CRCGN011_HEPG2_24H:K15 Gene Set
Genes
47 genes differentially expressed following the CRCGN011_HEPG2_24H:K15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CSK
|
c-src tyrosine kinase
|
6.82395
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
5.0467
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.8484
|
|
PLS1
|
plastin 1
|
4.79345
|
|
CGRRF1
|
cell growth regulator with ring finger domain 1
|
4.4539
|
|
RRAGA
|
Ras-related GTP binding A
|
3.6087
|
|
NMU
|
neuromedin U
|
3.56905
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
3.5605
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.50085
|
|
PFKL
|
phosphofructokinase, liver
|
3.22537
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.1692
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.97235
|
|
NUP133
|
nucleoporin 133kDa
|
2.86845
|
|
SCRN1
|
secernin 1
|
2.6496
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.6309
|
|
OXCT1
|
3-oxoacid CoA transferase 1
|
2.58005
|
|
EDEM1
|
ER degradation enhancer, mannosidase alpha-like 1
|
2.4096
|
|
GATD3
|
glutamine amidotransferase class 1 domain containing 3
|
2.2217
|
|
COL11A1
|
collagen, type XI, alpha 1
|
2.19395
|
|
GNB2
|
guanine nucleotide binding protein (G protein), beta polypeptide 2
|
2.18095
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
2.18065
|
|
LOC124907090
|
ankyrin repeat domain-containing protein SOWAHC-like
|
2.1636
|
|
RAB21
|
RAB21, member RAS oncogene family
|
2.1414
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-8.00485
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-5.3551
|
|
FASTKD5
|
FAST kinase domains 5
|
-5.3043
|
|
AKR7A2
|
aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
|
-5.182
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-5.1166
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-4.8375
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-4.761
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-4.1913
|
|
MAP7
|
microtubule-associated protein 7
|
-4.13432
|
|
RGS2
|
regulator of G-protein signaling 2
|
-3.40895
|
|
AKR7A3
|
aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
|
-3.2963
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.2704
|
|
AKAP8
|
A kinase (PRKA) anchor protein 8
|
-3.118
|
|
GNAS
|
GNAS complex locus
|
-3.08976
|
|
DCK
|
deoxycytidine kinase
|
-2.93485
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.7091
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
-2.57125
|
|
LRPAP1
|
low density lipoprotein receptor-related protein associated protein 1
|
-2.3021
|
|
ZNF586
|
zinc finger protein 586
|
-2.2731
|
|
RBM15B
|
RNA binding motif protein 15B
|
-2.1909
|
|
TOMM34
|
translocase of outer mitochondrial membrane 34
|
-2.12225
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
-2.0804
|
|
OTUD3
|
OTU deubiquitinase 3
|
-2.04
|
|
CD5L
|
CD5 molecule-like
|
-2.00995
|
