| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 4-nitro-o-phenylenediamine 1.25 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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52 genes differentially expressed following the CRCGN011_HEPG2_24H:L18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL39L | ribosomal protein L39-like | 5.7409 |
| CSK | c-src tyrosine kinase | 5.35735 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 5.13815 |
| E2F2 | E2F transcription factor 2 | 4.6867 |
| UBQLN2 | ubiquilin 2 | 4.53535 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.41085 |
| ABHD6 | abhydrolase domain containing 6 | 4.17728 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 4.10255 |
| ABHD4 | abhydrolase domain containing 4 | 3.8192 |
| STIMATE | STIM activating enhancer | 3.74215 |
| TXNRD1 | thioredoxin reductase 1 | 3.1957 |
| TRIM16 | tripartite motif containing 16 | 3.14805 |
| JADE2 | jade family PHD finger 2 | 3.1283 |
| UGDH | UDP-glucose 6-dehydrogenase | 3.0403 |
| ATP11B | ATPase, class VI, type 11B | 3.03695 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.83808 |
| NTHL1 | nth endonuclease III-like 1 (E. coli) | 2.70805 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 2.64455 |
| LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 2.4086 |
| GPATCH8 | G patch domain containing 8 | 2.35448 |
| DIPK1A | divergent protein kinase domain 1A | 2.3449 |
| PAK1IP1 | PAK1 interacting protein 1 | 2.33325 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 2.2707 |
| CPAP | centrosome assembly and centriole elongation protein | 2.10045 |
| METRN | meteorin, glial cell differentiation regulator | 2.0934 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 2.0822 |
| ICAM3 | intercellular adhesion molecule 3 | 2.03005 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | 2.01115 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.98605 |
| LDHD | lactate dehydrogenase D | -4.9806 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -4.8888 |
| MAP7 | microtubule-associated protein 7 | -4.62378 |
| MRPS2 | mitochondrial ribosomal protein S2 | -4.3899 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.32355 |
| HMG20B | high mobility group 20B | -4.25378 |
| GNAS | GNAS complex locus | -3.29642 |
| WDR7 | WD repeat domain 7 | -3.07745 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -2.99437 |
| IPO13 | importin 13 | -2.8415 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.77622 |
| CTBP2 | C-terminal binding protein 2 | -2.72065 |
| ANAPC2 | anaphase promoting complex subunit 2 | -2.59895 |
| RAI14 | retinoic acid induced 14 | -2.46235 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.45988 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -2.35285 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | -2.30675 |
| GOLT1A | golgi transport 1A | -2.2928 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | -2.15885 |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase | -2.0936 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -2.08015 |
| COQ9 | coenzyme Q9 | -2.0669 |
| CCNH | cyclin H | -2.03855 |
