| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | isopropyl-n-(3-chloro?phenyl)carbamate 2.48 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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61 genes differentially expressed following the CRCGN011_HEPG2_24H:K17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPATCH8 | G patch domain containing 8 | 6.05177 |
| LCN2 | lipocalin 2 | 5.79825 |
| LAGE3 | L antigen family, member 3 | 5.54235 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 5.1463 |
| STAP2 | signal transducing adaptor family member 2 | 5.13805 |
| MYLK | myosin light chain kinase | 5.1285 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 5.01105 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.9768 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 4.08065 |
| MAP7 | microtubule-associated protein 7 | 3.59737 |
| TLR4 | toll-like receptor 4 | 3.5458 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 3.40975 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.3862 |
| ABHD6 | abhydrolase domain containing 6 | 2.9831 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.69027 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 2.55325 |
| TPD52L2 | tumor protein D52-like 2 | 2.5058 |
| SIRT3 | sirtuin 3 | 2.45355 |
| NOSIP | nitric oxide synthase interacting protein | 2.43905 |
| KLK11 | kallikrein-related peptidase 11 | 2.39225 |
| UBQLN2 | ubiquilin 2 | 2.38865 |
| GTF2H5 | general transcription factor IIH, polypeptide 5 | 2.36965 |
| MACROD1 | MACRO domain containing 1 | 2.36215 |
| EPS8L2 | EPS8-like 2 | 2.31195 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 | 2.3063 |
| MXRA7 | matrix-remodelling associated 7 | 2.29445 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | 2.29135 |
| TIPIN | TIMELESS interacting protein | 2.26 |
| S100A12 | S100 calcium binding protein A12 | 2.23085 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 | 2.1872 |
| CD151 | CD151 molecule (Raph blood group) | 2.16805 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.1492 |
| SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 | 2.13288 |
| TMEM80 | transmembrane protein 80 | 2.12912 |
| DERL2 | derlin 2 | 2.09265 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -5.33725 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -5.06905 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -5.0039 |
| LDHD | lactate dehydrogenase D | -4.53685 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -4.35065 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.28245 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.0844 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.9003 |
| EIF5 | eukaryotic translation initiation factor 5 | -3.74655 |
| GNAS | GNAS complex locus | -3.58259 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | -3.42835 |
| GDF15 | growth differentiation factor 15 | -3.40265 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -3.29365 |
| CDC25B | cell division cycle 25B | -2.6833 |
| HMG20B | high mobility group 20B | -2.6555 |
| PI4KA | phosphatidylinositol 4-kinase, catalytic, alpha | -2.514 |
| CCNB2 | cyclin B2 | -2.4814 |
| MVP | major vault protein | -2.46185 |
| TENT4A | terminal nucleotidyltransferase 4A | -2.27355 |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 | -2.2275 |
| STMN2 | stathmin 2 | -2.20852 |
| FAM13B | family with sequence similarity 13, member B | -2.19955 |
| GAP43 | growth associated protein 43 | -2.13635 |
| LGALS9C | lectin, galactoside-binding, soluble, 9C | -2.1141 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 | -2.09525 |
| HABP2 | hyaluronan binding protein 2 | -2.0038 |
