CRCGN011_HEPG2_24H:M11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description carbon-tetrachloride 2.46 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

35 genes differentially expressed following the CRCGN011_HEPG2_24H:M11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 9.75165
LCN2 lipocalin 2 5.34535
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 5.04455
MAMLD1 mastermind-like domain containing 1 4.96125
PRR15L proline rich 15-like 4.92205
STIMATE STIM activating enhancer 4.6614
UBQLN2 ubiquilin 2 4.28115
PPP1R13B protein phosphatase 1, regulatory subunit 13B 3.8965
RNF167 ring finger protein 167 3.4213
LYN LYN proto-oncogene, Src family tyrosine kinase 3.26513
SSBP2 single-stranded DNA binding protein 2 3.20988
ATP11B ATPase, class VI, type 11B 3.0536
HOOK2 hook microtubule-tethering protein 2 2.94157
PLSCR3 phospholipid scramblase 3 2.64438
GPATCH8 G patch domain containing 8 2.54133
TPD52L2 tumor protein D52-like 2 2.46925
CCNF cyclin F 2.41585
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.3533
JADE2 jade family PHD finger 2 2.30568
MAGEA6 melanoma antigen family A6 2.292
BZW2 basic leucine zipper and W2 domains 2 2.24675
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 2.17513
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 2.0841

decreased expression

Symbol Name Standardized Value
NT5DC2 5'-nucleotidase domain containing 2 -5.2621
TSEN2 TSEN2 tRNA splicing endonuclease subunit -4.8174
CHMP4B charged multivesicular body protein 4B -4.11287
TARBP1 TAR (HIV-1) RNA binding protein 1 -4.09935
CDC25B cell division cycle 25B -2.76955
OXA1L oxidase (cytochrome c) assembly 1-like -2.73305
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.53102
IRX4 iroquois homeobox 4 -2.26985
GDF15 growth differentiation factor 15 -2.22635
RAP1GAP RAP1 GTPase activating protein -2.17645
TAOK3 TAO kinase 3 -2.0385
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -2.0121