| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | n-(9h-fluoren-2-yl)-2,2,2-trifluoroacetamide 10.1 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
63 genes differentially expressed following the CRCGN011_HEPG2_24H:J20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KLHL9 | kelch-like family member 9 | 5.8366 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.21155 |
| AMDHD2 | amidohydrolase domain containing 2 | 5.0 |
| UBQLN2 | ubiquilin 2 | 4.88595 |
| NOTCH1 | notch 1 | 4.5951 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.55775 |
| PRKCH | protein kinase C, eta | 4.13867 |
| TLR4 | toll-like receptor 4 | 4.13695 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 4.11005 |
| PCDHB11 | protocadherin beta 11 | 3.80139 |
| IDE | insulin-degrading enzyme | 3.67835 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.47275 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 3.13995 |
| EPN2 | epsin 2 | 3.0592 |
| TBP | TATA box binding protein | 2.9097 |
| STK10 | serine/threonine kinase 10 | 2.83812 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.77962 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 2.65 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 2.5572 |
| SFTPB | surfactant protein B | 2.5154 |
| GATA2 | GATA binding protein 2 | 2.39442 |
| TOM1 | target of myb1 (chicken) | 2.3601 |
| COL11A1 | collagen, type XI, alpha 1 | 2.25995 |
| CYCS | cytochrome c, somatic | 2.184 |
| EVL | Enah/Vasp-like | 2.18105 |
| CCNF | cyclin F | 2.11567 |
| MEMO1 | mediator of cell motility 1 | 2.08555 |
| AFG3L2 | AFG3-like AAA ATPase 2 | 2.0682 |
| UGDH | UDP-glucose 6-dehydrogenase | 2.0553 |
| DMAC2L | distal membrane arm assembly component 2 like | 2.0061 |
| DOLK | dolichol kinase | 2.0047 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCDC86 | coiled-coil domain containing 86 | -5.5372 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -5.51115 |
| TSPAN4 | tetraspanin 4 | -5.12552 |
| LDHD | lactate dehydrogenase D | -5.048 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.80585 |
| GDF15 | growth differentiation factor 15 | -4.32165 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -4.1508 |
| MRPS2 | mitochondrial ribosomal protein S2 | -4.0708 |
| CHMP4B | charged multivesicular body protein 4B | -4.0637 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -3.94675 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.90695 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.7847 |
| GNAS | GNAS complex locus | -3.6825 |
| HMG20B | high mobility group 20B | -3.42203 |
| RPS5 | ribosomal protein S5 | -3.25625 |
| RGS2 | regulator of G-protein signaling 2 | -3.0935 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -2.98867 |
| P2RY10 | purinergic receptor P2Y, G-protein coupled, 10 | -2.422 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -2.40685 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.34298 |
| MMP3 | matrix metallopeptidase 3 | -2.28295 |
| DNAJA2 | DnaJ (Hsp40) homolog, subfamily A, member 2 | -2.27965 |
| PRAME | preferentially expressed antigen in melanoma | -2.27035 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -2.20455 |
| RIC8A | RIC8 guanine nucleotide exchange factor A | -2.17455 |
| GRN | granulin | -2.06138 |
| KRT24 | keratin 24, type I | -2.0577 |
| CCNB1 | cyclin B1 | -2.05105 |
| KIF21B | kinesin family member 21B | -2.0366 |
| ADRM1 | adhesion regulating molecule 1 | -2.00325 |
| MMP10 | matrix metallopeptidase 10 | -2.00245 |
| CCT2 | chaperonin containing TCP1, subunit 2 (beta) | -2.00207 |
