CRCGN011_HEPG2_24H:L09 Gene Set
Genes
43 genes differentially expressed following the CRCGN011_HEPG2_24H:L09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
10.0
|
|
MAMLD1
|
mastermind-like domain containing 1
|
5.12965
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.9567
|
|
MYLK
|
myosin light chain kinase
|
4.8987
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.7243
|
|
STK10
|
serine/threonine kinase 10
|
4.63532
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.6229
|
|
PRR15L
|
proline rich 15-like
|
2.95365
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.87225
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.61623
|
|
JADE2
|
jade family PHD finger 2
|
2.53758
|
|
GPATCH8
|
G patch domain containing 8
|
2.38708
|
|
MBOAT7
|
membrane bound O-acyltransferase domain containing 7
|
2.29118
|
|
TESK1
|
testis-specific kinase 1
|
2.2354
|
|
CD40
|
CD40 molecule, TNF receptor superfamily member 5
|
2.20041
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.1246
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.10437
|
|
CORO1A
|
coronin, actin binding protein, 1A
|
2.10095
|
|
ECD
|
ecdysoneless homolog (Drosophila)
|
2.05615
|
|
TSKU
|
tsukushi, small leucine rich proteoglycan
|
2.00505
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-5.19465
|
|
TRIB3
|
tribbles pseudokinase 3
|
-5.08165
|
|
ADI1
|
acireductone dioxygenase 1
|
-4.92835
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.90575
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.66275
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-4.11845
|
|
GNAS
|
GNAS complex locus
|
-3.62575
|
|
CASP3
|
caspase 3, apoptosis-related cysteine peptidase
|
-3.38065
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.33218
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.27075
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.2359
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.17105
|
|
ERC2
|
ELKS/RAB6-interacting/CAST family member 2
|
-2.94477
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.61648
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.50748
|
|
TTC33
|
tetratricopeptide repeat domain 33
|
-2.4943
|
|
SPAG4
|
sperm associated antigen 4
|
-2.4731
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.28215
|
|
SUGCT
|
succinyl-CoA:glutarate-CoA transferase
|
-2.1762
|
|
LZTFL1
|
leucine zipper transcription factor-like 1
|
-2.1537
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.1199
|
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8
|
-2.09905
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.0049
|
