| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2,4,5-trimethylaniline 10.76 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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100 genes differentially expressed following the CRCGN011_HEPG2_24H:J08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 7.63915 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 5.5929 |
| CCL2 | chemokine (C-C motif) ligand 2 | 5.56935 |
| JADE2 | jade family PHD finger 2 | 5.26753 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 5.26315 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 4.99245 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 4.5947 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 4.46885 |
| GATA3 | GATA binding protein 3 | 3.94437 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 3.5187 |
| SNX7 | sorting nexin 7 | 3.4731 |
| TLR4 | toll-like receptor 4 | 3.2731 |
| CHN1 | chimerin 1 | 3.2711 |
| TENT4A | terminal nucleotidyltransferase 4A | 3.1017 |
| CEP57 | centrosomal protein 57kDa | 3.05467 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 2.9917 |
| MMP2 | matrix metallopeptidase 2 | 2.93915 |
| CCNF | cyclin F | 2.89545 |
| ADGRL4 | adhesion G protein-coupled receptor L4 | 2.83385 |
| NMU | neuromedin U | 2.74635 |
| EED | embryonic ectoderm development | 2.66795 |
| PSMA1 | proteasome (prosome, macropain) subunit, alpha type, 1 | 2.61217 |
| ANKRD49 | ankyrin repeat domain 49 | 2.5225 |
| EDN1 | endothelin 1 | 2.3877 |
| ATP11B | ATPase, class VI, type 11B | 2.37495 |
| MRPL39 | mitochondrial ribosomal protein L39 | 2.3248 |
| TESK1 | testis-specific kinase 1 | 2.3004 |
| FZD1 | frizzled class receptor 1 | 2.29047 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | 2.2743 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 2.26657 |
| HIKESHI | heat shock protein nuclear import factor hikeshi | 2.24755 |
| NDC80 | NDC80 kinetochore complex component | 2.24575 |
| CYCS | cytochrome c, somatic | 2.24505 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 2.2448 |
| RAI14 | retinoic acid induced 14 | 2.24225 |
| TMEM126B | transmembrane protein 126B | 2.2235 |
| H2BC21 | H2B clustered histone 21 | 2.21115 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 2.20395 |
| BAMBI | BMP and activin membrane-bound inhibitor | 2.20125 |
| RLN1 | relaxin 1 | 2.1849 |
| CNN3 | calponin 3, acidic | 2.1668 |
| P2RY4 | pyrimidinergic receptor P2Y, G-protein coupled, 4 | 2.1546 |
| ANKRD12 | ankyrin repeat domain 12 | 2.13067 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 2.1234 |
| GNLY | granulysin | 2.1013 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 2.0903 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | 2.08678 |
| ILK | integrin-linked kinase | 2.06075 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 2.0568 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) | 2.0427 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.03865 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 2.02733 |
| NUBP2 | nucleotide binding protein 2 | 2.02655 |
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | 2.02185 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | 2.00585 |
| EMCN | endomucin | 2.0055 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -6.17835 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -5.7521 |
| NUP93 | nucleoporin 93kDa | -5.6818 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.9525 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -4.5252 |
| FGFR4 | fibroblast growth factor receptor 4 | -4.50665 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -4.4413 |
| MAP7 | microtubule-associated protein 7 | -4.2943 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -3.9226 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | -3.81855 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.6856 |
| GDF15 | growth differentiation factor 15 | -3.55575 |
| DERA | deoxyribose-phosphate aldolase (putative) | -3.44935 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -3.44475 |
| GNAS | GNAS complex locus | -3.38624 |
| MRPS2 | mitochondrial ribosomal protein S2 | -2.98545 |
| FBXO7 | F-box protein 7 | -2.8232 |
| YME1L1 | YME1-like 1 ATPase | -2.77898 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -2.7693 |
| HEATR1 | HEAT repeat containing 1 | -2.5736 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.4703 |
| CIRBP | cold inducible RNA binding protein | -2.43135 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.40179 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -2.39615 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -2.36005 |
| CDK6 | cyclin-dependent kinase 6 | -2.35875 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | -2.3181 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -2.29825 |
| PARP1 | poly (ADP-ribose) polymerase 1 | -2.2465 |
| PLOD3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | -2.2422 |
| MALT1 | MALT1 paracaspase | -2.22523 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | -2.2147 |
| TRAP1 | TNF receptor-associated protein 1 | -2.18075 |
| SPOUT1 | SPOUT domain containing methyltransferase 1 | -2.1282 |
| TBC1D10C | TBC1 domain family, member 10C | -2.12795 |
| SCAMP2 | secretory carrier membrane protein 2 | -2.11635 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | -2.1144 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.08273 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 | -2.07595 |
| BAHD1 | bromo adjacent homology domain containing 1 | -2.062 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | -2.0226 |
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | -2.0184 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 | -2.01447 |
| HOXA5 | homeobox A5 | -2.01125 |
