| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | triamcinolone 20.09 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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130 genes differentially expressed following the CRCGN011_HEPG2_24H:H19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 5.78885 |
| UBQLN2 | ubiquilin 2 | 5.13865 |
| TBPL1 | TBP-like 1 | 4.99055 |
| PNKP | polynucleotide kinase 3'-phosphatase | 4.8944 |
| TLR4 | toll-like receptor 4 | 4.82125 |
| STIMATE | STIM activating enhancer | 4.8009 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.6943 |
| NOTCH1 | notch 1 | 4.6691 |
| CSK | c-src tyrosine kinase | 4.66275 |
| IDE | insulin-degrading enzyme | 4.63063 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.6249 |
| ADRB2 | adrenoceptor beta 2, surface | 4.51355 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.47665 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 4.46695 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 4.441 |
| PRR15L | proline rich 15-like | 4.30655 |
| MELK | maternal embryonic leucine zipper kinase | 3.77395 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 3.7702 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.4982 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 3.36775 |
| WDR7 | WD repeat domain 7 | 3.3562 |
| EPN2 | epsin 2 | 3.16537 |
| CASC3 | cancer susceptibility candidate 3 | 2.99745 |
| DDIT4 | DNA-damage-inducible transcript 4 | 2.9947 |
| EXOSC4 | exosome component 4 | 2.94083 |
| CYCS | cytochrome c, somatic | 2.79495 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 2.74253 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | 2.6547 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 2.6143 |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 2.5601 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.52272 |
| DNMBP | dynamin binding protein | 2.475 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | 2.4704 |
| CHN1 | chimerin 1 | 2.45335 |
| ZNF589 | zinc finger protein 589 | 2.4259 |
| PUF60 | poly-U binding splicing factor 60KDa | 2.4063 |
| NOSIP | nitric oxide synthase interacting protein | 2.39595 |
| IL1R2 | interleukin 1 receptor, type II | 2.39547 |
| CTSL | cathepsin L | 2.3888 |
| CDC45 | cell division cycle 45 | 2.38595 |
| ARL4A | ADP-ribosylation factor-like 4A | 2.38545 |
| BIRC2 | baculoviral IAP repeat containing 2 | 2.37265 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | 2.36735 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 | 2.3423 |
| CHEK2 | checkpoint kinase 2 | 2.28542 |
| LAMB3 | laminin, beta 3 | 2.27825 |
| ZFP36 | ZFP36 ring finger protein | 2.25355 |
| ALCAM | activated leukocyte cell adhesion molecule | 2.21705 |
| RIPOR1 | RHO family interacting cell polarization regulator 1 | 2.20645 |
| STC1 | stanniocalcin 1 | 2.19045 |
| EMC9 | ER membrane protein complex subunit 9 | 2.16295 |
| TUBGCP4 | tubulin, gamma complex associated protein 4 | 2.15455 |
| EPHA3 | EPH receptor A3 | 2.13838 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | 2.1244 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.12405 |
| JADE2 | jade family PHD finger 2 | 2.12273 |
| GATA2 | GATA binding protein 2 | 2.11037 |
| CENPM | centromere protein M | 2.10915 |
| DUSP6 | dual specificity phosphatase 6 | 2.10735 |
| VASP | vasodilator-stimulated phosphoprotein | 2.0707 |
| PIH1D1 | PIH1 domain containing 1 | 2.0637 |
| SOX17 | SRY (sex determining region Y)-box 17 | 2.0525 |
| KIF4A | kinesin family member 4A | 2.0414 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -10.0 |
| PCNA | proliferating cell nuclear antigen | -8.42015 |
| GNAS | GNAS complex locus | -7.36774 |
| B4GAT1 | beta-1,4-glucuronyltransferase 1 | -5.7408 |
| LDHD | lactate dehydrogenase D | -5.46525 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.3981 |
| PEG10 | paternally expressed 10 | -5.0 |
| NUP85 | nucleoporin 85kDa | -4.86305 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -4.7314 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -4.46055 |
| YME1L1 | YME1-like 1 ATPase | -4.33445 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -4.24725 |
| GDF15 | growth differentiation factor 15 | -4.17225 |
| KCTD2 | potassium channel tetramerization domain containing 2 | -4.06295 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.02165 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.9211 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.62435 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.53385 |
| TLCD3A | TLC domain containing 3A | -3.1363 |
| WASHC4 | WASH complex subunit 4 | -2.90388 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -2.90009 |
| MSMO1 | methylsterol monooxygenase 1 | -2.8676 |
| GABRG2 | gamma-aminobutyric acid (GABA) A receptor, gamma 2 | -2.6894 |
| JPT1 | Jupiter microtubule associated homolog 1 | -2.66355 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -2.58753 |
| ATP5F1C | ATP synthase F1 subunit gamma | -2.57723 |
| EVPL | envoplakin | -2.55745 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.52443 |
| CRH | corticotropin releasing hormone | -2.45692 |
| WDR37 | WD repeat domain 37 | -2.4493 |
| CHIT1 | chitinase 1 (chitotriosidase) | -2.42035 |
| CDH18 | cadherin 18, type 2 | -2.4178 |
| DSG2 | desmoglein 2 | -2.4095 |
| CASP8AP2 | caspase 8 associated protein 2 | -2.3977 |
| MRPL58 | mitochondrial ribosomal protein L58 | -2.38575 |
| DPF3 | D4, zinc and double PHD fingers, family 3 | -2.3855 |
| FDXR | ferredoxin reductase | -2.37035 |
| GABRA6 | gamma-aminobutyric acid (GABA) A receptor, alpha 6 | -2.2834 |
| KIAA1614 | KIAA1614 | -2.26785 |
| PANK2 | pantothenate kinase 2 | -2.25735 |
| NAT9 | N-acetyltransferase 9 (GCN5-related, putative) | -2.23895 |
| RNF167 | ring finger protein 167 | -2.23505 |
| MRPS7 | mitochondrial ribosomal protein S7 | -2.2345 |
| GABRA1 | gamma-aminobutyric acid (GABA) A receptor, alpha 1 | -2.22675 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -2.21813 |
| HBZ | hemoglobin, zeta | -2.2134 |
| TMEM230 | transmembrane protein 230 | -2.2038 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.17578 |
| CHEK1 | checkpoint kinase 1 | -2.16733 |
| PCDHB6 | protocadherin beta 6 | -2.1655 |
| PFDN1 | prefoldin subunit 1 | -2.15565 |
| CRNKL1 | crooked neck pre-mRNA splicing factor 1 | -2.1456 |
| VDAC1 | voltage-dependent anion channel 1 | -2.14418 |
| USP22 | ubiquitin specific peptidase 22 | -2.14108 |
| GGA3 | golgi-associated, gamma adaptin ear containing, ARF binding protein 3 | -2.13538 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | -2.1259 |
| SLC1A6 | solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 | -2.10265 |
| HOPX | HOP homeobox | -2.09025 |
| HLTF | helicase-like transcription factor | -2.0825 |
| CRBN | cereblon | -2.07825 |
| CYTL1 | cytokine-like 1 | -2.073 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 | -2.0613 |
| MMP24-AS1-EDEM2 | MMP24-AS1-EDEM2 readthrough | -2.04775 |
| PCDHB3 | protocadherin beta 3 | -2.0447 |
| SUMO4 | small ubiquitin-like modifier 4 | -2.0247 |
| CDK20 | cyclin-dependent kinase 20 | -2.0067 |
| SNRPB2 | small nuclear ribonucleoprotein polypeptide B | -2.0035 |
