CRCGN011_HEPG2_24H:J14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

54 genes differentially expressed following the CRCGN011_HEPG2_24H:J14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 6.06785
GPATCH8 G patch domain containing 8 5.43297
PPARG peroxisome proliferator-activated receptor gamma 5.23265
E2F2 E2F transcription factor 2 5.0206
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 5.0097
PRR15L proline rich 15-like 4.5738
ABHD6 abhydrolase domain containing 6 3.55438
NMU neuromedin U 3.31275
PFKL phosphofructokinase, liver 3.17402
RXYLT1 ribitol xylosyltransferase 1 3.16048
PLSCR3 phospholipid scramblase 3 2.90707
SSBP2 single-stranded DNA binding protein 2 2.8643
CCNF cyclin F 2.85122
PCDHB11 protocadherin beta 11 2.82512
TESK1 testis-specific kinase 1 2.7222
LCN2 lipocalin 2 2.557
MGAM maltase-glucoamylase 2.40785
CTSD cathepsin D 2.40725
GOLT1B golgi transport 1B 2.36745
KLHL9 kelch-like family member 9 2.31527
SELENOW selenoprotein W 2.281
NME2 NME/NM23 nucleoside diphosphate kinase 2 2.27225
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.25655
TZMP1 transition zone microprotein 1 2.25367
BCL7C B-cell CLL/lymphoma 7C 2.22225
GUK1 guanylate kinase 1 2.21975
H1-10 H1.10 linker histone 2.2151
RAB21 RAB21, member RAS oncogene family 2.19395
CYCS cytochrome c, somatic 2.1765
RAI14 retinoic acid induced 14 2.1365
TMSB4X thymosin beta 4, X-linked 2.11445
ANXA1 annexin A1 2.0354

decreased expression

Symbol Name Standardized Value
HEATR1 HEAT repeat containing 1 -6.07885
CD320 CD320 molecule -5.2506
LDHD lactate dehydrogenase D -4.691
CCDC86 coiled-coil domain containing 86 -4.6398
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -3.9658
GNAS GNAS complex locus -3.78051
OXA1L oxidase (cytochrome c) assembly 1-like -3.76905
PCNA proliferating cell nuclear antigen -3.6739
EIF5 eukaryotic translation initiation factor 5 -3.66285
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.4242
CHEK1 checkpoint kinase 1 -3.18907
DSG2 desmoglein 2 -2.89115
AZGP1 alpha-2-glycoprotein 1, zinc-binding -2.74653
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.6505
SLC35F2 solute carrier family 35, member F2 -2.48235
HLA-DMA major histocompatibility complex, class II, DM alpha -2.35845
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -2.35493
C1RL complement component 1, r subcomponent-like -2.3279
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 -2.2988
IL13RA2 interleukin 13 receptor, alpha 2 -2.275
FOS FBJ murine osteosarcoma viral oncogene homolog -2.0872
NAT10 N-acetyltransferase 10 (GCN5-related) -2.00915