| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | p-chloroaniline 40.2 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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73 genes differentially expressed following the CRCGN011_HEPG2_24H:K19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYLK | myosin light chain kinase | 5.33725 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.24635 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 5.21775 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 5.1178 |
| LCN2 | lipocalin 2 | 5.0 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.95565 |
| DDIT4 | DNA-damage-inducible transcript 4 | 4.1822 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.04548 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 3.8431 |
| ABHD6 | abhydrolase domain containing 6 | 3.6473 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 3.2561 |
| TLR4 | toll-like receptor 4 | 3.228 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 3.1643 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 3.0728 |
| PRR15L | proline rich 15-like | 2.9939 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.9269 |
| GPATCH8 | G patch domain containing 8 | 2.92685 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.76525 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit | 2.64095 |
| CHN1 | chimerin 1 | 2.5617 |
| ABHD4 | abhydrolase domain containing 4 | 2.54535 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | 2.48215 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 2.4434 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.40542 |
| AARS1 | alanyl-tRNA synthetase 1 | 2.38515 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.2501 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 2.2158 |
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | 2.2087 |
| CD82 | CD82 molecule | 2.16235 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | 2.11435 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 2.1094 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 2.10122 |
| STXBP1 | syntaxin binding protein 1 | 2.095 |
| IRS2 | insulin receptor substrate 2 | 2.0637 |
| MECR | mitochondrial trans-2-enoyl-CoA reductase | 2.02745 |
| OTUD3 | OTU deubiquitinase 3 | 2.0139 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 2.00663 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VAT1 | vesicle amine transport 1 | -5.1891 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -5.15405 |
| GDF15 | growth differentiation factor 15 | -5.0 |
| LDHD | lactate dehydrogenase D | -4.85405 |
| MAP7 | microtubule-associated protein 7 | -4.8212 |
| DUSP6 | dual specificity phosphatase 6 | -4.70023 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.66145 |
| TRIB3 | tribbles pseudokinase 3 | -3.81925 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -3.30445 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.91203 |
| RAD51C | RAD51 paralog C | -2.8084 |
| SPAG4 | sperm associated antigen 4 | -2.7629 |
| DMAP1 | DNA methyltransferase 1 associated protein 1 | -2.70875 |
| SLC35F2 | solute carrier family 35, member F2 | -2.6596 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.64275 |
| TUBB6 | tubulin, beta 6 class V | -2.62045 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | -2.6058 |
| ZNF586 | zinc finger protein 586 | -2.53545 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.4103 |
| IMPACT | impact RWD domain protein | -2.34 |
| GATA6 | GATA binding protein 6 | -2.30045 |
| PRPF3 | pre-mRNA processing factor 3 | -2.2392 |
| ORC3 | origin recognition complex, subunit 3 | -2.23075 |
| HRAS | Harvey rat sarcoma viral oncogene homolog | -2.20095 |
| CBX2 | chromobox homolog 2 | -2.194 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | -2.18235 |
| E4F1 | E4F transcription factor 1 | -2.1513 |
| SNX11 | sorting nexin 11 | -2.13277 |
| CYP39A1 | cytochrome P450, family 39, subfamily A, polypeptide 1 | -2.1263 |
| CENPM | centromere protein M | -2.09555 |
| TM7SF3 | transmembrane 7 superfamily member 3 | -2.0907 |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 | -2.07255 |
| JPH3 | junctophilin 3 | -2.05365 |
| TDRD7 | tudor domain containing 7 | -2.0507 |
| PITX2 | paired-like homeodomain 2 | -2.03325 |
| FBXO7 | F-box protein 7 | -2.0035 |
