CRCGN011_HEPG2_24H:K03 Gene Set
Genes
57 genes differentially expressed following the CRCGN011_HEPG2_24H:K03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MYLK
|
myosin light chain kinase
|
10.0
|
|
NOTCH1
|
notch 1
|
5.3415
|
|
E2F2
|
E2F transcription factor 2
|
4.95985
|
|
NMU
|
neuromedin U
|
4.9401
|
|
UBQLN2
|
ubiquilin 2
|
4.93115
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.8662
|
|
CSK
|
c-src tyrosine kinase
|
4.66275
|
|
EPHA3
|
EPH receptor A3
|
4.56333
|
|
STIMATE
|
STIM activating enhancer
|
4.45385
|
|
MAP7
|
microtubule-associated protein 7
|
3.9046
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
3.54112
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.45545
|
|
TLR4
|
toll-like receptor 4
|
3.39095
|
|
PMM2
|
phosphomannomutase 2
|
3.0021
|
|
LCN2
|
lipocalin 2
|
2.85915
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.69825
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.40555
|
|
DPEP1
|
dipeptidase 1 (renal)
|
2.39
|
|
PIGB
|
phosphatidylinositol glycan anchor biosynthesis, class B
|
2.305
|
|
FRMD4B
|
FERM domain containing 4B
|
2.26595
|
|
FAT4
|
FAT atypical cadherin 4
|
2.18465
|
|
RNF167
|
ring finger protein 167
|
2.16545
|
|
FTO
|
fat mass and obesity associated
|
2.1644
|
|
KCTD5
|
potassium channel tetramerization domain containing 5
|
2.1588
|
|
ABCA2
|
ATP-binding cassette, sub-family A (ABC1), member 2
|
2.12762
|
|
PDZD8
|
PDZ domain containing 8
|
2.11865
|
|
SCGB1D2
|
secretoglobin, family 1D, member 2
|
2.1148
|
|
HAO2
|
hydroxyacid oxidase 2 (long chain)
|
2.08995
|
|
KLHL9
|
kelch-like family member 9
|
2.07053
|
|
BLNK
|
B-cell linker
|
2.02025
|
|
PTK2
|
protein tyrosine kinase 2
|
2.0181
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
VAT1
|
vesicle amine transport 1
|
-5.62065
|
|
TRIB3
|
tribbles pseudokinase 3
|
-5.17515
|
|
CD320
|
CD320 molecule
|
-4.69355
|
|
CCDC86
|
coiled-coil domain containing 86
|
-4.50385
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-4.4705
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.41375
|
|
GNAS
|
GNAS complex locus
|
-3.72791
|
|
CCNB2
|
cyclin B2
|
-3.4305
|
|
YME1L1
|
YME1-like 1 ATPase
|
-3.28513
|
|
SPAG4
|
sperm associated antigen 4
|
-3.05195
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.9747
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-2.80735
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
-2.79365
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.5708
|
|
RPS5
|
ribosomal protein S5
|
-2.48
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.3062
|
|
C5
|
complement component 5
|
-2.30265
|
|
TIMP4
|
TIMP metallopeptidase inhibitor 4
|
-2.2587
|
|
XPO7
|
exportin 7
|
-2.2317
|
|
DDB1
|
damage-specific DNA binding protein 1, 127kDa
|
-2.22485
|
|
CYP20A1
|
cytochrome P450, family 20, subfamily A, polypeptide 1
|
-2.1823
|
|
JAM2
|
junctional adhesion molecule 2
|
-2.14615
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.1108
|
|
RPLP1
|
ribosomal protein, large, P1
|
-2.05095
|
|
CNOT7
|
CCR4-NOT transcription complex, subunit 7
|
-2.04555
|
|
RPL39
|
ribosomal protein L39
|
-2.0123
|
