CRCGN011_HEPG2_24H:H02 Gene Set
Genes
50 genes differentially expressed following the CRCGN011_HEPG2_24H:H02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
5.7517
|
|
UBQLN2
|
ubiquilin 2
|
5.2403
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
5.16685
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.97145
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
4.5824
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
4.1887
|
|
MTHFD2
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
|
3.98455
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.5112
|
|
LOC122526780
|
uncharacterized LOC122526780
|
3.29895
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
2.955
|
|
DHDDS
|
dehydrodolichyl diphosphate synthase
|
2.88532
|
|
PLS1
|
plastin 1
|
2.6088
|
|
FASTKD5
|
FAST kinase domains 5
|
2.54485
|
|
TEX10
|
testis expressed 10
|
2.48875
|
|
ZNF589
|
zinc finger protein 589
|
2.47815
|
|
TXNRD1
|
thioredoxin reductase 1
|
2.46775
|
|
PHKA1
|
phosphorylase kinase, alpha 1 (muscle)
|
2.34465
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.31445
|
|
HMGA2
|
high mobility group AT-hook 2
|
2.11265
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.0801
|
|
CTNNAL1
|
catenin (cadherin-associated protein), alpha-like 1
|
2.02405
|
|
CALU
|
calumenin
|
2.00696
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
USP6NL
|
USP6 N-terminal like
|
-5.9618
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-5.38075
|
|
DNM1L
|
dynamin 1-like
|
-5.2887
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.86965
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.8322
|
|
TCTN1
|
tectonic family member 1
|
-4.42355
|
|
LDHD
|
lactate dehydrogenase D
|
-4.3978
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-4.3258
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-4.14695
|
|
GNAS
|
GNAS complex locus
|
-3.59586
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-3.57902
|
|
CCNB2
|
cyclin B2
|
-3.4704
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
-3.3555
|
|
FDFT1
|
farnesyl-diphosphate farnesyltransferase 1
|
-3.10442
|
|
WASHC4
|
WASH complex subunit 4
|
-3.01288
|
|
ALDOC
|
aldolase C, fructose-bisphosphate
|
-2.955
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.71292
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.68215
|
|
MYL9
|
myosin, light chain 9, regulatory
|
-2.619
|
|
SOAT2
|
sterol O-acyltransferase 2
|
-2.3067
|
|
ID2
|
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
|
-2.28895
|
|
PSMC5
|
proteasome (prosome, macropain) 26S subunit, ATPase, 5
|
-2.18505
|
|
HIC1
|
hypermethylated in cancer 1
|
-2.1223
|
|
BEAN1
|
brain expressed, associated with NEDD4, 1
|
-2.1213
|
|
SCAND1
|
SCAN domain containing 1
|
-2.0818
|
|
PEG10
|
paternally expressed 10
|
-2.07743
|
|
LRFN3
|
leucine rich repeat and fibronectin type III domain containing 3
|
-2.07105
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.0102
|
