2.6285
TERF2IP telomeric repeat binding factor 2, interacting protein 2.6237
PARL presenilin associated, rhomboid-like 2.6048
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.59482
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 2.58615
AP2M1 adaptor-related protein complex 2, mu 1 subunit 2.5778
WNT5B wingless-type MMTV integration site family, member 5B 2.54765
RASA4B RAS p21 protein activator 4B 2.52365
DNASE1L3 deoxyribonuclease I-like 3 2.52285
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 2.51996
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 2.5145
ADRM1 adhesion regulating molecule 1 2.51215
BIRC2 baculoviral IAP repeat containing 2 2.5024
LPO lactoperoxidase 2.50225
CHEK1 checkpoint kinase 1 2.50025
FOXO4 forkhead box O4 2.4985
JUN jun proto-oncogene 2.49735
H2BC21 H2B clustered histone 21 2.49525
IL7R interleukin 7 receptor 2.48625
TRPA1 transient receptor potential cation channel, subfamily A, member 1 2.47918
IL6 interleukin 6 2.4782
ITFG1 integrin alpha FG-GAP repeat containing 1 2.451
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 2.44375
IL18RAP interleukin 18 receptor accessory protein 2.43785
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 2.43115
TRIM31 tripartite motif containing 31 2.42658
YPEL5 yippee-like 5 (Drosophila) 2.425
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) 2.41635
FOXF2 forkhead box F2 2.41555
HOXD11 homeobox D11 2.41175
ADGRG3 adhesion G protein-coupled receptor G3 2.40825
MUTYH mutY homolog 2.4065
FASLG Fas ligand (TNF superfamily, member 6) 2.40385
TM9SF2 transmembrane 9 superfamily member 2 2.39345
CTLA4 cytotoxic T-lymphocyte-associated protein 4 2.38655
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) 2.3833
ZNF423 zinc finger protein 423 2.3813
BAG2 BCL2-associated athanogene 2 2.3744
RNASE7 ribonuclease, RNase A family, 7 2.37223
CCDC71 coiled-coil domain containing 71 2.3692
GCLC glutamate-cysteine ligase, catalytic subunit 2.36102
GARRE1 granule associated Rac and RHOG effector 1 2.35265
PTPN1 protein tyrosine phosphatase, non-receptor type 1 2.3381
FAM110B family with sequence similarity 110, member B 2.33685
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 2.3304
GADD45A growth arrest and DNA-damage-inducible, alpha 2.33025
ARL8B ADP-ribosylation factor-like 8B 2.32845
KCTD9 potassium channel tetramerization domain containing 9 2.31635
ITGA9 integrin, alpha 9 2.31285
CD2 CD2 molecule 2.3035
ELF4 E74-like factor 4 (ets domain transcription factor) 2.2975
ANKRD44 ankyrin repeat domain 44 2.2868
ANGPT1 angiopoietin 1 2.27885
RNF113A ring finger protein 113A 2.27465
GOLGA8A golgin A8 family, member A 2.274
PDE1A phosphodiesterase 1A, calmodulin-dependent 2.27395
CST5 cystatin D 2.27355
CCNJL cyclin J-like 2.27225
NAGK N-acetylglucosamine kinase 2.2679
GALNS galactosamine (N-acetyl)-6-sulfatase 2.26785
CHN1 chimerin 1 2.2676
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 2.26635
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 2.26465
PCDHB16 protocadherin beta 16 2.25542
SPINK1 serine peptidase inhibitor, Kazal type 1 2.2439
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 2.2403
LHFPL2 lipoma HMGIC fusion partner-like 2 2.23965
MPZL1 myelin protein zero-like 1 2.23379
MSX2 msh homeobox 2 2.23038
SNAI2 snail family zinc finger 2 2.2213
INPP1 inositol polyphosphate-1-phosphatase 2.22015
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 2.2165
PODNL1 podocan-like 1 2.21635
SOWAHC sosondowah ankyrin repeat domain family member C 2.2116
CLIC5 chloride intracellular channel 5 2.20887
VILL villin-like 2.20565
CBX6 chromobox homolog 6 2.20512
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 2.20455
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 2.19745
IQCB1 IQ motif containing B1 2.196
MUC3B mucin 3B, cell surface associated 2.18515
NID2 nidogen 2 (osteonidogen) 2.17515
HOXD10 homeobox D10 2.1736
UBR2 ubiquitin protein ligase E3 component n-recognin 2 2.17285
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 2.1727
ANGPTL2 angiopoietin-like 2 2.17023
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 2.16935
ARID3A AT rich interactive domain 3A (BRIGHT-like) 2.16785
RIPOR1 RHO family interacting cell polarization regulator 1 2.16668
EHBP1L1 EH domain binding protein 1-like 1 2.16388
LGALS4 lectin, galactoside-binding, soluble, 4 2.1596
RHD Rh blood group, D antigen 2.1582
SCPEP1 serine carboxypeptidase 1 2.15645
PIR pirin (iron-binding nuclear protein) 2.15195
WDR44 WD repeat domain 44 2.14935
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.1492
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) 2.14725
TM4SF20 transmembrane 4 L six family member 20 2.14505
HCCS holocytochrome c synthase 2.14418
USB1 U6 snRNA biogenesis 1 2.14395
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 2.14395
SIAH1 siah E3 ubiquitin protein ligase 1 2.1418
SYNPO synaptopodin 2.14175
FNDC3B fibronectin type III domain containing 3B 2.1396
ZMYM1 zinc finger, MYM-type 1 2.13445
MCHR1 melanin-concentrating hormone receptor 1 2.1295
MTERF3 mitochondrial transcription termination factor 3 2.12815
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 2.12805
ZNF609 zinc finger protein 609 2.12605
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 2.11965
NGF nerve growth factor (beta polypeptide) 2.1176
BBC3 BCL2 binding component 3 2.10905
ADTRP androgen-dependent TFPI-regulating protein 2.10595
NABP1 nucleic acid binding protein 1 2.103
EMILIN1 elastin microfibril interfacer 1 2.1007
ZNF222 zinc finger protein 222 2.0999
KDM5C lysine (K)-specific demethylase 5C 2.0983
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 2.09673
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 2.09645
TMEM127 transmembrane protein 127 2.09335
ASNS asparagine synthetase (glutamine-hydrolyzing) 2.0877
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.0871
DAPK2 death-associated protein kinase 2 2.08585
FECH ferrochelatase 2.08385
AGO2 argonaute RISC catalytic component 2 2.0812
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit 2.07927
NUAK2 NUAK family, SNF1-like kinase, 2 2.07855
LOC128125814 uncharacterized LOC128125814 2.07035
CD247 CD247 molecule 2.07
TIPIN TIMELESS interacting protein 2.06935
METTL4 methyltransferase like 4 2.0682
BDKRB1 bradykinin receptor B1 2.0643
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 2.06255
PCBP3 poly(rC) binding protein 3 2.06115
GNPDA1 glucosamine-6-phosphate deaminase 1 2.05735
GHITM growth hormone inducible transmembrane protein 2.0509
GABARAPL1 GABA(A) receptor-associated protein like 1 2.04992
LGMN legumain 2.04955
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 2.0448
PHLDA3 pleckstrin homology-like domain, family A, member 3 2.04315
FAT4 FAT atypical cadherin 4 2.03935
GFI1 growth factor independent 1 transcription repressor 2.0383
PCSK5 proprotein convertase subtilisin/kexin type 5 2.0377
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 2.03705
GPR65 G protein-coupled receptor 65 2.0333
DEFA4 defensin, alpha 4, corticostatin 2.03185
ARHGAP12 Rho GTPase activating protein 12 2.03085
NCALD neurocalcin delta 2.0302
NDRG1 N-myc downstream regulated 1 2.0292
IL25 interleukin 25 2.0286
FERRY3 FERRY endosomal RAB5 effector complex subunit 3 2.0283
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 2.0266
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 2.0241
DVL3 dishevelled segment polarity protein 3 2.0234
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 2.02103
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.0204
KAT6B K(lysine) acetyltransferase 6B 2.01945
ACAN aggrecan 2.0185
CYCS cytochrome c, somatic 2.0182
CHAMP1 chromosome alignment maintaining phosphoprotein 1 2.0181
DENND1A DENN/MADD domain containing 1A 2.0176
GCLM glutamate-cysteine ligase, modifier subunit 2.0142
TRIP4 thyroid hormone receptor interactor 4 2.01405
TCP11L1 t-complex 11, testis-specific-like 1 2.00997
MC3R melanocortin 3 receptor 2.00955
TPSD1 tryptase delta 1 2.0093
CRABP1 cellular retinoic acid binding protein 1 2.0054
ZNF23 zinc finger protein 23 2.0048
CLTC clathrin, heavy chain (Hc) 2.0047

decreased expression

Symbol Name Standardized Value
PCCB propionyl CoA carboxylase, beta polypeptide -10.0
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -9.6425
TRAP1 TNF receptor-associated protein 1 -7.61395
B4GAT1 beta-1,4-glucuronyltransferase 1 -6.7872
COG2 component of oligomeric golgi complex 2 -6.6644
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -5.70445
PECR peroxisomal trans-2-enoyl-CoA reductase -5.5625
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -5.5445
TOP2A topoisomerase (DNA) II alpha 170kDa -5.0605
PGM1 phosphoglucomutase 1 -5.0208
FGFR4 fibroblast growth factor receptor 4 -5.01885
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -5.0017
RPS4Y1 ribosomal protein S4, Y-linked 1 -5.0
INTS3 integrator complex subunit 3 -4.89615
STAMBP STAM binding protein -4.83465
ISOC1 isochorismatase domain containing 1 -4.79875
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -4.6799
LOC124907782 dual specificity protein phosphatase 22 -4.6428
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -4.61045
ARID5B AT rich interactive domain 5B (MRF1-like) -4.6091
HADH hydroxyacyl-CoA dehydrogenase -4.50882
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -4.3899
NNT nicotinamide nucleotide transhydrogenase -4.36658
HMGA2 high mobility group AT-hook 2 -4.242
DNM1L dynamin 1-like -4.20225
S100A4 S100 calcium binding protein A4 -4.14135
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -4.0867
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -4.0142
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.98445
MAP7 microtubule-associated protein 7 -3.93717
STK25 serine/threonine kinase 25 -3.8695
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -3.84745
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -3.81455
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.6846
GNAS GNAS complex locus -3.63119
COG7 component of oligomeric golgi complex 7 -3.62545
PSRC1 proline/serine-rich coiled-coil 1 -3.6196
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -3.6044
C2CD5 C2 calcium-dependent domain containing 5 -3.5896
NUP85 nucleoporin 85kDa -3.5609
LBR lamin B receptor -3.54565
PROS1 protein S (alpha) -3.54335
CD320 CD320 molecule -3.5239
AZGP1 alpha-2-glycoprotein 1, zinc-binding -3.5222
STMN1 stathmin 1 -3.4968
HDAC6 histone deacetylase 6 -3.48552
WASHC4 WASH complex subunit 4 -3.47728
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -3.47635
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -3.4694
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -3.43495
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -3.43037
TSPAN4 tetraspanin 4 -3.42858
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -3.40945
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -3.40173
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.38223
UBE2C ubiquitin-conjugating enzyme E2C -3.2901
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 -3.27342
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) -3.24105
DPH2 DPH2 homolog (S. cerevisiae) -3.2378
OXA1L oxidase (cytochrome c) assembly 1-like -3.2306
CCNA2 cyclin A2 -3.191
PARP2 poly (ADP-ribose) polymerase 2 -3.1809
NISCH nischarin -3.144
RPIA ribose 5-phosphate isomerase A -3.127
NT5DC2 5'-nucleotidase domain containing 2 -3.08935
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -3.0591
CDK4 cyclin-dependent kinase 4 -3.05905
INSIG1 insulin induced gene 1 -3.0541
DCK deoxycytidine kinase -3.0362
SIAH2 siah E3 ubiquitin protein ligase 2 -3.01485
TCEAL4 transcription elongation factor A (SII)-like 4 -2.98425
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 -2.9196
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -2.9167
NUDCD3 NudC domain containing 3 -2.89252
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa -2.8746
TRAPPC8 trafficking protein particle complex 8 -2.86765
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle -2.86225
DMAC2L distal membrane arm assembly component 2 like -2.81698
RAP1GAP2 RAP1 GTPase activating protein 2 -2.80135
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.8004
PIGN phosphatidylinositol glycan anchor biosynthesis, class N -2.7736
TSPAN6 tetraspanin 6 -2.76605
MED28 mediator complex subunit 28 -2.7589
KIF14 kinesin family member 14 -2.7521
GRWD1 glutamate-rich WD repeat containing 1 -2.7519
DDB2 damage-specific DNA binding protein 2, 48kDa -2.7114
SLC66A2 solute carrier family 66 member 2 -2.7049
ZNF692 zinc finger protein 692 -2.69995
MYH10 myosin, heavy chain 10, non-muscle -2.67633
CEMIP2 cell migration inducing hyaluronidase 2 -2.6741
IGFBP7 insulin-like growth factor binding protein 7 -2.6732
UBE3C ubiquitin protein ligase E3C -2.6714
RFC2 replication factor C (activator 1) 2, 40kDa -2.66803
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.66553
HOXA10-HOXA9 HOXA10-HOXA9 readthrough -2.65855
BLMH bleomycin hydrolase -2.65625
IQGAP2 IQ motif containing GTPase activating protein 2 -2.6485
GFUS GDP-L-fucose synthase -2.63777
ITGB1BP1 integrin beta 1 binding protein 1 -2.59888
PYCR1 pyrroline-5-carboxylate reductase 1 -2.5959
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -2.5774
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -2.5525
GET1 guided entry of tail-anchored proteins factor 1 -2.55035
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -2.5499
ESD esterase D -2.5483
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -2.54635
TTC31 tetratricopeptide repeat domain 31 -2.54515
FOS FBJ murine osteosarcoma viral oncogene homolog -2.5402
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa -2.5365
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -2.5284
PFAS phosphoribosylformylglycinamidine synthase -2.4971
USP1 ubiquitin specific peptidase 1 -2.49697
CTSL cathepsin L -2.49145
GCAT glycine C-acetyltransferase -2.48353
MAT1A methionine adenosyltransferase I, alpha -2.48305
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -2.47885
MSN moesin -2.4714
PCYT2 phosphate cytidylyltransferase 2, ethanolamine -2.468
PNKP polynucleotide kinase 3'-phosphatase -2.4645
GTF2H5 general transcription factor IIH, polypeptide 5 -2.42935
ENOPH1 enolase-phosphatase 1 -2.42035
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B -2.4201
ATP5ME ATP synthase membrane subunit e -2.41703
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta -2.4119
TSEN2 TSEN2 tRNA splicing endonuclease subunit -2.40075
TFDP1 transcription factor Dp-1 -2.39505
UBL5 ubiquitin-like 5 -2.39015
HDAC2 histone deacetylase 2 -2.3846
DBNDD2 dysbindin (dystrobrevin binding protein 1) domain containing 2 -2.38125
TMEM184C transmembrane protein 184C -2.36675
MSMO1 methylsterol monooxygenase 1 -2.35095
MRPL19 mitochondrial ribosomal protein L19 -2.3388
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 -2.32685
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 -2.32485
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) -2.32425
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 -2.3108
ADGRA3 adhesion G protein-coupled receptor A3 -2.30865
NUBPL nucleotide binding protein-like -2.30605
POLL polymerase (DNA directed), lambda -2.30575
DHRS1 dehydrogenase/reductase (SDR family) member 1 -2.3053
NDUFAF3 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 -2.30335
C8A complement component 8, alpha polypeptide -2.29375
GTF2A1 general transcription factor IIA, 1, 19/37kDa -2.2851
RPS5 ribosomal protein S5 -2.28255
RNF130 ring finger protein 130 -2.2824
EVL Enah/Vasp-like -2.2703
MRPS16 mitochondrial ribosomal protein S16 -2.2696
TPGS2 tubulin polyglutamylase complex subunit 2 -2.26648
BCHE butyrylcholinesterase -2.2544
ECHDC2 enoyl CoA hydratase domain containing 2 -2.24505
NDEL1 nudE neurodevelopment protein 1-like 1 -2.24405
GLOD4 glyoxalase domain containing 4 -2.2428
ASGR1 asialoglycoprotein receptor 1 -2.23345
AASS aminoadipate-semialdehyde synthase -2.23125
MACROD1 MACRO domain containing 1 -2.23065
STAP2 signal transducing adaptor family member 2 -2.23015
PRAF2 PRA1 domain family, member 2 -2.22195
NRIP1 nuclear receptor interacting protein 1 -2.21815
CDK20 cyclin-dependent kinase 20 -2.2125
LIPC lipase, hepatic -2.21075
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -2.2055
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 -2.2021
AHCY adenosylhomocysteinase -2.2002
NOP53 NOP53 ribosome biogenesis factor -2.1994
ALG8 ALG8, alpha-1,3-glucosyltransferase -2.19785
MCUB mitochondrial calcium uniporter dominant negative subunit beta -2.1897
ERC2 ELKS/RAB6-interacting/CAST family member 2 -2.18398
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.17735
MOCS2 molybdenum cofactor synthesis 2 -2.1767
SLC35F2 solute carrier family 35, member F2 -2.17155
PLK1 polo-like kinase 1 -2.16615
CRYL1 crystallin, lambda 1 -2.16285
CDKN2A cyclin-dependent kinase inhibitor 2A -2.15717
WNT7A wingless-type MMTV integration site family, member 7A -2.15645
NSG1 neuron specific gene family member 1 -2.1466
TUBA3E tubulin, alpha 3e -2.1462
SCN5A sodium channel, voltage gated, type V alpha subunit -2.1461
TMEM258 transmembrane protein 258 -2.14205
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.13615
GUCY1B1 guanylate cyclase 1 soluble subunit beta 1 -2.12745
DUSP6 dual specificity phosphatase 6 -2.12057
COMMD10 COMM domain containing 10 -2.1125
HEBP1 heme binding protein 1 -2.11175
ZMYND10 zinc finger, MYND-type containing 10 -2.10572
KDM5D lysine (K)-specific demethylase 5D -2.10205
LTA4H leukotriene A4 hydrolase -2.10155
NFIL3 nuclear factor, interleukin 3 regulated -2.09825
TBC1D31 TBC1 domain family, member 31 -2.09785
NENF neudesin neurotrophic factor -2.09785
MYG1 MYG1 exonuclease -2.0977
SDR39U1 short chain dehydrogenase/reductase family 39U, member 1 -2.0969
E2F8 E2F transcription factor 8 -2.0954
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.09415
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -2.0891
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 -2.08707
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) -2.08195
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -2.0758
GAMT guanidinoacetate N-methyltransferase -2.07455
MAGT1 magnesium transporter 1 -2.07195
ICAM2 intercellular adhesion molecule 2 -2.07175
ERGIC2 ERGIC and golgi 2 -2.0705
SPTAN1 spectrin, alpha, non-erythrocytic 1 -2.06652
FKBP3 FK506 binding protein 3, 25kDa -2.0635
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2 -2.05675
MRPL42 mitochondrial ribosomal protein L42 -2.0551
TRIM13 tripartite motif containing 13 -2.05295
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.0494
TCTN1 tectonic family member 1 -2.04475
MREG melanoregulin -2.03525
WSB1 WD repeat and SOCS box containing 1 -2.03475
HPX hemopexin -2.03013
LYRM2 LYR motif containing 2 -2.0263
NCAPG2 non-SMC condensin II complex, subunit G2 -2.02345
GMCL1 germ cell-less, spermatogenesis associated 1 -2.02115
ZMYM3 zinc finger, MYM-type 3 -2.0183
CDC73 cell division cycle 73 -2.01495
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 -2.0093
GYS2 glycogen synthase 2 (liver) -2.00515