| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | triamcinolone 5.02 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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108 genes differentially expressed following the CRCGN011_HEPG2_24H:H21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PRR15L | proline rich 15-like | 6.17955 |
| CCNF | cyclin F | 5.04958 |
| MYLK | myosin light chain kinase | 4.92965 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 4.78342 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.75285 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.58025 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.40175 |
| STK10 | serine/threonine kinase 10 | 4.30457 |
| LCN2 | lipocalin 2 | 4.30255 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.29975 |
| KDM5A | lysine (K)-specific demethylase 5A | 4.1907 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.95805 |
| SSBP2 | single-stranded DNA binding protein 2 | 3.67135 |
| BAX | BCL2-associated X protein | 3.45177 |
| TLR4 | toll-like receptor 4 | 3.1733 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 3.08135 |
| ATP11B | ATPase, class VI, type 11B | 2.97715 |
| DDIT4 | DNA-damage-inducible transcript 4 | 2.8498 |
| IFI6 | interferon, alpha-inducible protein 6 | 2.74725 |
| EXOSC4 | exosome component 4 | 2.74723 |
| FZD7 | frizzled class receptor 7 | 2.72272 |
| PLSCR3 | phospholipid scramblase 3 | 2.6382 |
| LOC128966570 | alpha-amylase 1B | 2.62925 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | 2.57025 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.53925 |
| LPIN2 | lipin 2 | 2.49275 |
| ATF6 | activating transcription factor 6 | 2.48803 |
| FASTKD5 | FAST kinase domains 5 | 2.48635 |
| CD302 | CD302 molecule | 2.46475 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 2.45725 |
| NUTF2 | nuclear transport factor 2 | 2.38625 |
| TIPRL | TOR signaling pathway regulator | 2.3806 |
| NINJ2 | ninjurin 2 | 2.36605 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | 2.3652 |
| STRN3 | striatin, calmodulin binding protein 3 | 2.32135 |
| NIBAN1 | niban apoptosis regulator 1 | 2.31155 |
| TBCCD1 | TBCC domain containing 1 | 2.30715 |
| PKN1 | protein kinase N1 | 2.2922 |
| CARD8 | caspase recruitment domain family, member 8 | 2.2426 |
| WDR76 | WD repeat domain 76 | 2.2391 |
| KIFBP | kinesin family binding protein | 2.2301 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | 2.20915 |
| SENP2 | SUMO1/sentrin/SMT3 specific peptidase 2 | 2.20055 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.17815 |
| ACOT8 | acyl-CoA thioesterase 8 | 2.1352 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 2.1064 |
| ZNF652 | zinc finger protein 652 | 2.0943 |
| IFI44L | interferon-induced protein 44-like | 2.0874 |
| GAS2 | growth arrest-specific 2 | 2.07245 |
| ATAD2 | ATPase family, AAA domain containing 2 | 2.07165 |
| EVL | Enah/Vasp-like | 2.0636 |
| MAGT1 | magnesium transporter 1 | 2.0562 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 2.03875 |
| GOLGA7 | golgin A7 | 2.0336 |
| PTGES | prostaglandin E synthase | 2.01568 |
| FAM8A1 | family with sequence similarity 8, member A1 | 2.01535 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 2.01205 |
| JRKL | JRK-like | 2.00625 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD320 | CD320 molecule | -5.6839 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -5.4078 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -5.16605 |
| VAT1 | vesicle amine transport 1 | -5.0 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -5.0 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.7725 |
| CCNB2 | cyclin B2 | -4.75045 |
| LDHD | lactate dehydrogenase D | -4.6751 |
| CDC20 | cell division cycle 20 | -4.66275 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -4.41785 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -4.33325 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.2996 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -4.24385 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.6919 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.3701 |
| ADI1 | acireductone dioxygenase 1 | -3.25315 |
| PCNA | proliferating cell nuclear antigen | -3.2125 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | -3.2036 |
| YME1L1 | YME1-like 1 ATPase | -3.19122 |
| CAB39 | calcium binding protein 39 | -2.87075 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 | -2.6615 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.5257 |
| TRMT61B | tRNA methyltransferase 61B | -2.46295 |
| RGCC | regulator of cell cycle | -2.46125 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.43155 |
| HS6ST1 | heparan sulfate 6-O-sulfotransferase 1 | -2.416 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -2.3364 |
| ACLY | ATP citrate lyase | -2.3343 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -2.3082 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -2.30425 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 | -2.29805 |
| TP53RK | TP53 regulating kinase | -2.243 |
| AQP8 | aquaporin 8 | -2.24005 |
| LINC02854 | long intergenic non-protein coding RNA 2854 | -2.2343 |
| TRIM36 | tripartite motif containing 36 | -2.16665 |
| GUCA2B | guanylate cyclase activator 2B (uroguanylin) | -2.15985 |
| CRMP1 | collapsin response mediator protein 1 | -2.1544 |
| GRB2 | growth factor receptor-bound protein 2 | -2.1342 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 | -2.13295 |
| ACTR1B | ARP1 actin-related protein 1 homolog B, centractin beta (yeast) | -2.11705 |
| ECSIT | ECSIT signalling integrator | -2.11365 |
| MOB3B | MOB kinase activator 3B | -2.1111 |
| RGS2 | regulator of G-protein signaling 2 | -2.08925 |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) | -2.0846 |
| TBC1D12 | TBC1 domain family, member 12 | -2.0834 |
| CLEC10A | C-type lectin domain family 10, member A | -2.0693 |
| GBA3 | glucosidase, beta, acid 3 (gene/pseudogene) | -2.06285 |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 | -2.03605 |
| CD177 | CD177 molecule | -2.025 |
| DRC4 | dynein regulatory complex subunit 4 | -2.00355 |
