| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | triamcinolone 1.26 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
137 genes differentially expressed following the CRCGN011_HEPG2_24H:H23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CCL2 | chemokine (C-C motif) ligand 2 | 7.8901 |
| MYLK | myosin light chain kinase | 5.3732 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 5.26375 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 5.0459 |
| STIMATE | STIM activating enhancer | 4.82515 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 4.80393 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 4.7225 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 4.71513 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 4.11918 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 3.92455 |
| MAP7 | microtubule-associated protein 7 | 3.752 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.68225 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 3.66095 |
| AMDHD2 | amidohydrolase domain containing 2 | 3.5663 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 3.5584 |
| SSBP2 | single-stranded DNA binding protein 2 | 3.26857 |
| HSPA1A | heat shock 70kDa protein 1A | 3.258 |
| DENND2D | DENN/MADD domain containing 2D | 3.18445 |
| PLSCR3 | phospholipid scramblase 3 | 2.98525 |
| CHEK2 | checkpoint kinase 2 | 2.88535 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 2.88328 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 2.84265 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 2.81225 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | 2.7647 |
| JADE2 | jade family PHD finger 2 | 2.606 |
| FZD7 | frizzled class receptor 7 | 2.60355 |
| KCTD14 | potassium channel tetramerization domain containing 14 | 2.5522 |
| FPGS | folylpolyglutamate synthase | 2.52915 |
| GTPBP8 | GTP-binding protein 8 (putative) | 2.4783 |
| TOM1L1 | target of myb1 (chicken)-like 1 | 2.4759 |
| SMIM40 | small integral membrane protein 40 | 2.46235 |
| KLHL9 | kelch-like family member 9 | 2.44597 |
| TSPAN4 | tetraspanin 4 | 2.37613 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.3671 |
| ILK | integrin-linked kinase | 2.3483 |
| FPGT | fucose-1-phosphate guanylyltransferase | 2.33415 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.3163 |
| LCN2 | lipocalin 2 | 2.31385 |
| IMPACT | impact RWD domain protein | 2.2937 |
| STK10 | serine/threonine kinase 10 | 2.2778 |
| PKN1 | protein kinase N1 | 2.27538 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 2.2547 |
| GPATCH8 | G patch domain containing 8 | 2.25445 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | 2.20285 |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) | 2.1856 |
| HIP1 | huntingtin interacting protein 1 | 2.1719 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 2.1656 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 | 2.1549 |
| GK | glycerol kinase | 2.15363 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 2.1501 |
| BRIX1 | BRX1, biogenesis of ribosomes | 2.1433 |
| TMEM9B | TMEM9 domain family, member B | 2.12865 |
| TNFSF12-TNFSF13 | TNFSF12-TNFSF13 readthrough | 2.11483 |
| HDAC2 | histone deacetylase 2 | 2.11455 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | 2.09905 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | 2.0808 |
| COG4 | component of oligomeric golgi complex 4 | 2.0804 |
| FERMT1 | fermitin family member 1 | 2.07265 |
| PIH1D1 | PIH1 domain containing 1 | 2.06035 |
| DDIT4 | DNA-damage-inducible transcript 4 | 2.0586 |
| GALE | UDP-galactose-4-epimerase | 2.03405 |
| RNASE4 | ribonuclease, RNase A family, 4 | 2.03338 |
| PIGT | phosphatidylinositol glycan anchor biosynthesis, class T | 2.02585 |
| HSPB1 | heat shock 27kDa protein 1 | 2.02565 |
| ATP5MC1 | ATP synthase membrane subunit c locus 1 | 2.0211 |
| C1S | complement component 1, s subcomponent | 2.0192 |
| C1GALT1C1 | C1GALT1-specific chaperone 1 | 2.0056 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 2.00335 |
| PDGFRL | platelet-derived growth factor receptor-like | 2.00255 |
| TBCB | tubulin folding cofactor B | 2.00173 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GNAS | GNAS complex locus | -7.32423 |
| TP53BP2 | tumor protein p53 binding protein 2 | -5.74425 |
| VAT1 | vesicle amine transport 1 | -5.11335 |
| DNM1L | dynamin 1-like | -5.10155 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -5.0886 |
| GDF15 | growth differentiation factor 15 | -5.0 |
| CD320 | CD320 molecule | -4.8516 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.749 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -4.69525 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -4.65525 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.65065 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.65 |
| FGFR4 | fibroblast growth factor receptor 4 | -4.6386 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.55135 |
| NGRN | neugrin, neurite outgrowth associated | -4.2717 |
| EIF5 | eukaryotic translation initiation factor 5 | -4.19379 |
| ADI1 | acireductone dioxygenase 1 | -4.05755 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -3.80685 |
| CDC20 | cell division cycle 20 | -3.54395 |
| HMG20B | high mobility group 20B | -3.34738 |
| CCNB2 | cyclin B2 | -3.26535 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.1494 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -3.0605 |
| CAPN15 | calpain 15 | -3.0089 |
| TBC1D31 | TBC1 domain family, member 31 | -2.87515 |
| GUK1 | guanylate kinase 1 | -2.8611 |
| RBM15B | RNA binding motif protein 15B | -2.85455 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.79605 |
| CCDC51 | coiled-coil domain containing 51 | -2.7051 |
| SERHL2 | serine hydrolase-like 2 | -2.63523 |
| PGM1 | phosphoglucomutase 1 | -2.59645 |
| RASL10A | RAS-like, family 10, member A | -2.55165 |
| TCERG1 | transcription elongation regulator 1 | -2.5326 |
| RPAP1 | RNA polymerase II associated protein 1 | -2.50475 |
| PRPF4 | pre-mRNA processing factor 4 | -2.49668 |
| ST18 | suppression of tumorigenicity 18, zinc finger | -2.48515 |
| LDHB | lactate dehydrogenase B | -2.4665 |
| AGER | advanced glycosylation end product-specific receptor | -2.39313 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.39307 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -2.30935 |
| GABRG2 | gamma-aminobutyric acid (GABA) A receptor, gamma 2 | -2.2996 |
| BCHE | butyrylcholinesterase | -2.2786 |
| RTN4 | reticulon 4 | -2.21993 |
| LSAMP | limbic system-associated membrane protein | -2.20165 |
| ICAM4 | intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) | -2.19835 |
| KBTBD2 | kelch repeat and BTB (POZ) domain containing 2 | -2.1922 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -2.172 |
| INSIG1 | insulin induced gene 1 | -2.16895 |
| EIF3D | eukaryotic translation initiation factor 3, subunit D | -2.13815 |
| LUC7L | LUC7-like (S. cerevisiae) | -2.13295 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -2.12255 |
| DENND3 | DENN/MADD domain containing 3 | -2.11768 |
| NPY | neuropeptide Y | -2.11025 |
| PARP6 | poly (ADP-ribose) polymerase family, member 6 | -2.1008 |
| ERGIC2 | ERGIC and golgi 2 | -2.09465 |
| PCDH17 | protocadherin 17 | -2.0927 |
| YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial | -2.0676 |
| VILL | villin-like | -2.0501 |
| NDST3 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 | -2.0472 |
| LHX6 | LIM homeobox 6 | -2.0439 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -2.04115 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -2.03653 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV | -2.0365 |
| NONO | non-POU domain containing, octamer-binding | -2.0324 |
| POLR3E | polymerase (RNA) III (DNA directed) polypeptide E (80kD) | -2.01445 |
| CCNC | cyclin C | -2.01295 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | -2.00515 |
