| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | p-chloroaniline 1.26 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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53 genes differentially expressed following the CRCGN011_HEPG2_24H:K24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 8.39205 |
| GSTZ1 | glutathione S-transferase zeta 1 | 8.2579 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.6039 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 5.20705 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.9252 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.75565 |
| MAMLD1 | mastermind-like domain containing 1 | 4.69105 |
| BZW2 | basic leucine zipper and W2 domains 2 | 4.5119 |
| NMU | neuromedin U | 4.1479 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.94653 |
| ALDOC | aldolase C, fructose-bisphosphate | 3.56795 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.3594 |
| ATP11B | ATPase, class VI, type 11B | 3.3425 |
| PIH1D1 | PIH1 domain containing 1 | 2.9604 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.75668 |
| COQ8A | coenzyme Q8A | 2.56905 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 2.55963 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 2.49007 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 2.26608 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 2.1708 |
| SHB | Src homology 2 domain containing adaptor protein B | 2.1658 |
| EPHA3 | EPH receptor A3 | 2.08498 |
| EMC8 | ER membrane protein complex subunit 8 | 2.0579 |
| AIFM1 | apoptosis-inducing factor, mitochondrion-associated, 1 | 2.0099 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -5.51115 |
| GDF15 | growth differentiation factor 15 | -5.0 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -5.0 |
| ZNF586 | zinc finger protein 586 | -4.87885 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.412 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.9402 |
| EIF5 | eukaryotic translation initiation factor 5 | -3.9282 |
| RGS2 | regulator of G-protein signaling 2 | -3.3433 |
| WASHC4 | WASH complex subunit 4 | -3.13325 |
| ZNF134 | zinc finger protein 134 | -2.95295 |
| YME1L1 | YME1-like 1 ATPase | -2.8932 |
| PCNA | proliferating cell nuclear antigen | -2.86075 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.49073 |
| IER3 | immediate early response 3 | -2.4062 |
| PSENEN | presenilin enhancer gamma secretase subunit | -2.3995 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.36385 |
| ZW10 | zw10 kinetochore protein | -2.3615 |
| TMEM176A | transmembrane protein 176A | -2.32445 |
| NFYB | nuclear transcription factor Y, beta | -2.28803 |
| TBCB | tubulin folding cofactor B | -2.24437 |
| PHF21A | PHD finger protein 21A | -2.2442 |
| SRSF9 | serine/arginine-rich splicing factor 9 | -2.21493 |
| ZNF329 | zinc finger protein 329 | -2.20615 |
| RNF167 | ring finger protein 167 | -2.1969 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -2.1639 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | -2.12967 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.12228 |
| NNMT | nicotinamide N-methyltransferase | -2.09518 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -2.05477 |
