CRCGN011_HEPG2_24H:J17 Gene Set
Genes
39 genes differentially expressed following the CRCGN011_HEPG2_24H:J17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CYCS
|
cytochrome c, somatic
|
5.31095
|
|
UBQLN2
|
ubiquilin 2
|
4.84535
|
|
RRAGA
|
Ras-related GTP binding A
|
3.86085
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
3.33305
|
|
CGRRF1
|
cell growth regulator with ring finger domain 1
|
3.2596
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.25675
|
|
MICALL1
|
MICAL-like 1
|
3.21648
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
3.00417
|
|
POLR2K
|
polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
|
2.73587
|
|
GOLT1B
|
golgi transport 1B
|
2.3322
|
|
ILK
|
integrin-linked kinase
|
2.32665
|
|
ZBTB5
|
zinc finger and BTB domain containing 5
|
2.21805
|
|
SNX17
|
sorting nexin 17
|
2.21325
|
|
TLR4
|
toll-like receptor 4
|
2.19605
|
|
PGK1
|
phosphoglycerate kinase 1
|
2.19537
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
2.10165
|
|
YRDC
|
yrdC N(6)-threonylcarbamoyltransferase domain containing
|
2.0657
|
|
RAI1
|
retinoic acid induced 1
|
2.06185
|
|
SRSF9
|
serine/arginine-rich splicing factor 9
|
2.03655
|
|
FKBP14
|
FK506 binding protein 14, 22 kDa
|
2.03
|
|
DCTPP1
|
dCTP pyrophosphatase 1
|
2.02325
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDC20
|
cell division cycle 20
|
-10.0
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-5.27115
|
|
GDF15
|
growth differentiation factor 15
|
-5.0
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-5.0
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-4.385
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.20315
|
|
GNAS
|
GNAS complex locus
|
-3.44168
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.43355
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.13205
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-3.07195
|
|
WDR7
|
WD repeat domain 7
|
-2.9855
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.96623
|
|
CAPN1
|
calpain 1, (mu/I) large subunit
|
-2.57975
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.44477
|
|
NDUFB4
|
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
|
-2.1991
|
|
GALP
|
galanin-like peptide
|
-2.08465
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.04553
|
|
AKAP8
|
A kinase (PRKA) anchor protein 8
|
-2.0013
|
