CRCGN011_HEPG2_24H:M08 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description carbon-tetrachloride 19.7 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

47 genes differentially expressed following the CRCGN011_HEPG2_24H:M08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PEX11A peroxisomal biogenesis factor 11 alpha 5.5442
RPP38 ribonuclease P/MRP 38kDa subunit 5.44055
PPARG peroxisome proliferator-activated receptor gamma 5.1188
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 4.86762
MNAT1 MNAT CDK-activating kinase assembly factor 1 4.84705
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 4.81295
MEST mesoderm specific transcript 4.80385
DYNLT3 dynein, light chain, Tctex-type 3 4.25555
SLC38A6 solute carrier family 38, member 6 3.3639
HEBP1 heme binding protein 1 3.2486
TLR4 toll-like receptor 4 3.1556
GPATCH8 G patch domain containing 8 3.14925
RXYLT1 ribitol xylosyltransferase 1 3.089
SSBP2 single-stranded DNA binding protein 2 3.00742
CCNF cyclin F 2.71565
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.63703
GIN1 gypsy retrotransposon integrase 1 2.6237
ADAT1 adenosine deaminase, tRNA-specific 1 2.6052
BLM Bloom syndrome, RecQ helicase-like 2.5684
GSTZ1 glutathione S-transferase zeta 1 2.39335
GFOD1 glucose-fructose oxidoreductase domain containing 1 2.38275
SCARA3 scavenger receptor class A, member 3 2.24805
CRELD2 cysteine-rich with EGF-like domains 2 2.1462
COQ4 coenzyme Q4 2.14275
BAMBI BMP and activin membrane-bound inhibitor 2.0554
CEP57 centrosomal protein 57kDa 2.05132
EGLN3 egl-9 family hypoxia-inducible factor 3 2.0257
NHEJ1 nonhomologous end-joining factor 1 2.0245
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 2.00095

decreased expression

Symbol Name Standardized Value
ADI1 acireductone dioxygenase 1 -9.18405
GNAS GNAS complex locus -7.10046
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -5.11995
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -4.87395
GDF15 growth differentiation factor 15 -4.7398
LDHD lactate dehydrogenase D -4.64705
TCFL5 transcription factor-like 5 (basic helix-loop-helix) -4.1031
YME1L1 YME1-like 1 ATPase -3.2067
AZGP1 alpha-2-glycoprotein 1, zinc-binding -2.66852
GAMT guanidinoacetate N-methyltransferase -2.61745
MARCO macrophage receptor with collagenous structure -2.48185
CNPY3-GNMT CNPY3-GNMT readthrough -2.262
PLA2G1B phospholipase A2, group IB (pancreas) -2.17305
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.15205
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa -2.0983
IL13RA2 interleukin 13 receptor, alpha 2 -2.06875
RFC2 replication factor C (activator 1) 2, 40kDa -2.0669
IFI6 interferon, alpha-inducible protein 6 -2.0215