CRCGN011_HEPG2_24H:I18 Gene Set
Genes
50 genes differentially expressed following the CRCGN011_HEPG2_24H:I18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CYCS
|
cytochrome c, somatic
|
6.0215
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
5.77475
|
|
CSK
|
c-src tyrosine kinase
|
5.48555
|
|
NMU
|
neuromedin U
|
5.31445
|
|
PRR15L
|
proline rich 15-like
|
5.2162
|
|
LCN2
|
lipocalin 2
|
5.0
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.9959
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.80155
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
4.10472
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
3.55433
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
3.39935
|
|
PRKCH
|
protein kinase C, eta
|
2.83068
|
|
RNF167
|
ring finger protein 167
|
2.75805
|
|
MELK
|
maternal embryonic leucine zipper kinase
|
2.733
|
|
GPATCH8
|
G patch domain containing 8
|
2.7096
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.45025
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.405
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
2.34335
|
|
KLHL9
|
kelch-like family member 9
|
2.25055
|
|
E2F5
|
E2F transcription factor 5, p130-binding
|
2.19705
|
|
TAB2
|
TGF-beta activated kinase 1/MAP3K7 binding protein 2
|
2.19688
|
|
TNFSF4
|
tumor necrosis factor (ligand) superfamily, member 4
|
2.18915
|
|
CRABP1
|
cellular retinoic acid binding protein 1
|
2.0447
|
|
TUBD1
|
tubulin, delta 1
|
2.0302
|
|
ZNF711
|
zinc finger protein 711
|
2.0071
|
|
SPCS1
|
signal peptidase complex subunit 1 homolog (S. cerevisiae)
|
2.0055
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-10.0
|
|
ZNF586
|
zinc finger protein 586
|
-6.69985
|
|
SCAND1
|
SCAN domain containing 1
|
-5.6039
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.90575
|
|
CCNB2
|
cyclin B2
|
-4.27255
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.6229
|
|
GDF15
|
growth differentiation factor 15
|
-3.45965
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-3.33405
|
|
RPS5
|
ribosomal protein S5
|
-3.32585
|
|
ZNF134
|
zinc finger protein 134
|
-3.3175
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-3.1036
|
|
USP22
|
ubiquitin specific peptidase 22
|
-2.4761
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
-2.39379
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.3812
|
|
POP7
|
processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
|
-2.381
|
|
ZNF211
|
zinc finger protein 211
|
-2.2861
|
|
ZNF551
|
zinc finger protein 551
|
-2.22755
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
-2.2073
|
|
TNFRSF25
|
tumor necrosis factor receptor superfamily, member 25
|
-2.19832
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.1962
|
|
LGR4
|
leucine-rich repeat containing G protein-coupled receptor 4
|
-2.13645
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-2.1215
|
|
DOK2
|
docking protein 2, 56kDa
|
-2.0351
|
|
PLPP1
|
phospholipid phosphatase 1
|
-2.02815
|
