| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | quinapril 5.37 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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66 genes differentially expressed following the CRCGN011_HEPG2_24H:G21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABHD6 | abhydrolase domain containing 6 | 8.2467 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.27635 |
| IDE | insulin-degrading enzyme | 4.7388 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 4.7285 |
| PRKCQ | protein kinase C, theta | 4.60273 |
| ZNF589 | zinc finger protein 589 | 4.56667 |
| STIMATE | STIM activating enhancer | 4.4089 |
| LCN2 | lipocalin 2 | 4.38115 |
| RRAGA | Ras-related GTP binding A | 4.1157 |
| EPHA3 | EPH receptor A3 | 4.06478 |
| GSTZ1 | glutathione S-transferase zeta 1 | 4.0585 |
| TXNL4B | thioredoxin-like 4B | 3.1928 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.0812 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 2.9902 |
| FZD7 | frizzled class receptor 7 | 2.76312 |
| NMU | neuromedin U | 2.75835 |
| HSPA1A | heat shock 70kDa protein 1A | 2.7173 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 2.6812 |
| JADE2 | jade family PHD finger 2 | 2.66072 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 2.60755 |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha | 2.5053 |
| KLHL9 | kelch-like family member 9 | 2.45937 |
| LCE2B | late cornified envelope 2B | 2.39885 |
| PLSCR3 | phospholipid scramblase 3 | 2.33573 |
| CEP57 | centrosomal protein 57kDa | 2.29807 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.20705 |
| ARL4A | ADP-ribosylation factor-like 4A | 2.04615 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 2.04607 |
| SNAP29 | synaptosomal-associated protein, 29kDa | 2.02915 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 2.01 |
| HOOK2 | hook microtubule-tethering protein 2 | 2.0079 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GNAS | GNAS complex locus | -7.35928 |
| CCNB2 | cyclin B2 | -6.59285 |
| LDHD | lactate dehydrogenase D | -5.52865 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -5.0 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.86495 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -4.7564 |
| CDC20 | cell division cycle 20 | -4.66275 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.43875 |
| MAP7 | microtubule-associated protein 7 | -4.40997 |
| TUBB6 | tubulin, beta 6 class V | -4.32185 |
| TLCD3A | TLC domain containing 3A | -4.14105 |
| WDR7 | WD repeat domain 7 | -3.7289 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.62302 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.58085 |
| PCNA | proliferating cell nuclear antigen | -3.5076 |
| RNF167 | ring finger protein 167 | -3.3722 |
| TBC1D31 | TBC1 domain family, member 31 | -3.1653 |
| VDAC1 | voltage-dependent anion channel 1 | -3.0619 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.85395 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.80128 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.74878 |
| TRAP1 | TNF receptor-associated protein 1 | -2.68235 |
| ZNF586 | zinc finger protein 586 | -2.46345 |
| ADI1 | acireductone dioxygenase 1 | -2.43665 |
| NDRG4 | NDRG family member 4 | -2.3994 |
| PLXNB3 | plexin B3 | -2.29435 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.25055 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -2.21275 |
| EGFL6 | EGF-like-domain, multiple 6 | -2.17815 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 | -2.12175 |
| SNX11 | sorting nexin 11 | -2.0989 |
| OXR1 | oxidation resistance 1 | -2.07165 |
| SIGLEC5 | sialic acid binding Ig-like lectin 5 | -2.05815 |
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | -2.0145 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | -2.01043 |
