| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | malathion 2.65 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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57 genes differentially expressed following the CRCGN011_HEPG2_24H:H16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CSK | c-src tyrosine kinase | 5.28395 |
| MOK | MOK protein kinase | 4.88375 |
| ABHD6 | abhydrolase domain containing 6 | 4.63502 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.53815 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 4.316 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 4.1501 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 4.01335 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.88945 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 3.37155 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.28945 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 3.2813 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.20902 |
| SMIM40 | small integral membrane protein 40 | 2.9931 |
| UBE2A | ubiquitin-conjugating enzyme E2A | 2.77387 |
| ZNF589 | zinc finger protein 589 | 2.76757 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 2.5333 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | 2.4422 |
| CLEC2D | C-type lectin domain family 2, member D | 2.4402 |
| IGFLR1 | IGF-like family receptor 1 | 2.4203 |
| SLC16A2 | solute carrier family 16, member 2 (thyroid hormone transporter) | 2.34715 |
| EPHA3 | EPH receptor A3 | 2.25782 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.22548 |
| CLEC10A | C-type lectin domain family 10, member A | 2.19515 |
| MAPK12 | mitogen-activated protein kinase 12 | 2.141 |
| HAX1 | HCLS1 associated protein X-1 | 2.13965 |
| CCNF | cyclin F | 2.11785 |
| IRF9 | interferon regulatory factor 9 | 2.09035 |
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 | 2.08795 |
| KLHL21 | kelch-like family member 21 | 2.0729 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -8.0021 |
| GNAS | GNAS complex locus | -7.12299 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -5.38605 |
| LDHD | lactate dehydrogenase D | -5.20785 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -5.0553 |
| SACM1L | SAC1 suppressor of actin mutations 1-like (yeast) | -4.8531 |
| CCDC86 | coiled-coil domain containing 86 | -4.8378 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.6109 |
| MAP7 | microtubule-associated protein 7 | -4.2355 |
| CCNB2 | cyclin B2 | -3.72265 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -3.45385 |
| ZW10 | zw10 kinetochore protein | -3.27765 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.23445 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -2.97664 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -2.96723 |
| PRPF4 | pre-mRNA processing factor 4 | -2.7022 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | -2.59965 |
| LRP5 | low density lipoprotein receptor-related protein 5 | -2.5485 |
| EXT1 | exostosin glycosyltransferase 1 | -2.5265 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.33617 |
| NCOA6 | nuclear receptor coactivator 6 | -2.3069 |
| UBE3C | ubiquitin protein ligase E3C | -2.2985 |
| SLC35F2 | solute carrier family 35, member F2 | -2.12685 |
| TRAP1 | TNF receptor-associated protein 1 | -2.12095 |
| KIF13B | kinesin family member 13B | -2.10665 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | -2.09665 |
| MTARC1 | mitochondrial amidoxime reducing component 1 | -2.05275 |
| RETREG1 | reticulophagy regulator 1 | -2.03425 |
