CRCGN011_HEPG2_24H:J13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

1025 genes differentially expressed following the CRCGN011_HEPG2_24H:J13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
LCN2 lipocalin 2 6.33685
MYLK myosin light chain kinase 6.32305
MCOLN1 mucolipin 1 6.2656
RPP38 ribonuclease P/MRP 38kDa subunit 5.7708
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 5.48995
MAMLD1 mastermind-like domain containing 1 5.17655
CDPF1 cysteine-rich, DPF motif domain containing 1 5.1313
ANO1 anoctamin 1, calcium activated chloride channel 5.0
BDH1 3-hydroxybutyrate dehydrogenase, type 1 4.4957
PTPN6 protein tyrosine phosphatase, non-receptor type 6 4.3785
ADGRE5 adhesion G protein-coupled receptor E5 4.37635
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 4.31435
CCDC92 coiled-coil domain containing 92 4.1911
CCDC85B coiled-coil domain containing 85B 4.18555
C2CD2 C2 calcium-dependent domain containing 2 4.17365
KLHL21 kelch-like family member 21 4.15175
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) 4.0645
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 4.0384
GRWD1 glutamate-rich WD repeat containing 1 4.0099
E2F2 E2F transcription factor 2 3.79275
ADD3 adducin 3 (gamma) 3.76465
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4 3.75495
IL3RA interleukin 3 receptor, alpha (low affinity) 3.734
CBR1 carbonyl reductase 1 3.72505
OXCT1 3-oxoacid CoA transferase 1 3.7127
ANO10 anoctamin 10 3.65585
MSRA methionine sulfoxide reductase A 3.6443
SQOR sulfide quinone oxidoreductase 3.5851
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 3.5718
CHMP6 charged multivesicular body protein 6 3.55835
COMMD3-BMI1 COMMD3-BMI1 readthrough 3.55555
PGLYRP1 peptidoglycan recognition protein 1 3.546
TNP1 transition protein 1 (during histone to protamine replacement) 3.5331
ADRB3 adrenoceptor beta 3 3.51972
RSU1 Ras suppressor protein 1 3.49325
HCAR3 hydroxycarboxylic acid receptor 3 3.47335
FOSL1 FOS-like antigen 1 3.45445
CYCS cytochrome c, somatic 3.454
EDN1 endothelin 1 3.4534
PCDHGA5 protocadherin gamma subfamily A, 5 3.41095
GSTM2 glutathione S-transferase mu 2 (muscle) 3.4061
TRIM13 tripartite motif containing 13 3.3731
CCNO cyclin O 3.3636
GSTT4 glutathione S-transferase theta 4 3.3506
TNS2 tensin 2 3.34685
DOCK5 dedicator of cytokinesis 5 3.34545
FEV FEV (ETS oncogene family) 3.2987
ELP3 elongator acetyltransferase complex subunit 3 3.2982
GATA3 GATA binding protein 3 3.27193
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3.26335
ATG2A autophagy related 2A 3.25455
PFKL phosphofructokinase, liver 3.25183
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 3.24978
MIER2 mesoderm induction early response 1, family member 2 3.24513
PRB2 proline-rich protein BstNI subfamily 2 3.243
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4 3.24265
LTF lactotransferrin 3.23475
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 3.2286
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 3.2238
TIMP2 TIMP metallopeptidase inhibitor 2 3.21835
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 3.19945
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 3.19085
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa 3.1907
SOX21 SRY (sex determining region Y)-box 21 3.1793
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 3.1684
SYNGAP1 synaptic Ras GTPase activating protein 1 3.1649
SYNE2 spectrin repeat containing, nuclear envelope 2 3.16165
BIN2 bridging integrator 2 3.15935
DUSP2 dual specificity phosphatase 2 3.1558
SNX7 sorting nexin 7 3.1534
STK10 serine/threonine kinase 10 3.14547
SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4 3.1311
VGLL4 vestigial-like family member 4 3.11007
DPH2 DPH2 homolog (S. cerevisiae) 3.10915
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 3.1091
SMYD3 SET and MYND domain containing 3 3.10615
TRAK2 trafficking protein, kinesin binding 2 3.09825
TCEANC2 transcription elongation factor A (SII) N-terminal and central domain containing 2 3.09375
MYLIP myosin regulatory light chain interacting protein 3.08315
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 3.0744
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 3.07285
NGRN neugrin, neurite outgrowth associated 3.0708
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 3.06385
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 3.0589
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 3.05715
GAS1 growth arrest-specific 1 3.0489
RPL39L ribosomal protein L39-like 3.04695
CRTAP cartilage associated protein 3.0456
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 3.0328
CCDC57 coiled-coil domain containing 57 3.0304
OLFML2B olfactomedin-like 2B 3.02375
SLC38A12 solute carrier family 38 member 12 3.0228
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 3.02005
VRK2 vaccinia related kinase 2 3.01865
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 3.00927
PRDM1 PR domain containing 1, with ZNF domain 2.9969
POU5F1 POU class 5 homeobox 1 2.98962
UPK2 uroplakin 2 2.988
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 2.98405
TREM1 triggering receptor expressed on myeloid cells 1 2.9808
ADNP activity-dependent neuroprotector homeobox 2.97475
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 2.97375
LAGE3 L antigen family, member 3 2.9708
SMCP sperm mitochondria-associated cysteine-rich protein 2.9697
TGM5 transglutaminase 5 2.96395
CDKL2 cyclin-dependent kinase-like 2 (CDC2-related kinase) 2.95425
TESPA1 thymocyte expressed, positive selection associated 1 2.94915
PRKCQ protein kinase C, theta 2.9392
STK17B serine/threonine kinase 17b 2.93287
TP53TG5 TP53 target 5 2.9311
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 2.93022
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 2.92825
CD69 CD69 molecule 2.92705
KLHL11 kelch-like family member 11 2.9205
PGLYRP4 peptidoglycan recognition protein 4 2.90705
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 2.8983
MPHOSPH8 M-phase phosphoprotein 8 2.89685
CNGA1 cyclic nucleotide gated channel alpha 1 2.89505
SLC35E2B solute carrier family 35, member E2B 2.88265
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 2.87935
PER1 period circadian clock 1 2.86635
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 2.8641
CTC1 CTS telomere maintenance complex component 1 2.86155
RAB3IL1 RAB3A interacting protein (rabin3)-like 1 2.8561
PLA2G2F phospholipase A2, group IIF 2.8546
PRSS53 protease, serine, 53 2.8464
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.8385
STAT4 signal transducer and activator of transcription 4 2.83835
CCDC70 coiled-coil domain containing 70 2.83175
PRKCH protein kinase C, eta 2.8281
CA12 carbonic anhydrase XII 2.81085
PEX11A peroxisomal biogenesis factor 11 alpha 2.80755
H1-1 H1.1 linker histone, cluster member 2.80645
ZPBP zona pellucida binding protein 2.8042
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 2.8037
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma 2.8013
PODXL podocalyxin-like 2.79745
ACO2 aconitase 2, mitochondrial 2.7944
FGF17 fibroblast growth factor 17 2.79285
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 2.79175
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 2.79153
VEGFC vascular endothelial growth factor C 2.79055
CLUH clustered mitochondria (cluA/CLU1) homolog 2.79045
ZNRF4 zinc and ring finger 4 2.7889
RTN3 reticulon 3 2.7886
MMP8 matrix metallopeptidase 8 2.7886
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 2.7883
SDF4 stromal cell derived factor 4 2.7875
CYTIP cytohesin 1 interacting protein 2.786
MXD1 MAX dimerization protein 1 2.7821
CA8 carbonic anhydrase VIII 2.78015
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 2.7778
AKAP4 A kinase (PRKA) anchor protein 4 2.77445
AQP6 aquaporin 6, kidney specific 2.77355
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 2.77262
UPK1B uroplakin 1B 2.77073
GJD2 gap junction protein, delta 2, 36kDa 2.7669
ITK IL2-inducible T-cell kinase 2.7668
WT1 Wilms tumor 1 2.76658
EGR4 early growth response 4 2.76312
GHR growth hormone receptor 2.762
UNC5C unc-5 homolog C (C. elegans) 2.76075
CD248 CD248 molecule, endosialin 2.7584
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 2.75817
ADGRB1 adhesion G protein-coupled receptor B1 2.7508
ATF7 activating transcription factor 7 2.74895
PORCN porcupine homolog (Drosophila) 2.7472
ODF1 outer dense fiber of sperm tails 1 2.7455
INPP5J inositol polyphosphate-5-phosphatase J 2.7447
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.74285
IFNG interferon, gamma 2.74235
LAX1 lymphocyte transmembrane adaptor 1 2.7406
OR2H1 olfactory receptor, family 2, subfamily H, member 1 2.7403
SSBP3 single stranded DNA binding protein 3 2.7393
LSM1 LSM1, U6 small nuclear RNA associated 2.739
PRB4 proline-rich protein BstNI subfamily 4 2.7385
GPR143 G protein-coupled receptor 143 2.7328
COL11A1 collagen, type XI, alpha 1 2.73235
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 2.73046
FHIT fragile histidine triad 2.7286
GFI1 growth factor independent 1 transcription repressor 2.72795
ALOXE3 arachidonate lipoxygenase 3 2.72502
ACTL7B actin-like 7B 2.7239
TATDN2 TatD DNase domain containing 2 2.7235
NAT10 N-acetyltransferase 10 (GCN5-related) 2.72335
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 2.7232
ALDOC aldolase C, fructose-bisphosphate 2.72255
SOCS4 suppressor of cytokine signaling 4 2.72195
CALM3 calmodulin 3 (phosphorylase kinase, delta) 2.71982
MNMIP1 manchette microtubule inner protein 1 2.7103
RECQL4 RecQ protein-like 4 2.7076
ACOT9 acyl-CoA thioesterase 9 2.7025
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 2.70045
ZNF132 zinc finger protein 132 2.699
SZT2 seizure threshold 2 homolog (mouse) 2.6978
DENND1C DENN/MADD domain containing 1C 2.69755
WDTC1 WD and tetratricopeptide repeats 1 2.69355
TIAM1 T-cell lymphoma invasion and metastasis 1 2.69193
TBC1D16 TBC1 domain family, member 16 2.6913
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled 2.68715
RNF125 ring finger protein 125, E3 ubiquitin protein ligase 2.68565
DUSP14 dual specificity phosphatase 14 2.67845
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1 2.6779
NENF neudesin neurotrophic factor 2.67555
SLC26A4 solute carrier family 26 (anion exchanger), member 4 2.6747
PDE2A phosphodiesterase 2A, cGMP-stimulated 2.6744
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic 2.66885
EYA2 EYA transcriptional coactivator and phosphatase 2 2.66235
ZNF280B zinc finger protein 280B 2.66225
E2F6 E2F transcription factor 6 2.6616
BCL7B B-cell CLL/lymphoma 7B 2.6615
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 2.65945
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 2.65315
DDN dendrin 2.65305
PRB3 proline-rich protein BstNI subfamily 3 2.65235
CST7 cystatin F (leukocystatin) 2.64785
NCK2 NCK adaptor protein 2 2.6477
WDR4 WD repeat domain 4 2.64635
PPARG peroxisome proliferator-activated receptor gamma 2.645
ZBTB25 zinc finger and BTB domain containing 25 2.6322
CHODL chondrolectin 2.62435
RESF1 retroelement silencing factor 1 2.6222
SORBS1 sorbin and SH3 domain containing 1 2.62195
AFG3L2 AFG3-like AAA ATPase 2 2.6217
ZNF324B zinc finger protein 324B 2.61435
TSEN2 TSEN2 tRNA splicing endonuclease subunit 2.6133
PRSS21 protease, serine, 21 (testisin) 2.61025
CLUL1 clusterin-like 1 (retinal) 2.5966
FTH1 ferritin, heavy polypeptide 1 2.5965
TCTN1 tectonic family member 1 2.59625
TMEM187 transmembrane protein 187 2.59515
TP73 tumor protein p73 2.59045
LRRC37A3 leucine rich repeat containing 37, member A3 2.5869
LY75-CD302 LY75-CD302 readthrough 2.58575
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 2.58512
EML3 echinoderm microtubule associated protein like 3 2.5839
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 2.5739
HNF1B HNF1 homeobox B 2.57237
GAA glucosidase, alpha; acid 2.56835
COL6A1 collagen, type VI, alpha 1 2.56597
FNDC8 fibronectin type III domain containing 8 2.56575
NXF3 nuclear RNA export factor 3 2.56155
RENBP renin binding protein 2.5563
CNGB3 cyclic nucleotide gated channel beta 3 2.5563
BRDT bromodomain, testis-specific 2.5553
ZDHHC6 zinc finger, DHHC-type containing 6 2.5546
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) 2.5541
IL18R1 interleukin 18 receptor 1 2.5522
FOXD1 forkhead box D1 2.55095
MALT1 MALT1 paracaspase 2.54715
AURKA aurora kinase A 2.54672
BTG3 BTG family, member 3 2.5465
LRRK1 leucine-rich repeat kinase 1 2.54115
PHF7 PHD finger protein 7 2.53385
MMP9 matrix metallopeptidase 9 2.5299
COMMD3 COMM domain containing 3 2.52875
CPT1A carnitine palmitoyltransferase 1A (liver) 2.52704
MBD1 methyl-CpG binding domain protein 1 2.52655
DUSP4 dual specificity phosphatase 4 2.52358
IQGAP1 IQ motif containing GTPase activating protein 1 2.52127
VCX3A variable charge, X-linked 3A 2.51635
CBY1 chibby homolog 1 (Drosophila) 2.51615
KIF5C kinesin family member 5C 2.5137
SPATA31A3 SPATA31 subfamily A, member 3 2.5096
EMSY EMSY transcriptional repressor, BRCA2 interacting 2.5081
PARD6B par-6 family cell polarity regulator beta 2.50325
CRISP2 cysteine-rich secretory protein 2 2.50245
GARRE1 granule associated Rac and RHOG effector 1 2.50135
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 2.50065
CCND3 cyclin D3 2.49835
CASS4 Cas scaffolding protein family member 4 2.49775
ALPG alkaline phosphatase, germ cell 2.49408
MRPL17 mitochondrial ribosomal protein L17 2.4902
GPAA1 glycosylphosphatidylinositol anchor attachment 1 2.4901
DEPTOR DEP domain containing MTOR-interacting protein 2.4841
PKD2L1 polycystic kidney disease 2-like 1 2.4818
OXT oxytocin/neurophysin I prepropeptide 2.4772
MYCBP MYC binding protein 2.4763
PDE1B phosphodiesterase 1B, calmodulin-dependent 2.4749
SMIM8 small integral membrane protein 8 2.4742
CALB1 calbindin 1, 28kDa 2.4719
TSSK1B testis-specific serine kinase 1B 2.4675
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 2.4643
ADIPOR1 adiponectin receptor 1 2.46195
NSD1 nuclear receptor binding SET domain protein 1 2.46065
INPP1 inositol polyphosphate-1-phosphatase 2.4593
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 2.45885
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 2.45755
XPC xeroderma pigmentosum, complementation group C 2.4571
NEU2 sialidase 2 (cytosolic sialidase) 2.45625
GNG13 guanine nucleotide binding protein (G protein), gamma 13 2.45605
CYTH2 cytohesin 2 2.4503
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 2.44835
ERCC5 excision repair cross-complementation group 5 2.44095
STXBP1 syntaxin binding protein 1 2.43945
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 2.43575
CEP131 centrosomal protein 131kDa 2.4357
DEFA4 defensin, alpha 4, corticostatin 2.43535
IRAK3 interleukin-1 receptor-associated kinase 3 2.43155
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 2.429
PAX7 paired box 7 2.42825
CTSV cathepsin V 2.4282
TRAT1 T cell receptor associated transmembrane adaptor 1 2.4271
ZNF14 zinc finger protein 14 2.42395
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 2.4216
USF2 upstream transcription factor 2, c-fos interacting 2.4209
PEAK1 pseudopodium-enriched atypical kinase 1 2.4201
BLTP1 bridge-like lipid transfer protein family member 1 2.41663
RBKS ribokinase 2.4146
CYTH1 cytohesin 1 2.40965
GNB5 guanine nucleotide binding protein (G protein), beta 5 2.4074
OTULINL OTU deubiquitinase with linear linkage specificity like 2.40573
MEN1 multiple endocrine neoplasia I 2.4053
NNT nicotinamide nucleotide transhydrogenase 2.4051
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 2.40165
HOXC8 homeobox C8 2.4011
MTREX Mtr4 exosome RNA helicase 2.3975
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.39705
ZNF124 zinc finger protein 124 2.3944
KIFBP kinesin family binding protein 2.39255
PHACTR1 phosphatase and actin regulator 1 2.38855
GLG1 golgi glycoprotein 1 2.38842
SH2D1A SH2 domain containing 1A 2.38734
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 2.38535
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit 2.38415
NT5E 5'-nucleotidase, ecto (CD73) 2.3824
UBE2L6 ubiquitin-conjugating enzyme E2L 6 2.38205
DKKL1 dickkopf-like 1 2.382
CCL5 chemokine (C-C motif) ligand 5 2.37978
ARHGAP22 Rho GTPase activating protein 22 2.37925
GPR183 G protein-coupled receptor 183 2.3787
FAM153A family with sequence similarity 153, member A 2.37597
EMP3 epithelial membrane protein 3 2.37375
APOL6 apolipoprotein L, 6 2.37165
ZBTB3 zinc finger and BTB domain containing 3 2.37085
H2BC6 H2B clustered histone 6 2.37015
EREG epiregulin 2.3671
CRTAM cytotoxic and regulatory T cell molecule 2.3652
UBQLN2 ubiquilin 2 2.36445
CASP2 caspase 2, apoptosis-related cysteine peptidase 2.36253
SCUBE2 signal peptide, CUB domain, EGF-like 2 2.3588
CRH corticotropin releasing hormone 2.357
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 2.35692
PLAAT4 phospholipase A and acyltransferase 4 2.35395
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.3531
POFUT1 protein O-fucosyltransferase 1 2.35145
GLI3 GLI family zinc finger 3 2.34885
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2 2.3461
TSC22D3 TSC22 domain family, member 3 2.34573
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z 2.3451
SPATA31C1 SPATA31 subfamily C, member 1 2.3414
SPAG4 sperm associated antigen 4 2.3405
CPTP ceramide-1-phosphate transfer protein 2.34025
HOXA1 homeobox A1 2.3401
RIN1 Ras and Rab interactor 1 2.33945
MAP3K19 mitogen-activated protein kinase kinase kinase 19 2.33935
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein 2.3337
GJA8 gap junction protein, alpha 8, 50kDa 2.3292
DDR1 discoidin domain receptor tyrosine kinase 1 2.32811
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae) 2.32715
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 2.327
ACTL7A actin-like 7A 2.32465
CLIP3 CAP-GLY domain containing linker protein 3 2.3231
CPM carboxypeptidase M 2.32295
P2RY10 purinergic receptor P2Y, G-protein coupled, 10 2.32215
CBR3 carbonyl reductase 3 2.32085
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 2.31905
BACE2 beta-site APP-cleaving enzyme 2 2.31635
IQSEC3 IQ motif and Sec7 domain 3 2.3154
PTPRR protein tyrosine phosphatase, receptor type, R 2.3141
TRIM44 tripartite motif containing 44 2.31348
CHRDL1 chordin-like 1 2.3133
POM121L2 POM121 transmembrane nucleoporin-like 2 2.30985
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 2.3098
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 2.30903
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 2.30335
CTBP2 C-terminal binding protein 2 2.30215
CSAG2 CSAG family, member 2 2.3005
IL1B interleukin 1, beta 2.2986
ARFIP2 ADP-ribosylation factor interacting protein 2 2.2976
ZNHIT3 zinc finger, HIT-type containing 3 2.29585
CCDC7 coiled-coil domain containing 7 2.2948
INKA2 inka box actin regulator 2 2.294
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) 2.2924
AKAP5 A kinase (PRKA) anchor protein 5 2.28995
CORT cortistatin 2.28835
MTNR1A melatonin receptor 1A 2.28815
PHF10 PHD finger protein 10 2.28815
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 2.28805
CBX2 chromobox homolog 2 2.28715
GPR171 G protein-coupled receptor 171 2.2857
TOM1L2 target of myb1-like 2 (chicken) 2.28415
OXSM 3-oxoacyl-ACP synthase, mitochondrial 2.28305
TMEM59 transmembrane protein 59 2.28015
SH2D2A SH2 domain containing 2A 2.2798
FLRT1 fibronectin leucine rich transmembrane protein 1 2.27745
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 2.2771
TCN2 transcobalamin II 2.2764
HYAL4 hyaluronoglucosaminidase 4 2.27635
IBSP integrin-binding sialoprotein 2.27485
HDGFL3 HDGF like 3 2.27338
NCOA6 nuclear receptor coactivator 6 2.2727
ACSBG2 acyl-CoA synthetase bubblegum family member 2 2.27245
PES1 pescadillo ribosomal biogenesis factor 1 2.2701
PCDHGA9 protocadherin gamma subfamily A, 9 2.26775
THY1 Thy-1 cell surface antigen 2.26728
OVOL2 ovo-like zinc finger 2 2.26685
ADCY8 adenylate cyclase 8 (brain) 2.2613
PRDX4 peroxiredoxin 4 2.26045
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 2.2594
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.2589
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2 2.25885
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 2.25515
TENT5C terminal nucleotidyltransferase 5C 2.25355
PRDM8 PR domain containing 8 2.2523
LYRM1 LYR motif containing 1 2.2505
PDGFRB platelet-derived growth factor receptor, beta polypeptide 2.24835
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) 2.2446
SOX1 SRY (sex determining region Y)-box 1 2.24365
IFNA13 interferon, alpha 13 2.2436
FGF6 fibroblast growth factor 6 2.24255
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3 2.2421
COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) 2.2398
KLK14 kallikrein-related peptidase 14 2.23965
MCTP2 multiple C2 domains, transmembrane 2 2.23805
LUZP4 leucine zipper protein 4 2.2355
CETP cholesteryl ester transfer protein, plasma 2.23475
ADAM18 ADAM metallopeptidase domain 18 2.2308
STAP2 signal transducing adaptor family member 2 2.23035
SKAP1 src kinase associated phosphoprotein 1 2.22745
KAT6A K(lysine) acetyltransferase 6A 2.22655
BSG basigin (Ok blood group) 2.22415
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1 2.2238
DENND2D DENN/MADD domain containing 2D 2.2232
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 2.22305
RNLS renalase, FAD-dependent amine oxidase 2.2224
HPSE2 heparanase 2 (inactive) 2.2222
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa 2.22195
DCHS2 dachsous cadherin-related 2 2.2132
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae) 2.21205
YBX2 Y box binding protein 2 2.20995
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 2.2083
RBPJ recombination signal binding protein for immunoglobulin kappa J region 2.20757
OR7E24 olfactory receptor, family 7, subfamily E, member 24 2.20755
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 2.2062
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 2.2041
FIP1L1 factor interacting with PAPOLA and CPSF1 2.20385
TYRO3 TYRO3 protein tyrosine kinase 2.20333
AAAS achalasia, adrenocortical insufficiency, alacrimia 2.2028
INTS6 integrator complex subunit 6 2.20233
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 2.20033
USP19 ubiquitin specific peptidase 19 2.1965
NME8 NME/NM23 family member 8 2.1959
MEF2C myocyte enhancer factor 2C 2.19358
NR1H2 nuclear receptor subfamily 1, group H, member 2 2.1933
FAM171A1 family with sequence similarity 171, member A1 2.192
IL2RG interleukin 2 receptor, gamma 2.1895
IL2 interleukin 2 2.1887
WIZ widely interspaced zinc finger motifs 2.18808
OVGP1 oviductal glycoprotein 1, 120kDa 2.18715
HAS2 hyaluronan synthase 2 2.1867
STN1 STN1 subunit of CST complex 2.1857
EIF4EBP3 eukaryotic translation initiation factor 4E binding protein 3 2.185
NCBP2 nuclear cap binding protein subunit 2, 20kDa 2.18252
RPL10L ribosomal protein L10-like 2.18035
WNT5B wingless-type MMTV integration site family, member 5B 2.1799
TEC tec protein tyrosine kinase 2.17935
RPS5 ribosomal protein S5 2.1793
ADRB1 adrenoceptor beta 1 2.179
SPTLC3 serine palmitoyltransferase, long chain base subunit 3 2.17835
FAM124B family with sequence similarity 124B 2.17705
EPN3 epsin 3 2.17655
DPT dermatopontin 2.17637
FCAR Fc fragment of IgA receptor 2.175
SLC22A14 solute carrier family 22, member 14 2.17475
ZNF460 zinc finger protein 460 2.17135
RAD50 RAD50 homolog (S. cerevisiae) 2.1705
F8A2 coagulation factor VIII-associated 2 2.1703
MYH13 myosin, heavy chain 13, skeletal muscle 2.16985
DRC11 dynein regulatory complex subunit 11 2.1696
NOTCH1 notch 1 2.16875
RBBP7 retinoblastoma binding protein 7 2.1677
NSDHL NAD(P) dependent steroid dehydrogenase-like 2.16685
CXCR6 chemokine (C-X-C motif) receptor 6 2.16677
CROCC ciliary rootlet coiled-coil, rootletin 2.16595
CCL21 chemokine (C-C motif) ligand 21 2.16315
STAMBP STAM binding protein 2.1629
VTI1B vesicle transport through interaction with t-SNAREs 1B 2.1612
SPEF1 sperm flagellar 1 2.1611
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 2.16085
PPIL6 peptidylprolyl isomerase (cyclophilin)-like 6 2.1608
RCN3 reticulocalbin 3, EF-hand calcium binding domain 2.16073
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 2.1605
FAM107A family with sequence similarity 107, member A 2.16022
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 2.15903
CHN1 chimerin 1 2.1566
DAZL deleted in azoospermia-like 2.155
FOXC2 forkhead box C2 2.15465
MNAT1 MNAT CDK-activating kinase assembly factor 1 2.1525
EMX1 empty spiracles homeobox 1 2.1507
SPMAP2 sperm microtubule associated protein 2 2.1503
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 2.14875
IL18RAP interleukin 18 receptor accessory protein 2.1482
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 2.1464
ERN1 endoplasmic reticulum to nucleus signaling 1 2.13975
CPNE7 copine VII 2.13755
BEST1 bestrophin 1 2.13705
WIPF1 WAS/WASL interacting protein family, member 1 2.1365
MAGEA6 melanoma antigen family A6 2.1363
ZCCHC14 zinc finger, CCHC domain containing 14 2.13597
PARP11 poly (ADP-ribose) polymerase family, member 11 2.13285
PAPPA pregnancy-associated plasma protein A, pappalysin 1 2.1324
LPAR1 lysophosphatidic acid receptor 1 2.13148
CXCL12 chemokine (C-X-C motif) ligand 12 2.13138
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 2.13095
STON1-GTF2A1L STON1-GTF2A1L readthrough 2.12955
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 2.1286
PRR14L proline rich 14-like 2.1269
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 2.12605
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 2.12585
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 2.12543
CXCR4 chemokine (C-X-C motif) receptor 4 2.12522
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 2.12385
MRPS17 mitochondrial ribosomal protein S17 2.1211
AK5 adenylate kinase 5 2.12035
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 2.11735
CALCOCO2 calcium binding and coiled-coil domain 2 2.1136
KCNIP2 Kv channel interacting protein 2 2.113
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 2.1127
TBPL1 TBP-like 1 2.1115
LIPE lipase, hormone-sensitive 2.10997
INO80D INO80 complex subunit D 2.1097
IHH indian hedgehog 2.10795
TEX11 testis expressed 11 2.10765
SAA2 serum amyloid A2 2.10695
ADAM20 ADAM metallopeptidase domain 20 2.10485
PSORS1C2 psoriasis susceptibility 1 candidate 2 2.1046
GOLT1B golgi transport 1B 2.10455
DOC2A double C2-like domains, alpha 2.10425
LCE2B late cornified envelope 2B 2.10345
TRAPPC8 trafficking protein particle complex 8 2.1028
ARHGAP4 Rho GTPase activating protein 4 2.10225
DNM1 dynamin 1 2.1003
MUC1 mucin 1, cell surface associated 2.0989
ZMYND8 zinc finger, MYND-type containing 8 2.09811
PTGER4 prostaglandin E receptor 4 (subtype EP4) 2.0981
CCDC87 coiled-coil domain containing 87 2.0928
BPI bactericidal/permeability-increasing protein 2.09165
IPCEF1 interaction protein for cytohesin exchange factors 1 2.0914
STX12 syntaxin 12 2.09013
EN1 engrailed homeobox 1 2.08895
NLRP2B NLR family pyrin domain containing 2B 2.0886
PRRX2 paired related homeobox 2 2.0878
DEFA3 defensin, alpha 3, neutrophil-specific 2.08775
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 2.08765
MACROH2A2 macroH2A.2 histone 2.08765
EXOC1 exocyst complex component 1 2.08685
RIC8A RIC8 guanine nucleotide exchange factor A 2.0862
FKBP8 FK506 binding protein 8, 38kDa 2.08553
BMX BMX non-receptor tyrosine kinase 2.0832
ECHDC1 ethylmalonyl-CoA decarboxylase 1 2.0827
ARL4A ADP-ribosylation factor-like 4A 2.08225
DNAH3 dynein, axonemal, heavy chain 3 2.0815
EDC4 enhancer of mRNA decapping 4 2.08125
PPCS phosphopantothenoylcysteine synthetase 2.0812
ATG3 autophagy related 3 2.08068
TSPYL5 TSPY-like 5 2.0794
TRIP12 thyroid hormone receptor interactor 12 2.0792
APOBEC3A_B APOBEC3A and APOBEC3B deletion hybrid 2.07857
INSL5 insulin-like 5 2.07785
EIF4A3 eukaryotic translation initiation factor 4A3 2.07565
TET3 tet methylcytosine dioxygenase 3 2.074
ANKRD12 ankyrin repeat domain 12 2.07258
LRRC15 leucine rich repeat containing 15 2.06975
PLPP1 phospholipid phosphatase 1 2.06695
CCDC88C coiled-coil domain containing 88C 2.0654
UGP2 UDP-glucose pyrophosphorylase 2 2.0635
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 2.0631
RBMXL2 RNA binding motif protein, X-linked-like 2 2.06305
PKNOX1 PBX/knotted 1 homeobox 1 2.0621
BTN3A1 butyrophilin, subfamily 3, member A1 2.06205
PLIN1 perilipin 1 2.06095
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 2.06078
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 2.0599
SIRPG signal-regulatory protein gamma 2.0594
PZP pregnancy-zone protein 2.0579
ZNF778 zinc finger protein 778 2.05705
STUM stum, mechanosensory transduction mediator homolog 2.05685
RSPH6A radial spoke head 6 homolog A (Chlamydomonas) 2.0561
SF3A1 splicing factor 3a, subunit 1, 120kDa 2.05607
PSKH1 protein serine kinase H1 2.05395
TMEM126B transmembrane protein 126B 2.0528
TASL TLR adaptor interacting with endolysosomal SLC15A4 2.0523
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 2.05217
DNAH7 dynein, axonemal, heavy chain 7 2.0512
KAT7 K(lysine) acetyltransferase 7 2.04975
SH3TC2 SH3 domain and tetratricopeptide repeats 2 2.04965
TMPRSS3 transmembrane protease, serine 3 2.0493
MNT MAX network transcriptional repressor 2.0472
CCNK cyclin K 2.047
AP3M2 adaptor-related protein complex 3, mu 2 subunit 2.04355
BAG4 BCL2-associated athanogene 4 2.0425
ZNF79 zinc finger protein 79 2.0421
CMKLR1 chemerin chemokine-like receptor 1 2.04135
SNCA synuclein, alpha (non A4 component of amyloid precursor) 2.03744
CD33 CD33 molecule 2.03725
TROAP trophinin associated protein 2.03615
ADGRG3 adhesion G protein-coupled receptor G3 2.03445
ZNF557 zinc finger protein 557 2.0328
SOD2 superoxide dismutase 2, mitochondrial 2.03269
TXNIP thioredoxin interacting protein 2.03203
STX1A syntaxin 1A (brain) 2.0316
CKS2 CDC28 protein kinase regulatory subunit 2 2.02945
PIWIL1 piwi-like RNA-mediated gene silencing 1 2.02795
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 2.0272
ACOXL acyl-CoA oxidase-like 2.0267
CNN1 calponin 1, basic, smooth muscle 2.02565
NKG7 natural killer cell granule protein 7 2.02455
CDX4 caudal type homeobox 4 2.0245
AIRE autoimmune regulator 2.0237
ZNF574 zinc finger protein 574 2.023
CRTC1 CREB regulated transcription coactivator 1 2.01825
RFX2 regulatory factor X, 2 (influences HLA class II expression) 2.01775
CIAO3 cytosolic iron-sulfur assembly component 3 2.0174
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) 2.01725
UTF1 undifferentiated embryonic cell transcription factor 1 2.0164
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 2.01565
CERT1 ceramide transporter 1 2.01555
VASH2 vasohibin 2 2.01495
GML glycosylphosphatidylinositol anchored molecule like 2.0143
CHAMP1 chromosome alignment maintaining phosphoprotein 1 2.0137
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 2.013
MAST4 microtubule associated serine/threonine kinase family member 4 2.01297
IL36RN interleukin 36 receptor antagonist 2.01125
NSUN3 NOP2/Sun domain family, member 3 2.01095
ZNF208 zinc finger protein 208 2.0105
CCNA1 cyclin A1 2.00755
ERMAP erythroblast membrane-associated protein (Scianna blood group) 2.00655
FOXC1 forkhead box C1 2.0061
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa 2.00518
LEP leptin 2.00195
NPTXR neuronal pentraxin receptor 2.00155
WIPF2 WAS/WASL interacting protein family, member 2 2.00132

decreased expression

Symbol Name Standardized Value
TRIB3 tribbles pseudokinase 3 -10.0
TM9SF3 transmembrane 9 superfamily member 3 -8.2209
GDF15 growth differentiation factor 15 -7.8956
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -7.3047
ZW10 zw10 kinetochore protein -6.1368
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -5.81595
PMM2 phosphomannomutase 2 -5.66055
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -5.50685
LSR lipolysis stimulated lipoprotein receptor -5.33785
NUP93 nucleoporin 93kDa -5.319
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -5.28985
RFC2 replication factor C (activator 1) 2, 40kDa -5.26995
RAI14 retinoic acid induced 14 -5.2338
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -5.21765
HACD3 3-hydroxyacyl-CoA dehydratase 3 -5.20145
MELK maternal embryonic leucine zipper kinase -5.10495
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -5.0453
UBE3C ubiquitin protein ligase E3C -5.03325
ISOC1 isochorismatase domain containing 1 -5.02875
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -5.02015
DERA deoxyribose-phosphate aldolase (putative) -5.01005
FABP5 fatty acid binding protein 5 (psoriasis-associated) -5.0
ACLY ATP citrate lyase -4.93902
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -4.89215
CORO1A coronin, actin binding protein, 1A -4.87905
TMED7 transmembrane emp24 protein transport domain containing 7 -4.8612
ARID5B AT rich interactive domain 5B (MRF1-like) -4.8339
ZNF586 zinc finger protein 586 -4.8323
PHKA1 phosphorylase kinase, alpha 1 (muscle) -4.79485
PCCB propionyl CoA carboxylase, beta polypeptide -4.78855
NT5DC2 5'-nucleotidase domain containing 2 -4.78375
USP6NL USP6 N-terminal like -4.71205
RUVBL1 RuvB-like AAA ATPase 1 -4.6782
UGDH UDP-glucose 6-dehydrogenase -4.66275
BZW2 basic leucine zipper and W2 domains 2 -4.52785
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -4.50045
GNAS GNAS complex locus -4.48877
PECR peroxisomal trans-2-enoyl-CoA reductase -4.484
COG2 component of oligomeric golgi complex 2 -4.46725
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -4.4516
PIH1D1 PIH1 domain containing 1 -4.4291
CDC25B cell division cycle 25B -4.4237
CIAPIN1 cytokine induced apoptosis inhibitor 1 -4.4084
CHEK1 checkpoint kinase 1 -4.38835
CERK ceramide kinase -4.38535
FGFR4 fibroblast growth factor receptor 4 -4.36538
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) -4.2659
HOXA5 homeobox A5 -4.25025
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -4.22268
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -4.1647
ANKRD10 ankyrin repeat domain 10 -4.1503
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -4.1471
TOR1A torsin family 1, member A (torsin A) -4.13625
TCTA T-cell leukemia translocation altered -4.082
MKNK1 MAP kinase interacting serine/threonine kinase 1 -4.07045
CD58 CD58 molecule -4.02207
NKAPD1 NKAP domain containing 1 -4.0023
PLS1 plastin 1 -3.98015
HMG20B high mobility group 20B -3.9723
CGRRF1 cell growth regulator with ring finger domain 1 -3.8911
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -3.8851
PEG10 paternally expressed 10 -3.86535
DOLPP1 dolichyldiphosphatase 1 -3.8483
DYNLT3 dynein, light chain, Tctex-type 3 -3.7903
CDC45 cell division cycle 45 -3.76165
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 -3.7593
TDG thymine-DNA glycosylase -3.71175
GRHPR glyoxylate reductase/hydroxypyruvate reductase -3.69437
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.6869
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 -3.65755
CCP110 centriolar coiled coil protein 110kDa -3.60935
REG1B regenerating islet-derived 1 beta -3.58495
SPON2 spondin 2, extracellular matrix protein -3.5657
RNPS1 RNA binding protein S1, serine-rich domain -3.49108
ARID4B AT rich interactive domain 4B (RBP1-like) -3.4716
ASNS asparagine synthetase (glutamine-hydrolyzing) -3.46365
ZWILCH zwilch kinetochore protein -3.39355
PARP2 poly (ADP-ribose) polymerase 2 -3.38573
SNX4 sorting nexin 4 -3.37063
TES testin LIM domain protein -3.36287
RAB21 RAB21, member RAS oncogene family -3.35785
HSPA1A heat shock 70kDa protein 1A -3.35285
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase -3.35135
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 -3.35075
DHRS7 dehydrogenase/reductase (SDR family) member 7 -3.3498
BMP4 bone morphogenetic protein 4 -3.34805
BIRC2 baculoviral IAP repeat containing 2 -3.3442
REEP5 receptor accessory protein 5 -3.26795
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -3.2666
CHMP1A charged multivesicular body protein 1A -3.2633
PUM3 pumilio RNA binding family member 3 -3.2571
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -3.23852
ACBD3 acyl-CoA binding domain containing 3 -3.20353
CRY1 cryptochrome circadian clock 1 -3.20295
SYNGR2 synaptogyrin 2 -3.17455
NRIP1 nuclear receptor interacting protein 1 -3.15902
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A -3.1516
MAP2K5 mitogen-activated protein kinase kinase 5 -3.14512
ERBB2 erb-b2 receptor tyrosine kinase 2 -3.1351
TCEAL9 transcription elongation factor A like 9 -3.12605
DUSP3 dual specificity phosphatase 3 -3.12587
CCNA2 cyclin A2 -3.12383
DCK deoxycytidine kinase -3.09465
TXNL4B thioredoxin-like 4B -3.08175
HEBP1 heme binding protein 1 -3.0747
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase -3.0559
ELL3 elongation factor RNA polymerase II-like 3 -3.05153
ZHX2 zinc fingers and homeoboxes 2 -3.0476
ZCCHC8 zinc finger, CCHC domain containing 8 -3.03115
TMEM267 transmembrane protein 267 -3.02855
ABHD4 abhydrolase domain containing 4 -3.01435
CUL5 cullin 5 -3.00908
SNRPF small nuclear ribonucleoprotein polypeptide F -3.00715
TLK2 tousled-like kinase 2 -3.00418
CLTB clathrin, light chain B -2.97531
DEK DEK proto-oncogene -2.9664
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 -2.95285
MVD mevalonate (diphospho) decarboxylase -2.9442
PWP1 PWP1 homolog (S. cerevisiae) -2.94418
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 -2.91505
POLR3B polymerase (RNA) III (DNA directed) polypeptide B -2.9084
TRABD TraB domain containing -2.9055
ANXA5 annexin A5 -2.8903
FUBP3 far upstream element (FUSE) binding protein 3 -2.88865
TAGLN2 transgelin 2 -2.8873
SCYL2 SCY1-like 2 (S. cerevisiae) -2.88475
GOLPH3 golgi phosphoprotein 3 (coat-protein) -2.8749
RFC5 replication factor C (activator 1) 5, 36.5kDa -2.87218
ADAM10 ADAM metallopeptidase domain 10 -2.84347
CNIH1 cornichon family AMPA receptor auxiliary protein 1 -2.84235
CDO1 cysteine dioxygenase type 1 -2.82925
DLAT dihydrolipoamide S-acetyltransferase -2.82698
REG3A regenerating islet-derived 3 alpha -2.82315
MTTP microsomal triglyceride transfer protein -2.81735
MCUB mitochondrial calcium uniporter dominant negative subunit beta -2.8167
BEX3 brain expressed X-linked 3 -2.8144
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 -2.809
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.80205
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -2.8001
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -2.7896
NCKAP1 NCK-associated protein 1 -2.7862
CHUK conserved helix-loop-helix ubiquitous kinase -2.76685
NFRKB nuclear factor related to kappaB binding protein -2.76535
TPD52L2 tumor protein D52-like 2 -2.76195
PTS 6-pyruvoyltetrahydropterin synthase -2.7512
SH3TC1 SH3 domain and tetratricopeptide repeats 1 -2.7484
PGAP3 post-GPI attachment to proteins 3 -2.7461
NPDC1 neural proliferation, differentiation and control, 1 -2.7456
FDX1 ferredoxin 1 -2.74315
SMN2 survival of motor neuron 2, centromeric -2.7416
TENM1 teneurin transmembrane protein 1 -2.73485
BBS4 Bardet-Biedl syndrome 4 -2.73228
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.72435
FOXF2 forkhead box F2 -2.71445
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -2.71397
TMED2 transmembrane emp24 domain trafficking protein 2 -2.71378
PCNA proliferating cell nuclear antigen -2.70645
WWC2 WW and C2 domain containing 2 -2.68905
EPB41L3 erythrocyte membrane protein band 4.1-like 3 -2.68362
TEX10 testis expressed 10 -2.6824
ZFC3H1 zinc finger, C3H1-type containing -2.6823
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 -2.6813
CAAP1 caspase activity and apoptosis inhibitor 1 -2.67865
SLC39A1 solute carrier family 39 (zinc transporter), member 1 -2.6756
DKK3 dickkopf WNT signaling pathway inhibitor 3 -2.67013
TUBGCP5 tubulin, gamma complex associated protein 5 -2.66355
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -2.65535
SLC16A4 solute carrier family 16, member 4 -2.65225
S100A10 S100 calcium binding protein A10 -2.6516
MINPP1 multiple inositol-polyphosphate phosphatase 1 -2.6462
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -2.6436
PSAT1 phosphoserine aminotransferase 1 -2.6407
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase -2.63975
FZD2 frizzled class receptor 2 -2.63505
REG1A regenerating islet-derived 1 alpha -2.63495
UFM1 ubiquitin-fold modifier 1 -2.63275
SLC75A1 solute carrier family 75 member 1 -2.6266
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.62063
CENPE centromere protein E, 312kDa -2.61625
SGPP1 sphingosine-1-phosphate phosphatase 1 -2.61465
DEFA5 defensin, alpha 5, Paneth cell-specific -2.5973
PTK2 protein tyrosine kinase 2 -2.59055
ATF4 activating transcription factor 4 -2.587
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein -2.58095
RTN4 reticulon 4 -2.57905
BFAR bifunctional apoptosis regulator -2.5782
H1-0 H1.0 linker histone -2.56735
UBA5 ubiquitin-like modifier activating enzyme 5 -2.56175
UBE2J1 ubiquitin-conjugating enzyme E2, J1 -2.56091
DEFA6 defensin, alpha 6, Paneth cell-specific -2.55035
PDZD2 PDZ domain containing 2 -2.54573
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) -2.5354
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.52762
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 -2.5255
MTA1 metastasis associated 1 -2.52192
MTMR12 myotubularin related protein 12 -2.51585
ADSL adenylosuccinate lyase -2.50812
RMDN1 regulator of microtubule dynamics 1 -2.50745
HEATR3 HEAT repeat containing 3 -2.50345
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa -2.49985
RGS2 regulator of G-protein signaling 2 -2.48555
DDA1 DET1 and DDB1 associated 1 -2.4756
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 -2.47315
ASGR2 asialoglycoprotein receptor 2 -2.46885
CNKSR3 CNKSR family member 3 -2.46425
FERRY3 FERRY endosomal RAB5 effector complex subunit 3 -2.46225
SH3GLB2 SH3-domain GRB2-like endophilin B2 -2.46135
PTPRE protein tyrosine phosphatase, receptor type, E -2.45855
NUP42 nucleoporin 42 -2.45315
PERP PERP, TP53 apoptosis effector -2.45145
EXOC5 exocyst complex component 5 -2.4398
TTC38 tetratricopeptide repeat domain 38 -2.4337
MSANTD3-TMEFF1 MSANTD3-TMEFF1 readthrough -2.4242
MSANTD2 Myb/SANT-like DNA-binding domain containing 2 -2.41655
PNPO pyridoxamine 5'-phosphate oxidase -2.407
BRIX1 BRX1, biogenesis of ribosomes -2.4024
RNF5 ring finger protein 5, E3 ubiquitin protein ligase -2.3983
TSPAN12 tetraspanin 12 -2.39475
DENND5B DENN/MADD domain containing 5B -2.38955
TBX3 T-box 3 -2.38655
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa -2.3739
TMEM176B transmembrane protein 176B -2.3704
SOAT2 sterol O-acyltransferase 2 -2.36808
PPIC peptidylprolyl isomerase C (cyclophilin C) -2.3657
PAWR PRKC, apoptosis, WT1, regulator -2.36112
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) -2.36055
SNRPA small nuclear ribonucleoprotein polypeptide A -2.35655
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae) -2.35635
TMSB15C thymosin beta 15C -2.35445
LRRC8D leucine rich repeat containing 8 family, member D -2.35285
ECT2 epithelial cell transforming 2 -2.35255
CNPY3 canopy FGF signaling regulator 3 -2.3515
CA5A carbonic anhydrase VA, mitochondrial -2.342
HHEX hematopoietically expressed homeobox -2.34165
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) -2.33905
DNAAF2 dynein, axonemal, assembly factor 2 -2.33475
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.33435
CLCN6 chloride channel, voltage-sensitive 6 -2.33155
SPRING1 SREBF pathway regulator in golgi 1 -2.32925
ORAI3 ORAI calcium release-activated calcium modulator 3 -2.32835
URM1 ubiquitin related modifier 1 -2.3173
COPS7A COP9 signalosome subunit 7A -2.31545
ADGRG1 adhesion G protein-coupled receptor G1 -2.3121
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -2.3099
KCTD3 potassium channel tetramerization domain containing 3 -2.30745
SRSF9 serine/arginine-rich splicing factor 9 -2.30542
MTERF3 mitochondrial transcription termination factor 3 -2.3045
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 -2.29705
KXD1 KxDL motif containing 1 -2.29315
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -2.28947
ELOVL2 ELOVL fatty acid elongase 2 -2.287
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa -2.28365
SPA17 sperm autoantigenic protein 17 -2.2836
PIGH phosphatidylinositol glycan anchor biosynthesis, class H -2.2831
MATCAP2 microtubule associated tyrosine carboxypeptidase 2 -2.28015
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 -2.28
S100A14 S100 calcium binding protein A14 -2.27795
CPE carboxypeptidase E -2.27708
NOP2 NOP2 nucleolar protein -2.2733
PRMT3 protein arginine methyltransferase 3 -2.27325
RFC3 replication factor C (activator 1) 3, 38kDa -2.27277
LRRC40 leucine rich repeat containing 40 -2.2648
UBAC1 UBA domain containing 1 -2.26035
SDHAF3 succinate dehydrogenase complex assembly factor 3 -2.2594
EXT1 exostosin glycosyltransferase 1 -2.25505
GARS1 glycyl-tRNA synthetase 1 -2.25385
MSMO1 methylsterol monooxygenase 1 -2.2442
CREG1 cellular repressor of E1A-stimulated genes 1 -2.2415
MOGS mannosyl-oligosaccharide glucosidase -2.24035
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1 -2.23743
ERH enhancer of rudimentary homolog (Drosophila) -2.2358
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) -2.2339
TMEM176A transmembrane protein 176A -2.22845
EIF2D eukaryotic translation initiation factor 2D -2.2263
DNM3 dynamin 3 -2.2257
LOC128125822 uncharacterized LOC128125822 -2.22543
KRT8 keratin 8, type II -2.22495
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 -2.22407
RWDD3 RWD domain containing 3 -2.22235
TSPAN6 tetraspanin 6 -2.22095
RAB26 RAB26, member RAS oncogene family -2.21917
GCN1 GCN1 activator of EIF2AK4 -2.2187
ZNF668 zinc finger protein 668 -2.21755
TAC1 tachykinin, precursor 1 -2.21395
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa -2.21318
PAIP1 poly(A) binding protein interacting protein 1 -2.21286
GRAMD4 GRAM domain containing 4 -2.20775
TM6SF1 transmembrane 6 superfamily member 1 -2.20775
RAB4B RAB4B, member RAS oncogene family -2.20695
NRSN2 neurensin 2 -2.20435
CAMK1 calcium/calmodulin-dependent protein kinase I -2.2025
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26 -2.2023
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa -2.2001
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase -2.196
DCTN4 dynactin 4 (p62) -2.1923
PLAC1 placenta-specific 1 -2.1892
CCDC15 coiled-coil domain containing 15 -2.1839
TM4SF1 transmembrane 4 L six family member 1 -2.1812
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 -2.18095
CAMTA1 calmodulin binding transcription activator 1 -2.18015
LYZ lysozyme -2.1786
ZNF140 zinc finger protein 140 -2.1756
RDX radixin -2.17512
STK16 serine/threonine kinase 16 -2.17275
APOM apolipoprotein M -2.16983
MBIP MAP3K12 binding inhibitory protein 1 -2.1685
GATA6 GATA binding protein 6 -2.1674
SCD stearoyl-CoA desaturase (delta-9-desaturase) -2.16333
EIF4H eukaryotic translation initiation factor 4H -2.1605
PXMP2 peroxisomal membrane protein 2, 22kDa -2.15895
F2R coagulation factor II (thrombin) receptor -2.15795
RHBDF1 rhomboid 5 homolog 1 (Drosophila) -2.1543
ASDURF ASNSD1 upstream open reading frame -2.15415
RAB5C RAB5C, member RAS oncogene family -2.15385
HPRT1 hypoxanthine phosphoribosyltransferase 1 -2.15345
E2F5 E2F transcription factor 5, p130-binding -2.15315
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) -2.14995
UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3 -2.14855
APLP2 amyloid beta (A4) precursor-like protein 2 -2.14697
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 -2.1449
IVD isovaleryl-CoA dehydrogenase -2.14013
DTYMK deoxythymidylate kinase (thymidylate kinase) -2.1393
IL13RA1 interleukin 13 receptor, alpha 1 -2.13546
RNASE4 ribonuclease, RNase A family, 4 -2.12853
PTPN3 protein tyrosine phosphatase, non-receptor type 3 -2.12815
IDH3B isocitrate dehydrogenase 3 (NAD+) beta -2.1272
ETNK2 ethanolamine kinase 2 -2.1267
GPS1 G protein pathway suppressor 1 -2.1242
ROGDI rogdi homolog (Drosophila) -2.12185
BAG3 BCL2-associated athanogene 3 -2.12025
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -2.11595
PON2 paraoxonase 2 -2.11558
TMEM123 transmembrane protein 123 -2.11435
MBL2 mannose-binding lectin (protein C) 2, soluble -2.11245
PUS3 pseudouridylate synthase 3 -2.1095
MCRS1 microspherule protein 1 -2.10295
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase -2.09755
MRPL46 mitochondrial ribosomal protein L46 -2.0942
CREB1 cAMP responsive element binding protein 1 -2.09313
SPAG16 sperm associated antigen 16 -2.0927
RWDD2A RWD domain containing 2A -2.09265
GREB1L growth regulation by estrogen in breast cancer-like -2.09015
SHOC2 soc-2 suppressor of clear homolog (C. elegans) -2.08945
PIGB phosphatidylinositol glycan anchor biosynthesis, class B -2.0876
CASD1 CAS1 domain containing 1 -2.08705
ASGR1 asialoglycoprotein receptor 1 -2.08625
RNFT1-DT RNFT1 divergent transcript -2.08415
BABAM1 BRISC and BRCA1 A complex member 1 -2.07945
NECAP1 NECAP endocytosis associated 1 -2.07885
XPOT exportin, tRNA -2.07665
MYZAP myocardial zonula adherens protein -2.07538
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 -2.0737
ADAP2 ArfGAP with dual PH domains 2 -2.07305
METTL22 methyltransferase like 22 -2.07015
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -2.0583
OSGEP O-sialoglycoprotein endopeptidase -2.05725
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 -2.0572
PDIA4 protein disulfide isomerase family A, member 4 -2.04942
ARHGAP5 Rho GTPase activating protein 5 -2.04865
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 -2.048
ATF5 activating transcription factor 5 -2.04475
NANS N-acetylneuraminic acid synthase -2.04295
CEBPD CCAAT/enhancer binding protein (C/EBP), delta -2.04155
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -2.0412
SCHIP1 schwannomin interacting protein 1 -2.0412
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 -2.03685
BPHL biphenyl hydrolase-like (serine hydrolase) -2.0328
EMC9 ER membrane protein complex subunit 9 -2.03185
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 -2.0303
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 -2.02895
UGT2B10 UDP glucuronosyltransferase 2 family, polypeptide B10 -2.0251
LMO2 LIM domain only 2 (rhombotin-like 1) -2.02365
STXBP2 syntaxin binding protein 2 -2.0222
FSTL1 follistatin-like 1 -2.02185
QSOX1 quiescin Q6 sulfhydryl oxidase 1 -2.01945
BCOR BCL6 corepressor -2.0186
STARD3 StAR-related lipid transfer (START) domain containing 3 -2.0132
PAX6 paired box 6 -2.01015
HABP2 hyaluronan binding protein 2 -2.00835
TMSB15B thymosin beta 15B -2.0076
SLC25A46 solute carrier family 25, member 46 -2.00475
SHMT1 serine hydroxymethyltransferase 1 (soluble) -2.00155