| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | ITE 5.24 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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140 genes differentially expressed following the CRCGN011_HEPG2_24H:I09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 7.63285 |
| NMU | neuromedin U | 5.6638 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 5.6288 |
| UBQLN2 | ubiquilin 2 | 5.5599 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 5.12665 |
| CSK | c-src tyrosine kinase | 5.08485 |
| PPARG | peroxisome proliferator-activated receptor gamma | 5.08055 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.99125 |
| PLS1 | plastin 1 | 4.3914 |
| CNPY3 | canopy FGF signaling regulator 3 | 4.26655 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 4.24455 |
| FZD1 | frizzled class receptor 1 | 4.06227 |
| MEST | mesoderm specific transcript | 3.9714 |
| MAP7 | microtubule-associated protein 7 | 3.85808 |
| AMDHD2 | amidohydrolase domain containing 2 | 3.52205 |
| FZD7 | frizzled class receptor 7 | 3.06107 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | 3.02985 |
| TEX10 | testis expressed 10 | 2.6563 |
| SQOR | sulfide quinone oxidoreductase | 2.63335 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 2.5383 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 2.4948 |
| PRICKLE3 | prickle homolog 3 (Drosophila) | 2.486 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 2.4799 |
| DHX32 | DEAH (Asp-Glu-Ala-His) box polypeptide 32 | 2.4711 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 2.39825 |
| ICOS | inducible T-cell co-stimulator | 2.38135 |
| SORBS3 | sorbin and SH3 domain containing 3 | 2.36333 |
| ACVR2A | activin A receptor, type IIA | 2.36075 |
| WNT8B | wingless-type MMTV integration site family, member 8B | 2.351 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 | 2.35065 |
| PRRX1 | paired related homeobox 1 | 2.33645 |
| LOC122526780 | uncharacterized LOC122526780 | 2.3338 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | 2.32895 |
| PSMA4 | proteasome (prosome, macropain) subunit, alpha type, 4 | 2.3 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.28907 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 | 2.28755 |
| MVP | major vault protein | 2.2634 |
| CD1B | CD1b molecule | 2.2608 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | 2.2572 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | 2.25572 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 2.24342 |
| LAP3 | leucine aminopeptidase 3 | 2.23255 |
| RGCC | regulator of cell cycle | 2.23165 |
| FGF5 | fibroblast growth factor 5 | 2.22985 |
| PTK2 | protein tyrosine kinase 2 | 2.22003 |
| LRRC61 | leucine rich repeat containing 61 | 2.2088 |
| KAT6A | K(lysine) acetyltransferase 6A | 2.20397 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.19465 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 2.18415 |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 | 2.1743 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | 2.16295 |
| VAT1 | vesicle amine transport 1 | 2.15885 |
| ZFP69B | ZFP69 zinc finger protein B | 2.15345 |
| IL6 | interleukin 6 | 2.14455 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 2.1439 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) | 2.12045 |
| RBM15B | RNA binding motif protein 15B | 2.1198 |
| CORO1A | coronin, actin binding protein, 1A | 2.11345 |
| CTLA4 | cytotoxic T-lymphocyte-associated protein 4 | 2.0893 |
| H2BC21 | H2B clustered histone 21 | 2.0834 |
| VN1R1 | vomeronasal 1 receptor 1 | 2.07885 |
| EDN1 | endothelin 1 | 2.073 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 | 2.06823 |
| FAAP24 | FA core complex associated protein 24 | 2.06625 |
| SH2D1A | SH2 domain containing 1A | 2.05994 |
| VAX2 | ventral anterior homeobox 2 | 2.05575 |
| EED | embryonic ectoderm development | 2.05323 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | 2.05155 |
| TOPBP1 | topoisomerase (DNA) II binding protein 1 | 2.05105 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | 2.04362 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit | 2.0325 |
| USB1 | U6 snRNA biogenesis 1 | 2.03185 |
| ERVMER34-1 | endogenous retrovirus group MER34, member 1 | 2.0216 |
| RAB21 | RAB21, member RAS oncogene family | 2.0199 |
| FGF20 | fibroblast growth factor 20 | 2.0155 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MRPS2 | mitochondrial ribosomal protein S2 | -8.6377 |
| HMG20B | high mobility group 20B | -6.60978 |
| SLC35F2 | solute carrier family 35, member F2 | -6.31625 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -5.21155 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -4.9598 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.84695 |
| LDHD | lactate dehydrogenase D | -4.81815 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -4.66275 |
| TCTN1 | tectonic family member 1 | -3.67845 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -3.54932 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.459 |
| GLOD4 | glyoxalase domain containing 4 | -3.40475 |
| PMPCA | peptidase (mitochondrial processing) alpha | -3.3592 |
| LYPLA1 | lysophospholipase I | -3.35722 |
| YME1L1 | YME1-like 1 ATPase | -3.29443 |
| KIF14 | kinesin family member 14 | -3.28685 |
| WASHC4 | WASH complex subunit 4 | -3.18197 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | -3.13015 |
| NELFB | negative elongation factor complex member B | -3.0236 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.99905 |
| HMGA2 | high mobility group AT-hook 2 | -2.89765 |
| PAEP | progestagen-associated endometrial protein | -2.76765 |
| SOAT2 | sterol O-acyltransferase 2 | -2.73892 |
| HEATR1 | HEAT repeat containing 1 | -2.7181 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.6722 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.62645 |
| FBXO7 | F-box protein 7 | -2.5332 |
| RPS5 | ribosomal protein S5 | -2.5242 |
| SNX11 | sorting nexin 11 | -2.5192 |
| MRPL49 | mitochondrial ribosomal protein L49 | -2.51195 |
| THOP1 | thimet oligopeptidase 1 | -2.5042 |
| FHL2 | four and a half LIM domains 2 | -2.49385 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -2.41165 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -2.36985 |
| PLOD3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | -2.3577 |
| SSNA1 | Sjogren syndrome nuclear autoantigen 1 | -2.3555 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | -2.32708 |
| PROS1 | protein S (alpha) | -2.2694 |
| AHCYL1 | adenosylhomocysteinase-like 1 | -2.26675 |
| GRN | granulin | -2.25187 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.2501 |
| MMS19 | MMS19 nucleotide excision repair homolog (S. cerevisiae) | -2.22675 |
| GAA | glucosidase, alpha; acid | -2.22195 |
| TSC22D4 | TSC22 domain family, member 4 | -2.21175 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -2.20935 |
| MECR | mitochondrial trans-2-enoyl-CoA reductase | -2.19355 |
| MVD | mevalonate (diphospho) decarboxylase | -2.18705 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -2.18695 |
| SKIC2 | SKI2 subunit of superkiller complex | -2.1859 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -2.18523 |
| PTBP1 | polypyrimidine tract binding protein 1 | -2.1623 |
| HAX1 | HCLS1 associated protein X-1 | -2.157 |
| FAT1 | FAT atypical cadherin 1 | -2.15675 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | -2.14165 |
| FAAP100 | FA core complex associated protein 100 | -2.1378 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa | -2.10415 |
| NDUFS7 | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) | -2.097 |
| RGS2 | regulator of G-protein signaling 2 | -2.0961 |
| PPP1R26 | protein phosphatase 1, regulatory subunit 26 | -2.0947 |
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 | -2.0862 |
| BST2 | bone marrow stromal cell antigen 2 | -2.07695 |
| SUCO | SUN domain containing ossification factor | -2.075 |
| IER2 | immediate early response 2 | -2.05735 |
| SMIM44 | small integral membrane protein 44 | -2.03128 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | -2.02565 |
