CRCGN011_HEPG2_24H:M03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description resorcinol 9.75 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

61 genes differentially expressed following the CRCGN011_HEPG2_24H:M03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GPER1 G protein-coupled estrogen receptor 1 6.15882
RPP38 ribonuclease P/MRP 38kDa subunit 5.21625
LCN2 lipocalin 2 5.0
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.99045
CARMIL1 capping protein regulator and myosin 1 linker 1 4.7167
AMDHD2 amidohydrolase domain containing 2 4.6382
SQOR sulfide quinone oxidoreductase 4.5675
CIAO3 cytosolic iron-sulfur assembly component 3 4.40375
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.9524
SSBP2 single-stranded DNA binding protein 2 3.35267
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 3.3304
HPRT1 hypoxanthine phosphoribosyltransferase 1 3.0056
MEST mesoderm specific transcript 2.9392
WDTC1 WD and tetratricopeptide repeats 1 2.92935
STK10 serine/threonine kinase 10 2.78988
LOC122526780 uncharacterized LOC122526780 2.5269
GSTZ1 glutathione S-transferase zeta 1 2.40205
CYCS cytochrome c, somatic 2.39605
SMIM40 small integral membrane protein 40 2.28685
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.279
GARRE1 granule associated Rac and RHOG effector 1 2.2773
BAD BCL2-associated agonist of cell death 2.27172
UBA2 ubiquitin-like modifier activating enzyme 2 2.25135
DOCK2 dedicator of cytokinesis 2 2.23865
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific 2.2262
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 2.16875
CORT cortistatin 2.15715
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.10788
UGP2 UDP-glucose pyrophosphorylase 2 2.0879
PARP2 poly (ADP-ribose) polymerase 2 2.0774
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 2.07445
DOK5 docking protein 5 2.0486
ADGRA3 adhesion G protein-coupled receptor A3 2.0433
CASP10 caspase 10, apoptosis-related cysteine peptidase 2.02826
DEPTOR DEP domain containing MTOR-interacting protein 2.00375

decreased expression

Symbol Name Standardized Value
TUBB6 tubulin, beta 6 class V -5.46165
TM9SF3 transmembrane 9 superfamily member 3 -5.3459
CDC20 cell division cycle 20 -5.0
FBXL12 F-box and leucine-rich repeat protein 12 -4.86285
ZMIZ1 zinc finger, MIZ-type containing 1 -4.5834
FABP5 fatty acid binding protein 5 (psoriasis-associated) -3.7279
GRWD1 glutamate-rich WD repeat containing 1 -3.6206
GDF15 growth differentiation factor 15 -3.2057
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -2.9973
SLC35F2 solute carrier family 35, member F2 -2.97805
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -2.9207
TOMM34 translocase of outer mitochondrial membrane 34 -2.5897
TMSB4X thymosin beta 4, X-linked -2.45185
C5 complement component 5 -2.44035
BPHL biphenyl hydrolase-like (serine hydrolase) -2.34585
WASHC4 WASH complex subunit 4 -2.28758
SPAG4 sperm associated antigen 4 -2.2679
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa -2.2366
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 -2.18325
NMT1 N-myristoyltransferase 1 -2.17292
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -2.1624
CDC42SE1 CDC42 small effector 1 -2.1293
ESRP2 epithelial splicing regulatory protein 2 -2.1195
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 -2.0716
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae) -2.0596
TCFL5 transcription factor-like 5 (basic helix-loop-helix) -2.04115