CRCGN011_HEPG2_24H:I06 Gene Set
Genes
47 genes differentially expressed following the CRCGN011_HEPG2_24H:I06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
5.26947
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
5.1833
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.87875
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.8466
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
4.4637
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
4.26018
|
|
KIF5C
|
kinesin family member 5C
|
4.0296
|
|
MEST
|
mesoderm specific transcript
|
3.82835
|
|
PFKL
|
phosphofructokinase, liver
|
3.6369
|
|
CYCS
|
cytochrome c, somatic
|
3.62145
|
|
ADO
|
2-aminoethanethiol (cysteamine) dioxygenase
|
3.2292
|
|
ZNF589
|
zinc finger protein 589
|
3.18807
|
|
ADAT1
|
adenosine deaminase, tRNA-specific 1
|
3.1479
|
|
DDX10
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
|
3.14025
|
|
EPN2
|
epsin 2
|
2.97785
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
2.94805
|
|
KLHL21
|
kelch-like family member 21
|
2.9218
|
|
LCN2
|
lipocalin 2
|
2.87065
|
|
CHN1
|
chimerin 1
|
2.52815
|
|
HPRT1
|
hypoxanthine phosphoribosyltransferase 1
|
2.3708
|
|
ZBTB35
|
zinc finger and BTB domain containing 35
|
2.26305
|
|
MPC2
|
mitochondrial pyruvate carrier 2
|
2.21585
|
|
VIM
|
vimentin
|
2.1487
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
2.1101
|
|
BSG
|
basigin (Ok blood group)
|
2.0305
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
GDF15
|
growth differentiation factor 15
|
-5.9313
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-4.8549
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-4.79515
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-4.4657
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.72528
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.6467
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.5183
|
|
DNTTIP2
|
deoxynucleotidyltransferase, terminal, interacting protein 2
|
-3.2475
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.03255
|
|
CEMIP2
|
cell migration inducing hyaluronidase 2
|
-2.9386
|
|
CHIC2
|
cysteine-rich hydrophobic domain 2
|
-2.879
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-2.86488
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.70497
|
|
DDB2
|
damage-specific DNA binding protein 2, 48kDa
|
-2.30305
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.28635
|
|
MAP3K8
|
mitogen-activated protein kinase kinase kinase 8
|
-2.25145
|
|
PSG2
|
pregnancy specific beta-1-glycoprotein 2
|
-2.1649
|
|
RANBP6
|
RAN binding protein 6
|
-2.121
|
|
TM2D1
|
TM2 domain containing 1
|
-2.11585
|
|
EVA1B
|
eva-1 homolog B (C. elegans)
|
-2.0917
|
|
ZNF318
|
zinc finger protein 318
|
-2.0147
|
|
MED28
|
mediator complex subunit 28
|
-2.0074
|
