| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | n-(9h-fluoren-2-yl)-2,2,2-trifluoroacetamide 2.52 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
69 genes differentially expressed following the CRCGN011_HEPG2_24H:J22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BTK | Bruton agammaglobulinemia tyrosine kinase | 5.72465 |
| MYLK | myosin light chain kinase | 5.36155 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 5.35005 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.1619 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 5.04705 |
| PNKP | polynucleotide kinase 3'-phosphatase | 4.8372 |
| SQOR | sulfide quinone oxidoreductase | 4.8288 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.6856 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 4.64815 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 4.3601 |
| TLR4 | toll-like receptor 4 | 4.1658 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 4.12115 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.7022 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.0791 |
| CHN1 | chimerin 1 | 3.0248 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.93655 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.66427 |
| CALU | calumenin | 2.66094 |
| LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) | 2.54025 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.53083 |
| NFIL3 | nuclear factor, interleukin 3 regulated | 2.31525 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.31305 |
| MMD | monocyte to macrophage differentiation-associated | 2.23565 |
| SGSH | N-sulfoglucosamine sulfohydrolase | 2.2184 |
| POLR2K | polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa | 2.21285 |
| CD86 | CD86 molecule | 2.2042 |
| LPAR6 | lysophosphatidic acid receptor 6 | 2.14405 |
| SEC61G | Sec61 gamma subunit | 2.08645 |
| NID1 | nidogen 1 | 2.08083 |
| SCRN1 | secernin 1 | 2.0777 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | 2.05995 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 2.02435 |
| TPI1 | triosephosphate isomerase 1 | 2.0237 |
| FOXO3 | forkhead box O3 | 2.02154 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RGS2 | regulator of G-protein signaling 2 | -6.9555 |
| ENOPH1 | enolase-phosphatase 1 | -5.44415 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -5.32795 |
| CDC20 | cell division cycle 20 | -5.31545 |
| FASTKD5 | FAST kinase domains 5 | -5.30125 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -5.2716 |
| USP6NL | USP6 N-terminal like | -5.06135 |
| THAP11 | THAP domain containing 11 | -4.9341 |
| MAP7 | microtubule-associated protein 7 | -4.42323 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -4.3664 |
| CCNB2 | cyclin B2 | -3.9917 |
| GNAS | GNAS complex locus | -3.58194 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -3.54882 |
| CDC25B | cell division cycle 25B | -3.54835 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -3.443 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -3.28865 |
| TLCD3A | TLC domain containing 3A | -3.01085 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.9898 |
| PCNA | proliferating cell nuclear antigen | -2.9873 |
| HEATR1 | HEAT repeat containing 1 | -2.9841 |
| RBM34 | RNA binding motif protein 34 | -2.8946 |
| FAT1 | FAT atypical cadherin 1 | -2.5926 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -2.55638 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -2.51115 |
| ABHD17B | abhydrolase domain containing 17B | -2.42765 |
| RNF113A | ring finger protein 113A | -2.29185 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -2.26185 |
| TBCC | tubulin folding cofactor C | -2.1339 |
| KDM5D | lysine (K)-specific demethylase 5D | -2.1287 |
| SLC35F2 | solute carrier family 35, member F2 | -2.0828 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | -2.0636 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D | -2.05635 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -2.04765 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | -2.03605 |
| FERMT1 | fermitin family member 1 | -2.03575 |
