| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | malathion 0.66 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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49 genes differentially expressed following the CRCGN011_HEPG2_24H:H18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 4.787 |
| EAPP | E2F-associated phosphoprotein | 4.5936 |
| TLR4 | toll-like receptor 4 | 4.3818 |
| CHN1 | chimerin 1 | 4.33 |
| MAMLD1 | mastermind-like domain containing 1 | 4.14695 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 4.13995 |
| LCN2 | lipocalin 2 | 4.06615 |
| HDGFL3 | HDGF like 3 | 3.94392 |
| ABHD6 | abhydrolase domain containing 6 | 3.63733 |
| CYCS | cytochrome c, somatic | 3.38355 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.1206 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 2.9337 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 2.4646 |
| GPC1 | glypican 1 | 2.40447 |
| ARMC6 | armadillo repeat containing 6 | 2.33575 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 2.24015 |
| PRKCD | protein kinase C, delta | 2.2228 |
| PGM3 | phosphoglucomutase 3 | 2.17995 |
| COL11A1 | collagen, type XI, alpha 1 | 2.13132 |
| SCYL3 | SCY1-like 3 (S. cerevisiae) | 2.1275 |
| ZNF85 | zinc finger protein 85 | 2.1143 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 2.11005 |
| MAP9 | microtubule-associated protein 9 | 2.031 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -7.73625 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -5.325 |
| LDHD | lactate dehydrogenase D | -5.25395 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -5.0737 |
| GDF15 | growth differentiation factor 15 | -5.0 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.86735 |
| SLC35F2 | solute carrier family 35, member F2 | -3.95225 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.8188 |
| SPAG4 | sperm associated antigen 4 | -3.5163 |
| CDC25B | cell division cycle 25B | -3.5113 |
| NGRN | neugrin, neurite outgrowth associated | -3.48775 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -3.37315 |
| TLCD3A | TLC domain containing 3A | -3.14675 |
| RGS2 | regulator of G-protein signaling 2 | -2.9787 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.5111 |
| TGFB3 | transforming growth factor, beta 3 | -2.33015 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | -2.30365 |
| ANXA10 | annexin A10 | -2.2524 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit | -2.1287 |
| JMJD7 | jumonji domain containing 7 | -2.12205 |
| ACTL7A | actin-like 7A | -2.06075 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -2.05785 |
| ZNHIT1 | zinc finger, HIT-type containing 1 | -2.02715 |
| MTA1 | metastasis associated 1 | -2.01315 |
| IL10RA | interleukin 10 receptor, alpha | -2.0099 |
| NPDC1 | neural proliferation, differentiation and control, 1 | -2.0045 |