| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | malathion 21.19 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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67 genes differentially expressed following the CRCGN011_HEPG2_24H:H13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 9.97065 |
| BZW2 | basic leucine zipper and W2 domains 2 | 5.8913 |
| TATDN2 | TatD DNase domain containing 2 | 5.45375 |
| CBR3 | carbonyl reductase 3 | 5.18395 |
| MOK | MOK protein kinase | 5.1029 |
| GSTZ1 | glutathione S-transferase zeta 1 | 5.0058 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.8548 |
| EPHA3 | EPH receptor A3 | 4.08463 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 3.68495 |
| EPHB2 | EPH receptor B2 | 3.6099 |
| MAP7 | microtubule-associated protein 7 | 3.54915 |
| LOC122526780 | uncharacterized LOC122526780 | 3.3921 |
| RXYLT1 | ribitol xylosyltransferase 1 | 3.21425 |
| UGDH | UDP-glucose 6-dehydrogenase | 3.0403 |
| NUP133 | nucleoporin 133kDa | 2.8804 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.80207 |
| MEST | mesoderm specific transcript | 2.7614 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 2.7182 |
| GPATCH8 | G patch domain containing 8 | 2.68568 |
| JADE2 | jade family PHD finger 2 | 2.62255 |
| CYB561 | cytochrome b561 | 2.49831 |
| TXNRD1 | thioredoxin reductase 1 | 2.4551 |
| EMC3 | ER membrane protein complex subunit 3 | 2.4027 |
| NFIL3 | nuclear factor, interleukin 3 regulated | 2.34855 |
| CYCS | cytochrome c, somatic | 2.3248 |
| COG4 | component of oligomeric golgi complex 4 | 2.2526 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 2.23115 |
| FAIM | Fas apoptotic inhibitory molecule | 2.22885 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | 2.10715 |
| TPD52L2 | tumor protein D52-like 2 | 2.0816 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.06159 |
| EBAG9 | estrogen receptor binding site associated, antigen, 9 | 2.05367 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 | 2.0485 |
| SRPRB | signal recognition particle receptor, B subunit | 2.02505 |
| SNX7 | sorting nexin 7 | 2.02185 |
| LOC102724560 | cystathionine beta-synthase | 2.0158 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -7.17805 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -6.68195 |
| KDM3A | lysine (K)-specific demethylase 3A | -5.33145 |
| TRIB3 | tribbles pseudokinase 3 | -5.14015 |
| LDHD | lactate dehydrogenase D | -5.0914 |
| GDF15 | growth differentiation factor 15 | -5.0 |
| MRPS2 | mitochondrial ribosomal protein S2 | -4.10195 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.4705 |
| GNAS | GNAS complex locus | -3.4368 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -3.1582 |
| PCNA | proliferating cell nuclear antigen | -3.1422 |
| TLCD3A | TLC domain containing 3A | -3.00375 |
| DCK | deoxycytidine kinase | -2.7476 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.66085 |
| HMX1 | H6 family homeobox 1 | -2.50035 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -2.28067 |
| IQCC | IQ motif containing C | -2.2684 |
| CYP11B2 | cytochrome P450, family 11, subfamily B, polypeptide 2 | -2.19725 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -2.19535 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | -2.15685 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.14832 |
| ADGRD2 | adhesion G protein-coupled receptor D2 | -2.1093 |
| NBAS | neuroblastoma amplified sequence | -2.10905 |
| GFUS | GDP-L-fucose synthase | -2.10605 |
| NEK7 | NIMA-related kinase 7 | -2.0745 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | -2.0556 |
| CNPY4 | canopy FGF signaling regulator 4 | -2.0444 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -2.0129 |
| CD82 | CD82 molecule | -2.0128 |
| FAM168B | family with sequence similarity 168, member B | -2.01005 |
| S100A4 | S100 calcium binding protein A4 | -2.00705 |
