| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | retrorsine 1.21 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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78 genes differentially expressed following the CRCGN011_HEPG2_24H:L23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL39L | ribosomal protein L39-like | 5.3093 |
| CHMP6 | charged multivesicular body protein 6 | 5.18785 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | 4.9939 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.8155 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.8 |
| UBQLN2 | ubiquilin 2 | 4.6993 |
| AMDHD2 | amidohydrolase domain containing 2 | 4.1829 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 3.91905 |
| MAP7 | microtubule-associated protein 7 | 3.8282 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.6687 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.6547 |
| TESK1 | testis-specific kinase 1 | 3.47885 |
| GPATCH8 | G patch domain containing 8 | 3.19093 |
| LCN2 | lipocalin 2 | 3.15965 |
| CYB561 | cytochrome b561 | 3.15177 |
| PFKL | phosphofructokinase, liver | 3.088 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 | 2.7547 |
| COL11A1 | collagen, type XI, alpha 1 | 2.73158 |
| CHN1 | chimerin 1 | 2.69715 |
| CHEK2 | checkpoint kinase 2 | 2.53685 |
| BANF1 | barrier to autointegration factor 1 | 2.52415 |
| UQCRC1 | ubiquinol-cytochrome c reductase core protein I | 2.50725 |
| CH25H | cholesterol 25-hydroxylase | 2.4675 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.40692 |
| MCM3 | minichromosome maintenance complex component 3 | 2.3113 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 | 2.31075 |
| DIPK1A | divergent protein kinase domain 1A | 2.30988 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.3057 |
| PADI2 | peptidyl arginine deiminase, type II | 2.3028 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.26757 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.2638 |
| DGCR6L | DiGeorge syndrome critical region gene 6-like | 2.2094 |
| NPY | neuropeptide Y | 2.18315 |
| LDLRAP1 | low density lipoprotein receptor adaptor protein 1 | 2.18075 |
| FOXM1 | forkhead box M1 | 2.1587 |
| QPRT | quinolinate phosphoribosyltransferase | 2.1452 |
| RNF220 | ring finger protein 220 | 2.1217 |
| IFI6 | interferon, alpha-inducible protein 6 | 2.0697 |
| GPS1 | G protein pathway suppressor 1 | 2.0494 |
| MAPK6 | mitogen-activated protein kinase 6 | 2.0397 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 2.0397 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| SLC35F2 | solute carrier family 35, member F2 | -6.7846 |
| LAP3 | leucine aminopeptidase 3 | -5.9254 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.72925 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -4.63485 |
| GDF15 | growth differentiation factor 15 | -4.5051 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.1096 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -3.80635 |
| PCNA | proliferating cell nuclear antigen | -3.798 |
| KDM3A | lysine (K)-specific demethylase 3A | -3.39315 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -3.36155 |
| HEATR1 | HEAT repeat containing 1 | -3.27738 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -3.26113 |
| YME1L1 | YME1-like 1 ATPase | -2.88163 |
| PRPF4 | pre-mRNA processing factor 4 | -2.8358 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.67275 |
| RINT1 | RAD50 interactor 1 | -2.5123 |
| TOR4A | torsin family 4, member A | -2.4898 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -2.48342 |
| EPHA2 | EPH receptor A2 | -2.48225 |
| SNX11 | sorting nexin 11 | -2.44557 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 | -2.3962 |
| MAPRE1 | microtubule-associated protein, RP/EB family, member 1 | -2.35052 |
| ADGRA2 | adhesion G protein-coupled receptor A2 | -2.27635 |
| EXT1 | exostosin glycosyltransferase 1 | -2.25803 |
| POT1 | protection of telomeres 1 | -2.21267 |
| NPDC1 | neural proliferation, differentiation and control, 1 | -2.2126 |
| GATAD2A | GATA zinc finger domain containing 2A | -2.1921 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.17392 |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G | -2.15155 |
| AICDA | activation-induced cytidine deaminase | -2.15025 |
| CROT | carnitine O-octanoyltransferase | -2.11895 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | -2.06485 |
| ALAS2 | 5'-aminolevulinate synthase 2 | -2.0547 |
| CAV2 | caveolin 2 | -2.01178 |
| DSG2 | desmoglein 2 | -2.009 |
| ZNF185 | zinc finger protein 185 (LIM domain) | -2.0055 |
