| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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62 genes differentially expressed following the CRCGN011_HEPG2_24H:J15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 8.05425 |
| NOTCH1 | notch 1 | 5.21405 |
| MYLK | myosin light chain kinase | 4.8039 |
| ADRB2 | adrenoceptor beta 2, surface | 4.62465 |
| CHN1 | chimerin 1 | 4.2112 |
| SSBP2 | single-stranded DNA binding protein 2 | 3.8006 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.74055 |
| EVL | Enah/Vasp-like | 3.57575 |
| MAP7 | microtubule-associated protein 7 | 3.42025 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 3.2307 |
| ABHD6 | abhydrolase domain containing 6 | 3.20415 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 3.14325 |
| EPN2 | epsin 2 | 3.07668 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.9025 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 2.8099 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.75003 |
| GPATCH8 | G patch domain containing 8 | 2.74007 |
| TEX10 | testis expressed 10 | 2.7264 |
| GPC1 | glypican 1 | 2.71922 |
| CNPY3 | canopy FGF signaling regulator 3 | 2.5757 |
| CCNF | cyclin F | 2.54853 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.44645 |
| SDAD1 | SDA1 domain containing 1 | 2.34835 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 | 2.34347 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 2.3418 |
| HOOK2 | hook microtubule-tethering protein 2 | 2.2469 |
| SSBP1 | single-stranded DNA binding protein 1, mitochondrial | 2.1642 |
| NUP93 | nucleoporin 93kDa | 2.15545 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | 2.1408 |
| EPHA3 | EPH receptor A3 | 2.13475 |
| RPL8 | ribosomal protein L8 | 2.124 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 | 2.05755 |
| FAH | fumarylacetoacetate hydrolase (fumarylacetoacetase) | 2.0322 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 2.0015 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -8.57475 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -5.45435 |
| TUBB6 | tubulin, beta 6 class V | -5.3233 |
| PCNA | proliferating cell nuclear antigen | -4.70415 |
| GOLT1B | golgi transport 1B | -4.62835 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.43985 |
| HMG20B | high mobility group 20B | -4.28018 |
| ADI1 | acireductone dioxygenase 1 | -3.96295 |
| DERA | deoxyribose-phosphate aldolase (putative) | -3.9237 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.65285 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.3558 |
| SNX11 | sorting nexin 11 | -2.80365 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.73517 |
| TBC1D31 | TBC1 domain family, member 31 | -2.6096 |
| VDAC1 | voltage-dependent anion channel 1 | -2.5197 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.41418 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.39392 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.13065 |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 | -2.11595 |
| NMRK2 | nicotinamide riboside kinase 2 | -2.10155 |
| APIP | APAF1 interacting protein | -2.07885 |
| FCRLB | Fc receptor-like B | -2.07665 |
| RTL8C | retrotransposon Gag like 8C | -2.07495 |
| PGM1 | phosphoglucomutase 1 | -2.0718 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -2.06435 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -2.04135 |
| KCNJ1 | potassium channel, inwardly rectifying subfamily J, member 1 | -2.00462 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.00305 |
