CRCGN011_HEPG2_24H:I23 Gene Set
Genes
53 genes differentially expressed following the CRCGN011_HEPG2_24H:I23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
9.03075
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
5.32975
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
5.01325
|
|
RPL39L
|
ribosomal protein L39-like
|
4.73665
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.6964
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.6205
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.18905
|
|
ABHD6
|
abhydrolase domain containing 6
|
4.1733
|
|
HDGFL3
|
HDGF like 3
|
4.06951
|
|
CDK2
|
cyclin-dependent kinase 2
|
4.02575
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
3.68622
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.2079
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
2.5976
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.58145
|
|
BHLHE41
|
basic helix-loop-helix family, member e41
|
2.4644
|
|
BAMBI
|
BMP and activin membrane-bound inhibitor
|
2.33845
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.32975
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.29753
|
|
ANAPC10
|
anaphase promoting complex subunit 10
|
2.26355
|
|
TTC27
|
tetratricopeptide repeat domain 27
|
2.2452
|
|
CXCL1
|
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
|
2.20585
|
|
ADAM10
|
ADAM metallopeptidase domain 10
|
2.19207
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.1721
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.16085
|
|
CXCL8
|
chemokine (C-X-C motif) ligand 8
|
2.1459
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
GNAS
|
GNAS complex locus
|
-7.27534
|
|
TRIB3
|
tribbles pseudokinase 3
|
-5.2134
|
|
THAP11
|
THAP domain containing 11
|
-5.20785
|
|
GDF15
|
growth differentiation factor 15
|
-4.955
|
|
BMP4
|
bone morphogenetic protein 4
|
-4.8472
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.71785
|
|
CDC20
|
cell division cycle 20
|
-4.2155
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.97385
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-3.938
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.65205
|
|
RGS2
|
regulator of G-protein signaling 2
|
-3.3699
|
|
GRB14
|
growth factor receptor-bound protein 14
|
-2.59635
|
|
CCNB2
|
cyclin B2
|
-2.4529
|
|
E4F1
|
E4F transcription factor 1
|
-2.34605
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
-2.34325
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.31765
|
|
LAG3
|
lymphocyte-activation gene 3
|
-2.2972
|
|
RNF167
|
ring finger protein 167
|
-2.20535
|
|
RBM15B
|
RNA binding motif protein 15B
|
-2.17875
|
|
WASHC4
|
WASH complex subunit 4
|
-2.17683
|
|
GTPBP2
|
GTP binding protein 2
|
-2.17505
|
|
EIF2AK1
|
eukaryotic translation initiation factor 2-alpha kinase 1
|
-2.16618
|
|
RECQL4
|
RecQ protein-like 4
|
-2.0967
|
|
MORC3
|
MORC family CW-type zinc finger 3
|
-2.094
|
|
CRB1
|
crumbs family member 1, photoreceptor morphogenesis associated
|
-2.0857
|
|
RNF31
|
ring finger protein 31
|
-2.06525
|
|
FOLH1
|
folate hydrolase (prostate-specific membrane antigen) 1
|
-2.03557
|
|
TINF2
|
TERF1 (TRF1)-interacting nuclear factor 2
|
-2.0131
|
