| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | doxylamine 10.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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73 genes differentially expressed following the CRCGN011_HEPG2_24H:H09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPER1 | G protein-coupled estrogen receptor 1 | 6.46702 |
| NMU | neuromedin U | 5.77755 |
| CSK | c-src tyrosine kinase | 5.08485 |
| LCN2 | lipocalin 2 | 5.0 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.78525 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.64955 |
| RPL39L | ribosomal protein L39-like | 4.6355 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 4.52695 |
| MEST | mesoderm specific transcript | 4.2748 |
| TESK1 | testis-specific kinase 1 | 4.22375 |
| PRKCH | protein kinase C, eta | 3.83308 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 3.55875 |
| PTK2 | protein tyrosine kinase 2 | 3.52037 |
| LSR | lipolysis stimulated lipoprotein receptor | 3.11675 |
| LOC122526780 | uncharacterized LOC122526780 | 2.8609 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.84425 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 2.8236 |
| PIGB | phosphatidylinositol glycan anchor biosynthesis, class B | 2.73205 |
| ETAA1 | Ewing tumor-associated antigen 1 | 2.62295 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 2.6114 |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa | 2.57067 |
| RAB21 | RAB21, member RAS oncogene family | 2.5563 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 2.4775 |
| ZNF7 | zinc finger protein 7 | 2.32055 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 2.21645 |
| SMIM40 | small integral membrane protein 40 | 2.18555 |
| CBR3 | carbonyl reductase 3 | 2.1744 |
| CHPF | chondroitin polymerizing factor | 2.171 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 2.13455 |
| CEP57 | centrosomal protein 57kDa | 2.13077 |
| NVL | nuclear VCP-like | 2.11005 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | 2.0531 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | 2.0529 |
| H2BC21 | H2B clustered histone 21 | 2.03825 |
| DTWD1 | DTW domain containing 1 | 2.0064 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.0055 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UGDH | UDP-glucose 6-dehydrogenase | -5.6929 |
| HEATR1 | HEAT repeat containing 1 | -5.66507 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -5.23675 |
| CD320 | CD320 molecule | -5.0 |
| LDHD | lactate dehydrogenase D | -5.0 |
| PCNA | proliferating cell nuclear antigen | -4.9283 |
| MRPS2 | mitochondrial ribosomal protein S2 | -4.852 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.8353 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.66275 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.6063 |
| MAP7 | microtubule-associated protein 7 | -4.51118 |
| SLC35F2 | solute carrier family 35, member F2 | -3.9701 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -3.7587 |
| GNAS | GNAS complex locus | -3.63086 |
| GLOD4 | glyoxalase domain containing 4 | -3.49675 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -3.08637 |
| SNX11 | sorting nexin 11 | -2.76575 |
| EDC4 | enhancer of mRNA decapping 4 | -2.5537 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.50015 |
| LZTFL1 | leucine zipper transcription factor-like 1 | -2.49525 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.43187 |
| PHB1 | prohibitin 1 | -2.39003 |
| SIGLEC5 | sialic acid binding Ig-like lectin 5 | -2.35955 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.2485 |
| S1PR2 | sphingosine-1-phosphate receptor 2 | -2.2275 |
| TFCP2L1 | transcription factor CP2-like 1 | -2.1706 |
| CCL21 | chemokine (C-C motif) ligand 21 | -2.1647 |
| GET1 | guided entry of tail-anchored proteins factor 1 | -2.15705 |
| GGT5 | gamma-glutamyltransferase 5 | -2.14155 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.12867 |
| GCSH | glycine cleavage system protein H (aminomethyl carrier) | -2.09555 |
| ANKRD40 | ankyrin repeat domain 40 | -2.0773 |
| FSCN3 | fascin actin-bundling protein 3, testicular | -2.0573 |
| TSPO | translocator protein (18kDa) | -2.0471 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | -2.0463 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 | -2.0192 |
| NR1I2 | nuclear receptor subfamily 1, group I, member 2 | -2.01438 |
