| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 4,4'-thiodianiline 2.5 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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59 genes differentially expressed following the CRCGN011_HEPG2_24H:L11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NGRN | neugrin, neurite outgrowth associated | 5.2626 |
| NOTCH1 | notch 1 | 4.91165 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 4.53505 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.38265 |
| BIRC2 | baculoviral IAP repeat containing 2 | 4.3481 |
| CHN1 | chimerin 1 | 4.2265 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 4.0202 |
| TBPL1 | TBP-like 1 | 3.825 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 3.64173 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like | 3.63027 |
| SSBP2 | single-stranded DNA binding protein 2 | 3.49365 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 3.24217 |
| LCN2 | lipocalin 2 | 3.017 |
| RAI14 | retinoic acid induced 14 | 2.936 |
| KIF5C | kinesin family member 5C | 2.87113 |
| FZD7 | frizzled class receptor 7 | 2.84912 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.56565 |
| COL11A1 | collagen, type XI, alpha 1 | 2.55437 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.5334 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.3869 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 2.36285 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.30953 |
| MYG1 | MYG1 exonuclease | 2.20605 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 2.1688 |
| MAGEA6 | melanoma antigen family A6 | 2.1632 |
| CCP110 | centriolar coiled coil protein 110kDa | 2.11685 |
| BRINP1 | bone morphogenetic protein/retinoic acid inducible neural-specific 1 | 2.1081 |
| ZNF652 | zinc finger protein 652 | 2.07285 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.05705 |
| XPOT | exportin, tRNA | 2.0415 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -6.01315 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -5.46155 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -5.1787 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.06675 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -5.0264 |
| LDHD | lactate dehydrogenase D | -4.9799 |
| CD320 | CD320 molecule | -4.7915 |
| PCNA | proliferating cell nuclear antigen | -4.7455 |
| CHMP4B | charged multivesicular body protein 4B | -4.54747 |
| MAP7 | microtubule-associated protein 7 | -4.29357 |
| CCNB2 | cyclin B2 | -4.27175 |
| GNAS | GNAS complex locus | -3.55957 |
| NRIP1 | nuclear receptor interacting protein 1 | -3.3225 |
| ADI1 | acireductone dioxygenase 1 | -3.26485 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -3.21415 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -3.016 |
| DERA | deoxyribose-phosphate aldolase (putative) | -2.6937 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.5451 |
| S100G | S100 calcium binding protein G | -2.5 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.4883 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.3433 |
| UGT2A3 | UDP glucuronosyltransferase 2 family, polypeptide A3 | -2.29795 |
| SLC67A2 | solute carrier family 67 member 2 | -2.15633 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -2.1317 |
| IGSF1 | immunoglobulin superfamily, member 1 | -2.0488 |
| SLC19A3 | solute carrier family 19 (thiamine transporter), member 3 | -2.0349 |
| CBLIF | cobalamin binding intrinsic factor | -2.02505 |
| PCYOX1 | prenylcysteine oxidase 1 | -2.01385 |
| DRC11 | dynein regulatory complex subunit 11 | -2.0104 |
