CRCGN011_HEPG2_24H:I20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description sulforaphane 9.98 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

450 genes differentially expressed following the CRCGN011_HEPG2_24H:I20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TXNRD1 thioredoxin reductase 1 7.71705
LCN2 lipocalin 2 6.3338
ABHD4 abhydrolase domain containing 4 6.22235
KEAP1 kelch-like ECH-associated protein 1 5.47355
BZW2 basic leucine zipper and W2 domains 2 5.1467
CIAO3 cytosolic iron-sulfur assembly component 3 5.05165
LRP10 low density lipoprotein receptor-related protein 10 5.01565
EGR1 early growth response 1 4.9895
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 4.95915
CHMP6 charged multivesicular body protein 6 4.86185
UBQLN2 ubiquilin 2 4.75945
TLR4 toll-like receptor 4 4.5731
E2F2 E2F transcription factor 2 4.5396
SQSTM1 sequestosome 1 4.52745
HOXA10 homeobox A10 4.4381
INPP1 inositol polyphosphate-1-phosphatase 4.4266
PLS1 plastin 1 4.3638
UGDH UDP-glucose 6-dehydrogenase 4.2958
STIMATE STIM activating enhancer 4.1835
FOSL1 FOS-like antigen 1 4.14155
CNPY3 canopy FGF signaling regulator 3 4.0275
GPER1 G protein-coupled estrogen receptor 1 4.0154
RXYLT1 ribitol xylosyltransferase 1 3.86865
EPHB2 EPH receptor B2 3.86445
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 3.82835
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 3.7901
STK10 serine/threonine kinase 10 3.63818
SNAP25 synaptosomal-associated protein, 25kDa 3.63777
GCLM glutamate-cysteine ligase, modifier subunit 3.534
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 3.48895
TBPL1 TBP-like 1 3.27395
PADI4 peptidyl arginine deiminase, type IV 3.238
NEUROD2 neuronal differentiation 2 3.2244
WNT10B wingless-type MMTV integration site family, member 10B 3.20235
SQOR sulfide quinone oxidoreductase 3.12125
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 3.07775
GSR glutathione reductase 3.0699
HOXA11 homeobox A11 3.04575
TRIB1 tribbles pseudokinase 1 3.0186
GLRX glutaredoxin (thioltransferase) 2.99905
RAB21 RAB21, member RAS oncogene family 2.98675
TET3 tet methylcytosine dioxygenase 3 2.97305
MYC v-myc avian myelocytomatosis viral oncogene homolog 2.927
TBXA2R thromboxane A2 receptor 2.91179
PROP1 PROP paired-like homeobox 1 2.90595
RBKS ribokinase 2.9007
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5 2.88975
CLDN11 claudin 11 2.87805
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 2.8316
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 2.8143
VNN2 vanin 2 2.8091
MRPS18C mitochondrial ribosomal protein S18C 2.80165
IER3 immediate early response 3 2.7913
DYNLT3 dynein, light chain, Tctex-type 3 2.7792
FOXD2 forkhead box D2 2.77735
BIRC2 baculoviral IAP repeat containing 2 2.7753
RUSC2 RUN and SH3 domain containing 2 2.7644
SLC35F2 solute carrier family 35, member F2 2.7552
TBP TATA box binding protein 2.7528
TRIM25 tripartite motif containing 25 2.7519
SDF2 stromal cell-derived factor 2 2.7347
NAXE NAD(P)HX epimerase 2.7282
SNAI1 snail family zinc finger 1 2.7276
NR0B1 nuclear receptor subfamily 0, group B, member 1 2.71027
TIMP2 TIMP metallopeptidase inhibitor 2 2.6943
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 2.6914
SART1 squamous cell carcinoma antigen recognized by T cells 2.6847
UNC13D unc-13 homolog D (C. elegans) 2.68345
PAMR1 peptidase domain containing associated with muscle regeneration 1 2.6823
GBE1 glucan (1,4-alpha-), branching enzyme 1 2.6771
OR1D2 olfactory receptor, family 1, subfamily D, member 2 2.6708
CRYGC crystallin, gamma C 2.66845
KCTD20 potassium channel tetramerization domain containing 20 2.66675
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 2.65975
CRYGA crystallin, gamma A 2.6591
CEP170 centrosomal protein 170kDa 2.63862
FCAR Fc fragment of IgA receptor 2.63
CCNF cyclin F 2.6278
NRL neural retina leucine zipper 2.62485
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10 2.6239
SIRPB1 signal-regulatory protein beta 1 2.6068
BAD BCL2-associated agonist of cell death 2.5942
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 2.592
DUSP2 dual specificity phosphatase 2 2.59115
GPR25 G protein-coupled receptor 25 2.58735
SCIN scinderin 2.5722
STRA6 stimulated by retinoic acid 6 2.56435
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 2.5534
NINJ1 ninjurin 1 2.5519
CD248 CD248 molecule, endosialin 2.5513
HOXD10 homeobox D10 2.5463
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 2.54615
CCDC87 coiled-coil domain containing 87 2.5455
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 2.5435
RGSL1 regulator of G-protein signaling like 1 2.5311
HOXA3 homeobox A3 2.5242
GP1BA glycoprotein Ib (platelet), alpha polypeptide 2.52235
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 2.52035
INKA2 inka box actin regulator 2 2.51365
STARD8 StAR-related lipid transfer (START) domain containing 8 2.50575
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 2.49855
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic 2.48025
SLC14A2 solute carrier family 14 (urea transporter), member 2 2.4761
ATG3 autophagy related 3 2.47493
IL36R interleukin 36 receptor 2.47365
OPN1SW opsin 1 (cone pigments), short-wave-sensitive 2.4621
CTSL cathepsin L 2.4557
CHRND cholinergic receptor, nicotinic, delta (muscle) 2.45175
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) 2.4507
MC3R melanocortin 3 receptor 2.45005
GRK1 G protein-coupled receptor kinase 1 2.44675
ICAM1 intercellular adhesion molecule 1 2.44272
CABP5 calcium binding protein 5 2.43735
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 2.42965
BCL10 B-cell CLL/lymphoma 10 2.42675
TUBB6 tubulin, beta 6 class V 2.42145
SPATA6L spermatogenesis associated 6-like 2.4206
GJB4 gap junction protein, beta 4, 30.3kDa 2.4133
GNPDA1 glucosamine-6-phosphate deaminase 1 2.411
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 2.40275
GLRA2 glycine receptor, alpha 2 2.39895
ARHGAP24 Rho GTPase activating protein 24 2.3988
CSDC2 cold shock domain containing C2, RNA binding 2.3885
ST7L suppression of tumorigenicity 7 like 2.3865
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 2.379
KCNK7 potassium channel, two pore domain subfamily K, member 7 2.37705
TBC1D19 TBC1 domain family, member 19 2.3768
TSKU tsukushi, small leucine rich proteoglycan 2.37605
STXBP5L syntaxin binding protein 5-like 2.37475
DRD4 dopamine receptor D4 2.37315
CBR1 carbonyl reductase 1 2.37185
LONP2 lon peptidase 2, peroxisomal 2.36828
ADAM11 ADAM metallopeptidase domain 11 2.36465
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 2.36465
DNAH2 dynein, axonemal, heavy chain 2 2.36255
ARR3 arrestin 3, retinal (X-arrestin) 2.3611
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 2.36105
ADGRE5 adhesion G protein-coupled receptor E5 2.36075
UTP11 UTP11 small subunit processome component 2.35465
GLI1 GLI family zinc finger 1 2.35025
OR1A1 olfactory receptor, family 1, subfamily A, member 1 2.3438
KISS1 KiSS-1 metastasis-suppressor 2.3427
MCOLN1 mucolipin 1 2.33665
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 2.32315
ALX4 ALX homeobox 4 2.3162
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.31507
SSBP3 single stranded DNA binding protein 3 2.31445
NME8 NME/NM23 family member 8 2.3119
PCBP3 poly(rC) binding protein 3 2.30965
RRH retinal pigment epithelium-derived rhodopsin homolog 2.30165
UFM1 ubiquitin-fold modifier 1 2.2997
NQO1 NAD(P)H dehydrogenase, quinone 1 2.29742
PEX5L peroxisomal biogenesis factor 5-like 2.2894
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 2.2894
GML glycosylphosphatidylinositol anchored molecule like 2.28565
GNS glucosamine (N-acetyl)-6-sulfatase 2.28337
BMP10 bone morphogenetic protein 10 2.28085
PDE7B phosphodiesterase 7B 2.27885
TOM1 target of myb1 (chicken) 2.2766
FNDC8 fibronectin type III domain containing 8 2.27595
CST8 cystatin 8 (cystatin-related epididymal specific) 2.2753
GRIA4 glutamate receptor, ionotropic, AMPA 4 2.2617
KRT33B keratin 33B, type I 2.2587
GRIK3 glutamate receptor, ionotropic, kainate 3 2.25335
CRYBA4 crystallin, beta A4 2.25215
NEUROG1 neurogenin 1 2.25195
HEYL hes-related family bHLH transcription factor with YRPW motif-like 2.24805
CASR calcium-sensing receptor 2.24773
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 2.2472
NUP133 nucleoporin 133kDa 2.24595
OR1G1 olfactory receptor, family 1, subfamily G, member 1 2.2397
KLF1 Kruppel-like factor 1 (erythroid) 2.23525
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2 2.23327
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.23105
CCKAR cholecystokinin A receptor 2.2257
CCDC70 coiled-coil domain containing 70 2.224
PLIN3 perilipin 3 2.22225
NAPSA napsin A aspartic peptidase 2.22032
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 2.2199
LIF leukemia inhibitory factor 2.2189
COL11A1 collagen, type XI, alpha 1 2.21848
KRT32 keratin 32, type I 2.21765
ATG7 autophagy related 7 2.2159
OPN1MW3 opsin 1, medium wave sensitive 3 2.2133
ADAM30 ADAM metallopeptidase domain 30 2.213
CASC3 cancer susceptibility candidate 3 2.21255
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 2.20555
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1 2.20465
DLX6 distal-less homeobox 6 2.2041
RSPH14 radial spoke head 14 homolog (Chlamydomonas) 2.2035
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 2.20315
HAND2 heart and neural crest derivatives expressed 2 2.2026
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 2.20175
MPPED1 metallophosphoesterase domain containing 1 2.20135
PDE11A phosphodiesterase 11A 2.19785
TPSD1 tryptase delta 1 2.19585
EN2 engrailed homeobox 2 2.1944
TUB tubby bipartite transcription factor 2.19302
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 2.19185
IL1RAPL2 interleukin 1 receptor accessory protein-like 2 2.1909
BACE1 beta-site APP-cleaving enzyme 1 2.1907
HOXD9 homeobox D9 2.18295
DAND5 DAN domain family member 5, BMP antagonist 2.18285
CCDC30 coiled-coil domain containing 30 2.18275
AKAP3 A kinase (PRKA) anchor protein 3 2.18205
AMPD2 adenosine monophosphate deaminase 2 2.1811
MAPK14 mitogen-activated protein kinase 14 2.17784
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 2.1777
GJC2 gap junction protein, gamma 2, 47kDa 2.177
H2BC12 H2B clustered histone 12 2.17675
DCHS2 dachsous cadherin-related 2 2.1761
GCFC2 GC-rich sequence DNA-binding factor 2 2.17445
CSF3R colony stimulating factor 3 receptor (granulocyte) 2.17415
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 2.17365
DNM3 dynamin 3 2.1699
ADGRE3 adhesion G protein-coupled receptor E3 2.1697
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 2.168
SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4 2.165
GSTA3 glutathione S-transferase alpha 3 2.1644
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase 2.162
BAG2 BCL2-associated athanogene 2 2.1601
OR52A1 olfactory receptor, family 52, subfamily A, member 1 2.16
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 2.15875
SH3TC2 SH3 domain and tetratricopeptide repeats 2 2.1578
SYNGR4 synaptogyrin 4 2.1555
MAGEA6 melanoma antigen family A6 2.15532
SMAD9 SMAD family member 9 2.1552
MAP2K3 mitogen-activated protein kinase kinase 3 2.15443
OMP olfactory marker protein 2.15425
ATF7 activating transcription factor 7 2.1529
DPH2 DPH2 homolog (S. cerevisiae) 2.14885
GUCY1A2 guanylate cyclase 1, soluble, alpha 2 2.14405
IFNW1 interferon, omega 1 2.14395
MMP14 matrix metallopeptidase 14 (membrane-inserted) 2.14331
STX1A syntaxin 1A (brain) 2.14065
MAP3K11 mitogen-activated protein kinase kinase kinase 11 2.1388
IFNA7 interferon, alpha 7 2.13825
NPFFR1 neuropeptide FF receptor 1 2.136
CLCN5 chloride channel, voltage-sensitive 5 2.13355
SLC35F6 solute carrier family 35, member F6 2.1308
FSCN3 fascin actin-bundling protein 3, testicular 2.12875
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 2.12848
MAP3K19 mitogen-activated protein kinase kinase kinase 19 2.12165
GJD2 gap junction protein, delta 2, 36kDa 2.1196
CRYGB crystallin, gamma B 2.1185
PLPPR1 phospholipid phosphatase related 1 2.1169
IER2 immediate early response 2 2.11665
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.1135
COL19A1 collagen, type XIX, alpha 1 2.1067
TCEANC2 transcription elongation factor A (SII) N-terminal and central domain containing 2 2.1032
CDH22 cadherin 22, type 2 2.1007
TAAR5 trace amine associated receptor 5 2.09905
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 2.0978
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.09605
FPGT-TNNI3K FPGT-TNNI3K readthrough 2.09255
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like 2.09185
TBR1 T-box, brain, 1 2.0917
HRC histidine rich calcium binding protein 2.0905
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit 2.0893
VCY1B variable charge, Y-linked 1B 2.0875
LUZP4 leucine zipper protein 4 2.087
WNT16 wingless-type MMTV integration site family, member 16 2.0868
UBE2H ubiquitin-conjugating enzyme E2H 2.08588
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 2.08488
SEZ6L seizure related 6 homolog (mouse)-like 2.08476
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.0844
GYPB glycophorin B (MNS blood group) 2.0836
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) 2.08325
PRDM8 PR domain containing 8 2.0832
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 2.08295
LOC102725023 killer cell immunoglobulin-like receptor 2DS3 allele 0020101 2.08165
CDC45 cell division cycle 45 2.08155
BPI bactericidal/permeability-increasing protein 2.0814
SLC39A2 solute carrier family 39 (zinc transporter), member 2 2.0808
CLCN4 chloride channel, voltage-sensitive 4 2.0784
PDLIM7 PDZ and LIM domain 7 (enigma) 2.07839
TRIM49B tripartite motif containing 49B 2.0776
SARM1 sterile alpha and TIR motif containing 1 2.077
TSSK1B testis-specific serine kinase 1B 2.0747
TAS2R8 taste receptor, type 2, member 8 2.0743
FGF16 fibroblast growth factor 16 2.0741
ERN1 endoplasmic reticulum to nucleus signaling 1 2.0733
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 2.0727
GPC1 glypican 1 2.07165
ADAM20 ADAM metallopeptidase domain 20 2.0711
TNIP1 TNFAIP3 interacting protein 1 2.071
INSL6 insulin-like 6 2.0701
H3-4 H3.4 histone, cluster member 2.0696
TLR6 toll-like receptor 6 2.06935
NHLH1 nescient helix loop helix 1 2.0675
FPR1 formyl peptide receptor 1 2.0673
ZNF507 zinc finger protein 507 2.06635
LRIT1 leucine-rich repeat, immunoglobulin-like and transmembrane domains 1 2.06625
OR3A3 olfactory receptor, family 3, subfamily A, member 3 2.06515
MRPL37 mitochondrial ribosomal protein L37 2.065
VPREB3 pre-B lymphocyte 3 2.06165
BRMS1L breast cancer metastasis-suppressor 1-like 2.06155
ABI2 abl-interactor 2 2.06085
MBOAT7 membrane bound O-acyltransferase domain containing 7 2.05993
LIM2 lens intrinsic membrane protein 2, 19kDa 2.05665
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein 2.05305
RPAIN RPA interacting protein 2.053
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 2.05175
DOCK5 dedicator of cytokinesis 5 2.05155
AKR1C3 aldo-keto reductase family 1, member C3 2.0506
QPCTL glutaminyl-peptide cyclotransferase-like 2.0493
RPH3A rabphilin 3A 2.04925
GTF2IRD2B GTF2I repeat domain containing 2B 2.04865
FOLR3 folate receptor 3 (gamma) 2.04805
NTSR1 neurotensin receptor 1 (high affinity) 2.0453
CD101 CD101 molecule 2.0437
ZFR2 zinc finger RNA binding protein 2 2.0421
MROH7 maestro heat-like repeat family member 7 2.04015
TFDP3 transcription factor Dp family, member 3 2.0369
RARB retinoic acid receptor, beta 2.03474
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 2.0343
RNASE12 ribonuclease, RNase A family, 12 (non-active) 2.0338
NADK NAD kinase 2.03171
H2BC17 H2B clustered histone 17 2.03075
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 2.0291
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 2.02892
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 2.02885
METTL16 methyltransferase like 16 2.0267
TXNL1 thioredoxin-like 1 2.02585
ZNF442 zinc finger protein 442 2.0254
OXCT2 3-oxoacid CoA transferase 2 2.0213
CDON cell adhesion associated, oncogene regulated 2.02045
HCRT hypocretin (orexin) neuropeptide precursor 2.01995
ALX1 ALX homeobox 1 2.0189
DUSP13A dual specificity phosphatase 13A 2.01715
BTNL2 butyrophilin-like 2 2.0168
MRPL24 mitochondrial ribosomal protein L24 2.0156
MIMS2 mitochondrial inner membrane scaffold 2 2.01545
EPB42 erythrocyte membrane protein band 4.2 2.0148
SH2B3 SH2B adaptor protein 3 2.0138
MNDA myeloid cell nuclear differentiation antigen 2.01355
AGTR2 angiotensin II receptor, type 2 2.01212
SMAD3 SMAD family member 3 2.01145
ADRA1D adrenoceptor alpha 1D 2.0107
DTNB dystrobrevin, beta 2.01043
ZNF585B zinc finger protein 585B 2.0085
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.00745
PHAF1 phagosome assembly factor 1 2.00625
OPRM1 opioid receptor, mu 1 2.00513
TGM2 transglutaminase 2 2.00467
LY6G5C lymphocyte antigen 6 complex, locus G5C 2.00265
KCTD11 potassium channel tetramerization domain containing 11 2.00265
PRDM11 PR domain containing 11 2.0024
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) 2.00207
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 2.00055

decreased expression

Symbol Name Standardized Value
TCTN1 tectonic family member 1 -5.45505
CASP7 caspase 7, apoptosis-related cysteine peptidase -5.19955
TRIB3 tribbles pseudokinase 3 -5.08165
CCNB2 cyclin B2 -5.06965
CASP3 caspase 3, apoptosis-related cysteine peptidase -5.06405
DSG2 desmoglein 2 -4.8716
VAT1 vesicle amine transport 1 -4.86915
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.80355
AURKB aurora kinase B -4.76015
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -4.74275
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -4.70525
GTPBP8 GTP-binding protein 8 (putative) -4.6449
PGM1 phosphoglucomutase 1 -4.5543
PSRC1 proline/serine-rich coiled-coil 1 -4.47885
MAP7 microtubule-associated protein 7 -4.34182
NGRN neugrin, neurite outgrowth associated -4.3136
MRPS2 mitochondrial ribosomal protein S2 -4.2915
RPS4Y1 ribosomal protein S4, Y-linked 1 -4.0331
KDM3A lysine (K)-specific demethylase 3A -3.8009
ERBB2 erb-b2 receptor tyrosine kinase 2 -3.78822
ADI1 acireductone dioxygenase 1 -3.67265
CAB39 calcium binding protein 39 -3.6642
FHL2 four and a half LIM domains 2 -3.65905
DDIT4 DNA-damage-inducible transcript 4 -3.60885
GNAS GNAS complex locus -3.54906
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.46575
DHRS7 dehydrogenase/reductase (SDR family) member 7 -3.40275
AZGP1 alpha-2-glycoprotein 1, zinc-binding -3.11905
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -3.0726
KLHDC2 kelch domain containing 2 -3.042
GMNN geminin, DNA replication inhibitor -3.0234
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -3.0022
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.00138
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.98925
DCK deoxycytidine kinase -2.97365
ACAA1 acetyl-CoA acyltransferase 1 -2.90105
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -2.88615
CPE carboxypeptidase E -2.80753
ECH1 enoyl CoA hydratase 1, peroxisomal -2.76795
MSMO1 methylsterol monooxygenase 1 -2.76135
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.726
PEBP1 phosphatidylethanolamine binding protein 1 -2.7248
ESRP1 epithelial splicing regulatory protein 1 -2.72325
STMN1 stathmin 1 -2.6898
KIF2C kinesin family member 2C -2.6041
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.55785
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -2.48815
PROS1 protein S (alpha) -2.41235
SELENOW selenoprotein W -2.4063
CCNB1 cyclin B1 -2.40345
NTAN1 N-terminal asparagine amidase -2.39473
SESN1 sestrin 1 -2.39005
HADH hydroxyacyl-CoA dehydrogenase -2.38395
PRKX protein kinase, X-linked -2.37748
AMDHD2 amidohydrolase domain containing 2 -2.36815
CBR4 carbonyl reductase 4 -2.3404
SOAT2 sterol O-acyltransferase 2 -2.3117
VAV3 vav 3 guanine nucleotide exchange factor -2.2807
ACVR2B activin A receptor, type IIB -2.25775
GGCT gamma-glutamylcyclotransferase -2.24675
MTERF3 mitochondrial transcription termination factor 3 -2.2388
FXYD1 FXYD domain containing ion transport regulator 1 -2.23495
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 -2.23045
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -2.22955
RABAC1 Rab acceptor 1 (prenylated) -2.2169
MAPK9 mitogen-activated protein kinase 9 -2.20023
MAPK13 mitogen-activated protein kinase 13 -2.19055
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.1841
RASA2 RAS p21 protein activator 2 -2.1778
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -2.1772
SCD stearoyl-CoA desaturase (delta-9-desaturase) -2.17021
GDF15 growth differentiation factor 15 -2.1673
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -2.15715
CHEK2 checkpoint kinase 2 -2.15615
ITGB1BP1 integrin beta 1 binding protein 1 -2.1523
PPP1R26 protein phosphatase 1, regulatory subunit 26 -2.13075
NUP85 nucleoporin 85kDa -2.1161
RAD51C RAD51 paralog C -2.11555
NELFB negative elongation factor complex member B -2.11225
H1-10 H1.10 linker histone -2.1095
PLK1 polo-like kinase 1 -2.1048
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -2.10125
DPYSL2 dihydropyrimidinase-like 2 -2.08025
CDC25B cell division cycle 25B -2.07975
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -2.07595
RFC2 replication factor C (activator 1) 2, 40kDa -2.07315
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -2.07105
COX17 COX17 cytochrome c oxidase copper chaperone -2.06885
HMGN3 high mobility group nucleosomal binding domain 3 -2.0667
CAPRIN2 caprin family member 2 -2.06625
TCEA2 transcription elongation factor A (SII), 2 -2.06505
DHCR24 24-dehydrocholesterol reductase -2.0649
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -2.0621
FN3KRP fructosamine 3 kinase related protein -2.05655
HOXA5 homeobox A5 -2.04615
SYNGR2 synaptogyrin 2 -2.0422
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -2.03915
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -2.03095
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -2.0194
TMSB10 thymosin beta 10 -2.0123