| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 4,4'-thiodianiline 5.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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47 genes differentially expressed following the CRCGN011_HEPG2_24H:L10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 7.3489 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 5.1715 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.07545 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 4.70025 |
| MYLK | myosin light chain kinase | 4.6669 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.63935 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 4.47365 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.4691 |
| MSRA | methionine sulfoxide reductase A | 4.2155 |
| GSTZ1 | glutathione S-transferase zeta 1 | 4.13215 |
| CYCS | cytochrome c, somatic | 3.7616 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 3.23128 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 3.1035 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.8167 |
| CEP57 | centrosomal protein 57kDa | 2.81197 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.70305 |
| GPATCH8 | G patch domain containing 8 | 2.6829 |
| SLC38A6 | solute carrier family 38, member 6 | 2.39665 |
| MCM3 | minichromosome maintenance complex component 3 | 2.3626 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.35107 |
| MYOZ1 | myozenin 1 | 2.21595 |
| BMP4 | bone morphogenetic protein 4 | 2.1375 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.1174 |
| RBBP5 | retinoblastoma binding protein 5 | 2.09755 |
| VGLL4 | vestigial-like family member 4 | 2.05982 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -10.0 |
| CCNB2 | cyclin B2 | -7.4547 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -4.99715 |
| PCNA | proliferating cell nuclear antigen | -4.9283 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.8126 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.36085 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -4.17415 |
| HMG20B | high mobility group 20B | -3.91652 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.52675 |
| MTFR1 | mitochondrial fission regulator 1 | -3.48595 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -3.48378 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.45595 |
| GNAS | GNAS complex locus | -3.45119 |
| ACLY | ATP citrate lyase | -2.6311 |
| ADAR | adenosine deaminase, RNA-specific | -2.39245 |
| HAS2 | hyaluronan synthase 2 | -2.34995 |
| CAB39 | calcium binding protein 39 | -2.2169 |
| HPCAL1 | hippocalcin-like 1 | -2.20395 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -2.15375 |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | -2.03402 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV | -2.03055 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.01448 |
