CRCGN011_HEPG2_24H:G24 Gene Set
Genes
41 genes differentially expressed following the CRCGN011_HEPG2_24H:G24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
10.0
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
5.8047
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
5.1829
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
5.0423
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.95215
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.6238
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
3.50515
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.7391
|
|
EVL
|
Enah/Vasp-like
|
2.59955
|
|
NUP133
|
nucleoporin 133kDa
|
2.40335
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.37745
|
|
GATA2
|
GATA binding protein 2
|
2.30465
|
|
GPATCH8
|
G patch domain containing 8
|
2.25268
|
|
KLHL9
|
kelch-like family member 9
|
2.19097
|
|
HBD
|
hemoglobin, delta
|
2.1714
|
|
EIF2B5
|
eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
|
2.10945
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
2.0794
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
2.0409
|
|
TPST2
|
tyrosylprotein sulfotransferase 2
|
2.0211
|
|
PEX11B
|
peroxisomal biogenesis factor 11 beta
|
2.00995
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-7.4362
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-5.64715
|
|
LDHD
|
lactate dehydrogenase D
|
-4.9891
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.7116
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.66275
|
|
CDC20
|
cell division cycle 20
|
-4.66275
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
-4.51255
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.8776
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
-3.75895
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.6465
|
|
GNAS
|
GNAS complex locus
|
-3.37394
|
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
-3.0018
|
|
SOAT2
|
sterol O-acyltransferase 2
|
-2.57075
|
|
WASHC4
|
WASH complex subunit 4
|
-2.43233
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.36678
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.2477
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.20222
|
|
SERPINA1
|
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
|
-2.10445
|
|
TACR1
|
tachykinin receptor 1
|
-2.08395
|
|
STMN1
|
stathmin 1
|
-2.01265
|
|
PGR
|
progesterone receptor
|
-2.0046
|
