CRCGN011_HEPG2_24H:M06 Gene Set
Genes
36 genes differentially expressed following the CRCGN011_HEPG2_24H:M06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
E2F2
|
E2F transcription factor 2
|
4.92
|
|
TLR4
|
toll-like receptor 4
|
4.78415
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.49045
|
|
STK10
|
serine/threonine kinase 10
|
4.47568
|
|
ABHD4
|
abhydrolase domain containing 4
|
4.0092
|
|
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1
|
3.868
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.56525
|
|
MMP2
|
matrix metallopeptidase 2
|
3.3412
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.8335
|
|
PMM2
|
phosphomannomutase 2
|
2.34435
|
|
TPD52L2
|
tumor protein D52-like 2
|
2.28105
|
|
RALGDS
|
ral guanine nucleotide dissociation stimulator
|
2.2294
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
2.21345
|
|
TRAM2
|
translocation associated membrane protein 2
|
2.10252
|
|
PIGB
|
phosphatidylinositol glycan anchor biosynthesis, class B
|
2.10135
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.09075
|
|
CLEC2D
|
C-type lectin domain family 2, member D
|
2.08895
|
|
GPATCH8
|
G patch domain containing 8
|
2.05485
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
2.0546
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-8.28825
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-7.9872
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.56735
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-3.60855
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.52115
|
|
GNAS
|
GNAS complex locus
|
-3.443
|
|
CHIC2
|
cysteine-rich hydrophobic domain 2
|
-2.93895
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.77295
|
|
LGMN
|
legumain
|
-2.66455
|
|
SNX11
|
sorting nexin 11
|
-2.6445
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
-2.39615
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.3744
|
|
BIK
|
BCL2-interacting killer (apoptosis-inducing)
|
-2.3067
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.18685
|
|
RNF167
|
ring finger protein 167
|
-2.1575
|
|
WASHC4
|
WASH complex subunit 4
|
-2.05458
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.05155
|
