CRCGN011_HEPG2_24H:M07 Gene Set
Genes
55 genes differentially expressed following the CRCGN011_HEPG2_24H:M07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
6.9528
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
6.08915
|
|
KLHL9
|
kelch-like family member 9
|
5.3683
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
4.95405
|
|
NOTCH1
|
notch 1
|
4.892
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.889
|
|
TLR4
|
toll-like receptor 4
|
4.69015
|
|
EPHB2
|
EPH receptor B2
|
4.57827
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
3.9719
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.702
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
3.55255
|
|
SATB1
|
SATB homeobox 1
|
3.52205
|
|
WDTC1
|
WD and tetratricopeptide repeats 1
|
3.18147
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.13243
|
|
GATA3
|
GATA binding protein 3
|
2.9513
|
|
CHN1
|
chimerin 1
|
2.5883
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.48472
|
|
CD101
|
CD101 molecule
|
2.391
|
|
LPAR6
|
lysophosphatidic acid receptor 6
|
2.22265
|
|
CASP10
|
caspase 10, apoptosis-related cysteine peptidase
|
2.20906
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.18103
|
|
DPYD
|
dihydropyrimidine dehydrogenase
|
2.1556
|
|
LTA4H
|
leukotriene A4 hydrolase
|
2.1483
|
|
ANP32B
|
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
|
2.12935
|
|
DPEP1
|
dipeptidase 1 (renal)
|
2.0892
|
|
FANCF
|
Fanconi anemia, complementation group F
|
2.08195
|
|
CACNA2D2
|
calcium channel, voltage-dependent, alpha 2/delta subunit 2
|
2.0788
|
|
HMG20A
|
high mobility group 20A
|
2.0329
|
|
PTGER2
|
prostaglandin E receptor 2 (subtype EP2), 53kDa
|
2.0183
|
|
CSF3R
|
colony stimulating factor 3 receptor (granulocyte)
|
2.0097
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-5.485
|
|
AARS1
|
alanyl-tRNA synthetase 1
|
-5.0347
|
|
COG2
|
component of oligomeric golgi complex 2
|
-4.88455
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-4.1505
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.95225
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.78157
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-3.58795
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.43485
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-3.32175
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.06473
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.73332
|
|
RASIP1
|
Ras interacting protein 1
|
-2.5282
|
|
TFF2
|
trefoil factor 2
|
-2.5018
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.40985
|
|
CLTB
|
clathrin, light chain B
|
-2.26517
|
|
TRAPPC2L
|
trafficking protein particle complex 2-like
|
-2.2375
|
|
DUSP5
|
dual specificity phosphatase 5
|
-2.21605
|
|
NPTXR
|
neuronal pentraxin receptor
|
-2.1677
|
|
ARAP2
|
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
|
-2.15455
|
|
GSDME
|
gasdermin E
|
-2.1186
|
|
SREK1IP1
|
SREK1-interacting protein 1
|
-2.0992
|
|
TSPYL2
|
TSPY-like 2
|
-2.07665
|
|
SQSTM1
|
sequestosome 1
|
-2.02952
|
|
DAG1
|
dystroglycan 1 (dystrophin-associated glycoprotein 1)
|
-2.0151
|
|
OSBPL3
|
oxysterol binding protein-like 3
|
-2.00975
|
