CRCGN011_HEPG2_24H:H07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description doxylamine 40.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

475 genes differentially expressed following the CRCGN011_HEPG2_24H:H07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
NMU neuromedin U 10.0
BACE2 beta-site APP-cleaving enzyme 2 10.0
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 9.8093
BPHL biphenyl hydrolase-like (serine hydrolase) 8.1815
WDR7 WD repeat domain 7 7.9876
SHB Src homology 2 domain containing adaptor protein B 7.8378
MEST mesoderm specific transcript 7.7068
LCN2 lipocalin 2 7.6561
CYCS cytochrome c, somatic 7.3305
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta 6.98175
TESK1 testis-specific kinase 1 6.5397
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 6.315
PTK2 protein tyrosine kinase 2 5.71665
TENT4A terminal nucleotidyltransferase 4A 5.714
RAB21 RAB21, member RAS oncogene family 5.4017
H2BC12 H2B clustered histone 12 5.2331
MMP2 matrix metallopeptidase 2 4.8375
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 4.2256
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 4.2125
GARRE1 granule associated Rac and RHOG effector 1 4.1546
CHN1 chimerin 1 4.1068
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae) 3.916
PARP2 poly (ADP-ribose) polymerase 2 3.84333
NR1H2 nuclear receptor subfamily 1, group H, member 2 3.5898
PPP1R13B protein phosphatase 1, regulatory subunit 13B 3.5352
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 3.4689
NSDHL NAD(P) dependent steroid dehydrogenase-like 3.4139
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 3.3794
ZNF623 zinc finger protein 623 3.3026
FKBP4 FK506 binding protein 4, 59kDa 3.28405
UBE2L6 ubiquitin-conjugating enzyme E2L 6 3.2563
PCGF2 polycomb group ring finger 2 3.2552
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 3.2411
EHMT2 euchromatic histone-lysine N-methyltransferase 2 3.2387
ZNF74 zinc finger protein 74 3.2219
NIT1 nitrilase 1 3.2185
CDK12 cyclin-dependent kinase 12 3.21
ZNF318 zinc finger protein 318 3.1784
SH3D19 SH3 domain containing 19 3.1672
EDN1 endothelin 1 3.167
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 3.1616
CD200 CD200 molecule 3.0913
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha 3.05355
STMN3 stathmin-like 3 3.0331
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 3.0263
RGPD1 RANBP2-like and GRIP domain containing 1 3.0043
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.9892
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 2.9862
PRR15L proline rich 15-like 2.9796
TLN1 talin 1 2.9746
OGN osteoglycin 2.9645
NOSIP nitric oxide synthase interacting protein 2.9377
SGCE sarcoglycan, epsilon 2.9065
MTERF4 mitochondrial transcription termination factor 4 2.8987
SMIM40 small integral membrane protein 40 2.8887
ZKSCAN4 zinc finger with KRAB and SCAN domains 4 2.8867
CCL17 chemokine (C-C motif) ligand 17 2.866
ANXA11 annexin A11 2.85305
ANKRD10 ankyrin repeat domain 10 2.8278
PPP1R16B protein phosphatase 1, regulatory subunit 16B 2.77075
RIPK4 receptor-interacting serine-threonine kinase 4 2.77
OXCT1 3-oxoacid CoA transferase 1 2.7607
SCGB2A1 secretoglobin, family 2A, member 1 2.7558
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 2.7502
ATP11B ATPase, class VI, type 11B 2.7442
H2BC21 H2B clustered histone 21 2.7367
ZNF589 zinc finger protein 589 2.7318
TEX10 testis expressed 10 2.7286
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 2.7215
TCEA2 transcription elongation factor A (SII), 2 2.7168
POLD1 polymerase (DNA directed), delta 1, catalytic subunit 2.7081
SYNPO synaptopodin 2.7079
FCHO1 FCH domain only 1 2.7077
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 2.6999
FAIM Fas apoptotic inhibitory molecule 2.6968
H2BC9 H2B clustered histone 9 2.6892
NCKIPSD NCK interacting protein with SH3 domain 2.684
FAN1 FANCD2/FANCI-associated nuclease 1 2.6749
MOCS1 molybdenum cofactor synthesis 1 2.6477
NPR1 natriuretic peptide receptor 1 2.6196
PANK4 pantothenate kinase 4 2.6015
GJD3 gap junction protein, delta 3, 31.9kDa 2.5787
FANCG Fanconi anemia, complementation group G 2.577
SH2B2 SH2B adaptor protein 2 2.5758
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound 2.5711
CIAO3 cytosolic iron-sulfur assembly component 3 2.5706
TEP1 telomerase-associated protein 1 2.5487
ZNF813 zinc finger protein 813 2.5459
SLC26A6 solute carrier family 26 (anion exchanger), member 6 2.533
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 2.5275
IFNAR1 interferon (alpha, beta and omega) receptor 1 2.5258
PDE2A phosphodiesterase 2A, cGMP-stimulated 2.5188
ZNF551 zinc finger protein 551 2.5158
COQ9 coenzyme Q9 2.5014
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 2.5011
CREB3L4 cAMP responsive element binding protein 3-like 4 2.4929
AUH AU RNA binding protein/enoyl-CoA hydratase 2.4903
RGCC regulator of cell cycle 2.4754
ZSCAN26 zinc finger and SCAN domain containing 26 2.4637
SCCPDH saccharopine dehydrogenase (putative) 2.4593
ZNF304 zinc finger protein 304 2.457
ACIN1 apoptotic chromatin condensation inducer 1 2.4468
RBM41 RNA binding motif protein 41 2.445
JCAD junctional cadherin 5 associated 2.4411
APOBR apolipoprotein B receptor 2.4408
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 2.4376
FMO1 flavin containing monooxygenase 1 2.4362
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 2.4266
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 2.4146
LUM lumican 2.414
ATP5MC3 ATP synthase membrane subunit c locus 3 2.41135
GHITM growth hormone inducible transmembrane protein 2.4081
PNLIPRP2 pancreatic lipase-related protein 2 2.4037
TSPAN15 tetraspanin 15 2.3972
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 2.3929
MKNK1 MAP kinase interacting serine/threonine kinase 1 2.388
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 2.3848
TBC1D15 TBC1 domain family, member 15 2.3805
STAU2 staufen double-stranded RNA binding protein 2 2.3792
WASHC5 WASH complex subunit 5 2.3727
ZNF227 zinc finger protein 227 2.3717
RPAP2 RNA polymerase II associated protein 2 2.3691
CLEC10A C-type lectin domain family 10, member A 2.3654
ECD ecdysoneless homolog (Drosophila) 2.3627
MSLN mesothelin 2.3585
ANKMY2 ankyrin repeat and MYND domain containing 2 2.3546
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G 2.3546
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 2.3479
SOBP sine oculis binding protein homolog (Drosophila) 2.3445
LASP1 LIM and SH3 protein 1 2.3402
PIGB phosphatidylinositol glycan anchor biosynthesis, class B 2.3373
ZNF37A zinc finger protein 37A 2.3252
DDN dendrin 2.3196
SLC19A3 solute carrier family 19 (thiamine transporter), member 3 2.3157
CDH5 cadherin 5, type 2 (vascular endothelium) 2.3067
CTNND1 catenin (cadherin-associated protein), delta 1 2.30237
CRABP2 cellular retinoic acid binding protein 2 2.3017
RPUSD2 RNA pseudouridylate synthase domain containing 2 2.2982
MXI1 MAX interactor 1, dimerization protein 2.295
SOX18 SRY (sex determining region Y)-box 18 2.2944
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 2.2905
ZNF804A zinc finger protein 804A 2.2834
MEIS2 Meis homeobox 2 2.2806
HAND1 heart and neural crest derivatives expressed 1 2.2776
PDE5A phosphodiesterase 5A, cGMP-specific 2.2765
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 2.2713
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa 2.267
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 2.2654
PHACTR1 phosphatase and actin regulator 1 2.2653
PTPRF protein tyrosine phosphatase, receptor type, F 2.26493
DIPK1A divergent protein kinase domain 1A 2.264
AMOTL2 angiomotin like 2 2.2586
CDK5 cyclin-dependent kinase 5 2.2575
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 2.2551
H2BC4 H2B clustered histone 4 2.25442
TERF2 telomeric repeat binding factor 2 2.2544
NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 2.2528
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.2501
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 2.2468
KLRF1 killer cell lectin-like receptor subfamily F, member 1 2.2458
ZNF549 zinc finger protein 549 2.2398
RGS18 regulator of G-protein signaling 18 2.2355
AKAP5 A kinase (PRKA) anchor protein 5 2.2354
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 2.23515
MSANTD3-TMEFF1 MSANTD3-TMEFF1 readthrough 2.235
WDR46 WD repeat domain 46 2.2344
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 2.2322
MRC1 mannose receptor, C type 1 2.2312
TLX2 T-cell leukemia homeobox 2 2.2259
JADE3 jade family PHD finger 3 2.2238
PLEKHO1 pleckstrin homology domain containing, family O member 1 2.221
GPC1 glypican 1 2.2201
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 2.2192
WT1 Wilms tumor 1 2.21695
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 2.21393
SLC6A16 solute carrier family 6, member 16 2.2107
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 2.1972
MAGEB2 melanoma antigen family B2 2.1937
DHRS11 dehydrogenase/reductase (SDR family) member 11 2.1937
ITPKA inositol-trisphosphate 3-kinase A 2.1932
CNOT3 CCR4-NOT transcription complex, subunit 3 2.1839
RLN1 relaxin 1 2.1785
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 2.1741
WDR76 WD repeat domain 76 2.1692
ITPKB inositol-trisphosphate 3-kinase B 2.1683
PEDS1 plasmanylethanolamine desaturase 1 2.1655
GRHPR glyoxylate reductase/hydroxypyruvate reductase 2.15887
PRKCI protein kinase C, iota 2.1587
STXBP2 syntaxin binding protein 2 2.1517
FAM149B1 family with sequence similarity 149, member B1 2.15147
IL1B interleukin 1, beta 2.14965
HSPA12A heat shock 70kDa protein 12A 2.1455
BNC2 basonuclin 2 2.1446
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 2.1372
UBAP2 ubiquitin associated protein 2 2.13415
MSRA methionine sulfoxide reductase A 2.1337
ZNF234 zinc finger protein 234 2.131
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 2.12527
MTAP methylthioadenosine phosphorylase 2.12237
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 2.1221
EML1 echinoderm microtubule associated protein like 1 2.1199
ZNF224 zinc finger protein 224 2.1173
B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 2.1163
PLAAT2 phospholipase A and acyltransferase 2 2.1115
CAMK4 calcium/calmodulin-dependent protein kinase IV 2.1012
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 2.0983
EMCN endomucin 2.093
EPS8L1 EPS8-like 1 2.08946
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial 2.0891
KRT4 keratin 4, type II 2.0886
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 2.08755
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 2.0874
NHLH2 nescient helix loop helix 2 2.0859
ANO3 anoctamin 3 2.0831
VAC14 Vac14 homolog (S. cerevisiae) 2.0822
MUC16 mucin 16, cell surface associated 2.082
ISYNA1 inositol-3-phosphate synthase 1 2.0792
ADRB2 adrenoceptor beta 2, surface 2.0776
TDRD3 tudor domain containing 3 2.07525
ARF3 ADP-ribosylation factor 3 2.07503
ZBTB5 zinc finger and BTB domain containing 5 2.074
ZNF232 zinc finger protein 232 2.0692
ZNF141 zinc finger protein 141 2.0662
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 2.0641
ZNF331 zinc finger protein 331 2.0636
AKAP1 A kinase (PRKA) anchor protein 1 2.06142
ZNF112 zinc finger protein 112 2.0602
SFRP1 secreted frizzled-related protein 1 2.05907
CCL2 chemokine (C-C motif) ligand 2 2.0588
GSR glutathione reductase 2.0574
ALG12 ALG12, alpha-1,6-mannosyltransferase 2.055
WDR33 WD repeat domain 33 2.0509
RNF5 ring finger protein 5, E3 ubiquitin protein ligase 2.0458
AOC3 amine oxidase, copper containing 3 2.0436
MAVS mitochondrial antiviral signaling protein 2.0435
CPAMD8 C3 and PZP-like, alpha-2-macroglobulin domain containing 8 2.0419
DYNLT3 dynein, light chain, Tctex-type 3 2.0412
PLCL1 phospholipase C-like 1 2.0411
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 2.0317
H1-2 H1.2 linker histone, cluster member 2.0313
LRPPRC leucine-rich pentatricopeptide repeat containing 2.03055
CPA2 carboxypeptidase A2 (pancreatic) 2.0294
FAM200C family with sequence similarity 200 member C 2.0287
FABP3 fatty acid binding protein 3, muscle and heart 2.02295
NUAK1 NUAK family, SNF1-like kinase, 1 2.0125
LYN LYN proto-oncogene, Src family tyrosine kinase 2.01133
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 2.011
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 2.0103
DUSP28 dual specificity phosphatase 28 2.0097
TUBG1 tubulin, gamma 1 2.0095
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17 2.0094
KLHL22 kelch-like family member 22 2.00857
COL1A2 collagen, type I, alpha 2 2.00815
GINS4 GINS complex subunit 4 (Sld5 homolog) 2.0081
PLXNA1 plexin A1 2.00655
CLSTN3 calsyntenin 3 2.0059
HLA-DRA major histocompatibility complex, class II, DR alpha 2.0037
SIRT4 sirtuin 4 2.00265
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like 2.0014

decreased expression

Symbol Name Standardized Value
TLCD3A TLC domain containing 3A -9.3195
MAP7 microtubule-associated protein 7 -8.72843
CD320 CD320 molecule -8.41
TCTN1 tectonic family member 1 -8.3299
TES testin LIM domain protein -6.24855
SPAG4 sperm associated antigen 4 -6.2051
HEATR1 HEAT repeat containing 1 -6.06685
SYNGAP1 synaptic Ras GTPase activating protein 1 -6.0478
CSNK1E casein kinase 1, epsilon -5.822
CASP7 caspase 7, apoptosis-related cysteine peptidase -5.6719
FBXL12 F-box and leucine-rich repeat protein 12 -5.5583
NRIP1 nuclear receptor interacting protein 1 -5.3698
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -5.1589
C5 complement component 5 -5.1429
WASHC4 WASH complex subunit 4 -4.92497
PRPF4 pre-mRNA processing factor 4 -4.8528
SLC35F2 solute carrier family 35, member F2 -4.7951
GLOD4 glyoxalase domain containing 4 -4.7634
PSRC1 proline/serine-rich coiled-coil 1 -4.4694
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -4.4463
CHIC2 cysteine-rich hydrophobic domain 2 -4.2833
TCEAL4 transcription elongation factor A (SII)-like 4 -4.1781
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -3.9367
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -3.8343
CCDC90B coiled-coil domain containing 90B -3.758
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 -3.6686
GPSM2 G-protein signaling modulator 2 -3.51095
AURKA aurora kinase A -3.35445
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -3.146
MVP major vault protein -3.1172
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 -3.0974
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -3.0963
GET1 guided entry of tail-anchored proteins factor 1 -3.0941
UBL5 ubiquitin-like 5 -3.0903
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1 -3.006
ARID4B AT rich interactive domain 4B (RBP1-like) -2.9911
TMED1 transmembrane emp24 protein transport domain containing 1 -2.9787
BDH1 3-hydroxybutyrate dehydrogenase, type 1 -2.9695
LIPC lipase, hepatic -2.9503
CLBA1 clathrin binding box of aftiphilin containing 1 -2.9177
EIF5 eukaryotic translation initiation factor 5 -2.89912
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 -2.8793
NLRP4 NLR family, pyrin domain containing 4 -2.8156
SRSF8 serine/arginine-rich splicing factor 8 -2.80385
LYRM1 LYR motif containing 1 -2.7972
TFE3 transcription factor binding to IGHM enhancer 3 -2.7658
JPT2 Jupiter microtubule associated homolog 2 -2.74597
ARID4A AT rich interactive domain 4A (RBP1-like) -2.7164
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide -2.6929
TMEM126B transmembrane protein 126B -2.6766
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B -2.6608
UBE4A ubiquitination factor E4A -2.6491
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -2.6456
PEF1 penta-EF-hand domain containing 1 -2.6413
RAB11FIP5 RAB11 family interacting protein 5 (class I) -2.6298
PRELID3A PRELI domain containing 3A -2.6241
REEP4 receptor accessory protein 4 -2.6181
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A -2.5991
TSHB thyroid stimulating hormone, beta -2.5925
METTL9 methyltransferase like 9 -2.5896
CAB39 calcium binding protein 39 -2.5872
ELL2 elongation factor, RNA polymerase II, 2 -2.5865
PZP pregnancy-zone protein -2.5849
CDKN2A cyclin-dependent kinase inhibitor 2A -2.5661
ICAM3 intercellular adhesion molecule 3 -2.5581
FAM174B family with sequence similarity 174, member B -2.5575
SELENOF selenoprotein F -2.5546
YIPF1 Yip1 domain family, member 1 -2.5484
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 -2.52457
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -2.5129
PTCH2 patched 2 -2.5066
EED embryonic ectoderm development -2.50565
GLRA2 glycine receptor, alpha 2 -2.4993
STX1A syntaxin 1A (brain) -2.4953
PCCB propionyl CoA carboxylase, beta polypeptide -2.4953
C1QTNF3 C1q and tumor necrosis factor related protein 3 -2.4901
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 -2.4838
STMN1 stathmin 1 -2.482
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 -2.4778
SKIC2 SKI2 subunit of superkiller complex -2.4637
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -2.4449
HSPA14 heat shock 70kDa protein 14 -2.442
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -2.43555
C8B complement component 8, beta polypeptide -2.4262
TSLIG3A tRNA splicing ligase complex subunit 3A -2.426
FOXA2 forkhead box A2 -2.4214
THBD thrombomodulin -2.415
MYT1 myelin transcription factor 1 -2.4121
CD244 CD244 molecule, natural killer cell receptor 2B4 -2.411
KIF14 kinesin family member 14 -2.4062
TRIM9 tripartite motif containing 9 -2.3987
TSPAN3 tetraspanin 3 -2.39535
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase -2.3729
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -2.3682
LHX3 LIM homeobox 3 -2.3629
PDZD8 PDZ domain containing 8 -2.3579
HSPB1 heat shock 27kDa protein 1 -2.3565
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -2.3515
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 -2.3447
ATF5 activating transcription factor 5 -2.34415
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) -2.3372
HSPB2 heat shock 27kDa protein 2 -2.3368
DHRS7 dehydrogenase/reductase (SDR family) member 7 -2.3361
NOTCH2NLB notch 2 N-terminal like B -2.3143
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 -2.3106
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 -2.30997
APCS amyloid P component, serum -2.3086
FCGRT Fc fragment of IgG, receptor, transporter, alpha -2.3064
HPR haptoglobin-related protein -2.3052
GOLPH3 golgi phosphoprotein 3 (coat-protein) -2.3004
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 -2.2984
F9 coagulation factor IX -2.2978
TNIP1 TNFAIP3 interacting protein 1 -2.2938
NECTIN2 nectin cell adhesion molecule 2 -2.2903
SLC35B1 solute carrier family 35, member B1 -2.2895
OGFRL1 opioid growth factor receptor-like 1 -2.2882
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -2.2843
ATP8B4 ATPase, class I, type 8B, member 4 -2.2751
ATG2A autophagy related 2A -2.2741
PRMT3 protein arginine methyltransferase 3 -2.2694
ZNF267 zinc finger protein 267 -2.269
TMEM43 transmembrane protein 43 -2.2624
CFHR2 complement factor H-related 2 -2.258
NRIP3 nuclear receptor interacting protein 3 -2.2551
LONP2 lon peptidase 2, peroxisomal -2.25425
ASXL2 additional sex combs like transcriptional regulator 2 -2.2398
EMID1 EMI domain containing 1 -2.238
PRDX4 peroxiredoxin 4 -2.2351
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) -2.23265
BMP6 bone morphogenetic protein 6 -2.2304
TSPYL1 TSPY-like 1 -2.2297
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha -2.2252
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -2.22335
CERS1 ceramide synthase 1 -2.2153
APLNR apelin receptor -2.211
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 -2.2098
SASH1 SAM and SH3 domain containing 1 -2.20625
STOM stomatin -2.2031
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 -2.203
ACYP2 acylphosphatase 2, muscle type -2.1871
WDR6 WD repeat domain 6 -2.1825
YAF2 YY1 associated factor 2 -2.1752
MPPED1 metallophosphoesterase domain containing 1 -2.1749
TAOK1 TAO kinase 1 -2.1743
LY6G5C lymphocyte antigen 6 complex, locus G5C -2.1737
F5 coagulation factor V (proaccelerin, labile factor) -2.1725
RPL36 ribosomal protein L36 -2.1724
MAEA macrophage erythroblast attacher -2.1723
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 -2.1695
CHPF2 chondroitin polymerizing factor 2 -2.16475
CIRBP cold inducible RNA binding protein -2.16295
CCDC170 coiled-coil domain containing 170 -2.1586
BAALC brain and acute leukemia, cytoplasmic -2.1568
MRPL46 mitochondrial ribosomal protein L46 -2.1559
CST8 cystatin 8 (cystatin-related epididymal specific) -2.1558
HBQ1 hemoglobin, theta 1 -2.1545
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 -2.1542
SIVA1 SIVA1, apoptosis-inducing factor -2.1536
REEP5 receptor accessory protein 5 -2.1536
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4 -2.1503
E2F3 E2F transcription factor 3 -2.1469
NPC2 Niemann-Pick disease, type C2 -2.1466
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 -2.1411
DAO D-amino-acid oxidase -2.1385
LYPLA1 lysophospholipase I -2.13815
MNAT1 MNAT CDK-activating kinase assembly factor 1 -2.1371
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) -2.1348
BCAS1 breast carcinoma amplified sequence 1 -2.1266
FOXJ1 forkhead box J1 -2.1251
COQ10B coenzyme Q10 homolog B (S. cerevisiae) -2.1211
RBM14-RBM4 RBM14-RBM4 readthrough -2.1188
ETNPPL ethanolamine-phosphate phospho-lyase -2.117
F12 coagulation factor XII (Hageman factor) -2.1096
CASZ1 castor zinc finger 1 -2.1073
MYO6 myosin VI -2.10653
IGFLR1 IGF-like family receptor 1 -2.1065
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 -2.1049
CAMKMT calmodulin-lysine N-methyltransferase -2.1039
PMP2 peripheral myelin protein 2 -2.1023
ACSL6 acyl-CoA synthetase long-chain family member 6 -2.1023
STAB2 stabilin 2 -2.1017
SPX spexin hormone -2.1014
AQP4 aquaporin 4 -2.09742
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) -2.0925
FAM222B family with sequence similarity 222, member B -2.0827
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -2.08105
USP12 ubiquitin specific peptidase 12 -2.0801
FZD5 frizzled class receptor 5 -2.07845
DERA deoxyribose-phosphate aldolase (putative) -2.0784
FFAR2 free fatty acid receptor 2 -2.0774
FBXO2 F-box protein 2 -2.0769
NADSYN1 NAD synthetase 1 -2.0768
CDK4 cyclin-dependent kinase 4 -2.0567
CCL7 chemokine (C-C motif) ligand 7 -2.0486
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -2.0482
RPP25 ribonuclease P/MRP 25kDa subunit -2.0475
TM4SF4 transmembrane 4 L six family member 4 -2.0435
SAA4 serum amyloid A4, constitutive -2.0408
CETN1 centrin, EF-hand protein, 1 -2.0332
MRPS16 mitochondrial ribosomal protein S16 -2.0323
PIGT phosphatidylinositol glycan anchor biosynthesis, class T -2.0312
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1 -2.0293
DPY19L1 dpy-19-like 1 (C. elegans) -2.0272
ADGRE1 adhesion G protein-coupled receptor E1 -2.0261
RNF103 ring finger protein 103 -2.0256
CA10 carbonic anhydrase X -2.0245
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 -2.023
QSOX1 quiescin Q6 sulfhydryl oxidase 1 -2.0206
TMEM9B TMEM9 domain family, member B -2.013
LEFTY2 left-right determination factor 2 -2.0108
S100A11 S100 calcium binding protein A11 -2.0057
NSUN3 NOP2/Sun domain family, member 3 -2.0054
ACOT9 acyl-CoA thioesterase 9 -2.0043
YIPF2 Yip1 domain family, member 2 -2.0037
RFX2 regulatory factor X, 2 (influences HLA class II expression) -2.0036
STXBP3 syntaxin binding protein 3 -2.0003