| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | doxylamine 2.5 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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72 genes differentially expressed following the CRCGN011_HEPG2_24H:H11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NMU | neuromedin U | 5.23165 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.15955 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 5.08535 |
| MYLK | myosin light chain kinase | 4.6702 |
| LAGE3 | L antigen family, member 3 | 4.6279 |
| TLR4 | toll-like receptor 4 | 4.5542 |
| HDGFL3 | HDGF like 3 | 4.51886 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 3.82709 |
| ISOC1 | isochorismatase domain containing 1 | 3.61905 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 3.23585 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 2.78665 |
| PTK2 | protein tyrosine kinase 2 | 2.56 |
| COQ8A | coenzyme Q8A | 2.52645 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.5198 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 2.51928 |
| MTERF3 | mitochondrial transcription termination factor 3 | 2.50795 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 2.50165 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.4753 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 | 2.42585 |
| TESK1 | testis-specific kinase 1 | 2.36835 |
| RNF167 | ring finger protein 167 | 2.35065 |
| PIGB | phosphatidylinositol glycan anchor biosynthesis, class B | 2.29445 |
| TBC1D31 | TBC1 domain family, member 31 | 2.25935 |
| SMIM40 | small integral membrane protein 40 | 2.2083 |
| PREB | prolactin regulatory element binding | 2.16325 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.15815 |
| CYCS | cytochrome c, somatic | 2.08185 |
| SAP130 | Sin3A-associated protein, 130kDa | 2.074 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.0732 |
| H2BC21 | H2B clustered histone 21 | 2.0706 |
| HSPBAP1 | HSPB (heat shock 27kDa) associated protein 1 | 2.0538 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 2.0281 |
| LOC102724560 | cystathionine beta-synthase | 2.02385 |
| MSH2 | mutS homolog 2 | 2.0237 |
| SCRN1 | secernin 1 | 2.021 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 2.01295 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UBE3C | ubiquitin protein ligase E3C | -5.5133 |
| GOLT1B | golgi transport 1B | -5.3541 |
| FASTKD5 | FAST kinase domains 5 | -5.2188 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -5.18775 |
| MVP | major vault protein | -5.0913 |
| LDHD | lactate dehydrogenase D | -4.85965 |
| MRPS2 | mitochondrial ribosomal protein S2 | -4.8423 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.79265 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -4.75725 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.71785 |
| MAP7 | microtubule-associated protein 7 | -4.51758 |
| CCDC86 | coiled-coil domain containing 86 | -4.50385 |
| SLC35F2 | solute carrier family 35, member F2 | -3.84195 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.80845 |
| GNAS | GNAS complex locus | -3.44529 |
| HEATR1 | HEAT repeat containing 1 | -3.21932 |
| GLOD4 | glyoxalase domain containing 4 | -3.1628 |
| CCNB2 | cyclin B2 | -3.07175 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.8175 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.794 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.75205 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -2.74817 |
| GDF15 | growth differentiation factor 15 | -2.63575 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -2.5902 |
| PRPF4 | pre-mRNA processing factor 4 | -2.52283 |
| TAF5L | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa | -2.4141 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -2.3704 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -2.32363 |
| RBM34 | RNA binding motif protein 34 | -2.32057 |
| SCAMP2 | secretory carrier membrane protein 2 | -2.31525 |
| RWDD1 | RWD domain containing 1 | -2.2039 |
| FAH | fumarylacetoacetate hydrolase (fumarylacetoacetase) | -2.1631 |
| PEX26 | peroxisomal biogenesis factor 26 | -2.0765 |
| RNF4 | ring finger protein 4 | -2.0717 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 | -2.0521 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -2.0168 |
