| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | hc yellow 4 1.25 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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60 genes differentially expressed following the CRCGN011_HEPG2_24H:L06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 10.0 |
| FZD7 | frizzled class receptor 7 | 6.68455 |
| UBQLN2 | ubiquilin 2 | 5.776 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 5.6352 |
| PPARG | peroxisome proliferator-activated receptor gamma | 5.3183 |
| BIRC2 | baculoviral IAP repeat containing 2 | 4.9944 |
| ADRB2 | adrenoceptor beta 2, surface | 4.89485 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 4.63205 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.5819 |
| GSTZ1 | glutathione S-transferase zeta 1 | 4.3011 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 3.9826 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 3.8613 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.6014 |
| PFKL | phosphofructokinase, liver | 3.03487 |
| SOCS2 | suppressor of cytokine signaling 2 | 2.9862 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.91845 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.90307 |
| CCNF | cyclin F | 2.85042 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.70445 |
| PLSCR3 | phospholipid scramblase 3 | 2.67613 |
| TRIM13 | tripartite motif containing 13 | 2.6245 |
| ZNF589 | zinc finger protein 589 | 2.59112 |
| JADE2 | jade family PHD finger 2 | 2.50312 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | 2.3991 |
| ZNHIT6 | zinc finger, HIT-type containing 6 | 2.34825 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.21925 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 2.10385 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 2.06927 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | 2.06805 |
| BMS1 | BMS1 ribosome biogenesis factor | 2.06385 |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 | 2.00765 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -10.0 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -5.31608 |
| VAT1 | vesicle amine transport 1 | -5.25745 |
| PCNA | proliferating cell nuclear antigen | -5.04925 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | -4.5322 |
| DERA | deoxyribose-phosphate aldolase (putative) | -4.5152 |
| EIF5 | eukaryotic translation initiation factor 5 | -3.91671 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.7875 |
| HMG20B | high mobility group 20B | -3.67445 |
| GNAS | GNAS complex locus | -3.52914 |
| IFRD2 | interferon-related developmental regulator 2 | -3.23195 |
| TCTN1 | tectonic family member 1 | -3.15775 |
| PRPF4 | pre-mRNA processing factor 4 | -2.80268 |
| HEATR1 | HEAT repeat containing 1 | -2.70015 |
| GRN | granulin | -2.54315 |
| PROS1 | protein S (alpha) | -2.5001 |
| IPO13 | importin 13 | -2.4646 |
| RPP25 | ribonuclease P/MRP 25kDa subunit | -2.4498 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.39713 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.3798 |
| LOC124907782 | dual specificity protein phosphatase 22 | -2.26 |
| CP | ceruloplasmin (ferroxidase) | -2.2064 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | -2.19705 |
| HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 | -2.11695 |
| RSF1 | remodeling and spacing factor 1 | -2.10595 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | -2.09075 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 | -2.0488 |
| C4BPB | complement component 4 binding protein, beta | -2.04855 |
| CFI | complement factor I | -2.0348 |
