CRCGN011_HEPG2_24H:M09 Gene Set
Genes
36 genes differentially expressed following the CRCGN011_HEPG2_24H:M09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
5.99585
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
5.08715
|
|
LCN2
|
lipocalin 2
|
5.0
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.9768
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.85415
|
|
CCNF
|
cyclin F
|
4.57855
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
4.178
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
4.06095
|
|
PRR15L
|
proline rich 15-like
|
3.9512
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.13305
|
|
NMU
|
neuromedin U
|
2.91665
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.86715
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.85037
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.73472
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
2.64887
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.63578
|
|
FKBP14
|
FK506 binding protein 14, 22 kDa
|
2.5804
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.40387
|
|
GPATCH8
|
G patch domain containing 8
|
2.35737
|
|
RRAGA
|
Ras-related GTP binding A
|
2.07895
|
|
CXCL3
|
chemokine (C-X-C motif) ligand 3
|
2.00355
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-5.00555
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.886
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.443
|
|
CCNB2
|
cyclin B2
|
-4.27085
|
|
MTFR1
|
mitochondrial fission regulator 1
|
-4.11735
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-4.00315
|
|
GNAS
|
GNAS complex locus
|
-3.5109
|
|
CPNE3
|
copine III
|
-2.94193
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.7686
|
|
CDC25B
|
cell division cycle 25B
|
-2.75515
|
|
IPO13
|
importin 13
|
-2.46985
|
|
PHKB
|
phosphorylase kinase, beta
|
-2.21525
|
|
CAPN10
|
calpain 10
|
-2.1674
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.16297
|
|
CHIC2
|
cysteine-rich hydrophobic domain 2
|
-2.0265
|
