| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 3-(p-chlorophenyl)-1,1-di?methyl?urea 1.23 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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59 genes differentially expressed following the CRCGN011_HEPG2_24H:K06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.219 |
| LOC122526780 | uncharacterized LOC122526780 | 4.58075 |
| GSTZ1 | glutathione S-transferase zeta 1 | 4.01445 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.50102 |
| GPATCH8 | G patch domain containing 8 | 3.4301 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.13365 |
| NUP133 | nucleoporin 133kDa | 3.104 |
| VGLL4 | vestigial-like family member 4 | 3.08538 |
| MEST | mesoderm specific transcript | 3.008 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 2.94145 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.93657 |
| CHEK2 | checkpoint kinase 2 | 2.80958 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 2.66405 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.6511 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.6017 |
| FCHO1 | FCH domain only 1 | 2.58125 |
| RALGDS | ral guanine nucleotide dissociation stimulator | 2.52152 |
| COG2 | component of oligomeric golgi complex 2 | 2.4139 |
| RBM41 | RNA binding motif protein 41 | 2.40185 |
| CCNF | cyclin F | 2.35655 |
| CORO1A | coronin, actin binding protein, 1A | 2.34245 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.33337 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 2.3029 |
| CEP57 | centrosomal protein 57kDa | 2.28415 |
| CTSL | cathepsin L | 2.19635 |
| TBXT | T-box transcription factor T | 2.1709 |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 | 2.13495 |
| ZNF589 | zinc finger protein 589 | 2.10632 |
| VEZT | vezatin, adherens junctions transmembrane protein | 2.1001 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 2.02985 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 2.02535 |
| CDC45 | cell division cycle 45 | 2.02475 |
| TMEM51 | transmembrane protein 51 | 2.02375 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -8.0407 |
| ADI1 | acireductone dioxygenase 1 | -5.04345 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.94135 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.89775 |
| NGRN | neugrin, neurite outgrowth associated | -4.70045 |
| LDHD | lactate dehydrogenase D | -4.5564 |
| GTPBP8 | GTP-binding protein 8 (putative) | -4.5478 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -3.76385 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.5372 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.50975 |
| SCAND1 | SCAN domain containing 1 | -3.28295 |
| DCK | deoxycytidine kinase | -3.2684 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.09905 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -2.66505 |
| DECR1 | 2,4-dienoyl CoA reductase 1, mitochondrial | -2.61235 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.45723 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.39335 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.25796 |
| CGREF1 | cell growth regulator with EF-hand domain 1 | -2.21555 |
| PROS1 | protein S (alpha) | -2.1635 |
| PSMG1 | proteasome (prosome, macropain) assembly chaperone 1 | -2.13245 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 | -2.12332 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | -2.11825 |
| FAM168B | family with sequence similarity 168, member B | -2.10815 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -2.07095 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.00835 |
