CRCGN011_HEPG2_24H:L01 Gene Set
Genes
46 genes differentially expressed following the CRCGN011_HEPG2_24H:L01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
5.11715
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.92235
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
4.7652
|
|
MYLK
|
myosin light chain kinase
|
4.68305
|
|
STK10
|
serine/threonine kinase 10
|
4.2748
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.19895
|
|
TLR4
|
toll-like receptor 4
|
3.4485
|
|
SPTAN1
|
spectrin, alpha, non-erythrocytic 1
|
2.54885
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
2.53735
|
|
BAD
|
BCL2-associated agonist of cell death
|
2.35558
|
|
HMGA2
|
high mobility group AT-hook 2
|
2.32225
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
2.28185
|
|
PMM2
|
phosphomannomutase 2
|
2.25485
|
|
TBXA2R
|
thromboxane A2 receptor
|
2.24986
|
|
MAGEA6
|
melanoma antigen family A6
|
2.23405
|
|
DHX29
|
DEAH (Asp-Glu-Ala-His) box polypeptide 29
|
2.1747
|
|
RALB
|
v-ral simian leukemia viral oncogene homolog B
|
2.14048
|
|
RUFY1
|
RUN and FYVE domain containing 1
|
2.02975
|
|
OSBP
|
oxysterol binding protein
|
2.02015
|
|
ITGA6
|
integrin, alpha 6
|
2.00487
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-6.65555
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-5.7194
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-5.33725
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.917
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-4.8251
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-4.5677
|
|
MAP7
|
microtubule-associated protein 7
|
-4.51422
|
|
RPS5
|
ribosomal protein S5
|
-4.22855
|
|
COG2
|
component of oligomeric golgi complex 2
|
-4.16565
|
|
CD58
|
CD58 molecule
|
-3.35292
|
|
GNAS
|
GNAS complex locus
|
-3.22297
|
|
NR2F6
|
nuclear receptor subfamily 2, group F, member 6
|
-2.99165
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-2.9816
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
-2.7748
|
|
CIRBP
|
cold inducible RNA binding protein
|
-2.6581
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.5482
|
|
CA7
|
carbonic anhydrase VII
|
-2.4394
|
|
SNCA
|
synuclein, alpha (non A4 component of amyloid precursor)
|
-2.42956
|
|
TOPBP1
|
topoisomerase (DNA) II binding protein 1
|
-2.4027
|
|
FASTKD5
|
FAST kinase domains 5
|
-2.31825
|
|
TMBIM4
|
transmembrane BAX inhibitor motif containing 4
|
-2.24835
|
|
GDF15
|
growth differentiation factor 15
|
-2.1862
|
|
ATP8B1
|
ATPase, aminophospholipid transporter, class I, type 8B, member 1
|
-2.15935
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.12011
|
|
ZNF274
|
zinc finger protein 274
|
-2.0356
|
|
CST8
|
cystatin 8 (cystatin-related epididymal specific)
|
-2.02165
|
